The Registry of Toxic Effects of Chemical Substances

Phosphoric acid, bis (2 - ethylhexyl) ester

RTECS #: TB7875000

CAS #: 298-07-7

UPDATE: October 1997 MW: 322.48 MF: C16H35O4P


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. SKIN AND EYE IRRITATION DATA:
  3. ACUTE TOXICITY DATA:
  4. STATUS IN FEDERAL AGENCIES:
  5. REFERENCES:

SYNONYMS:

  1. Dehpa extractant
  2. Di (2 - ethylhexyl) orthophosphoric acid
  3. Di (2 - ethylhexyl) phosphate
  4. Di - 2 (ethylhexyl) phosphoric acid
  5. 2 - Ethyl - 1 - hexanol hydrogen phosphate
  6. Bis (2 - ethylhexyl) hydrogen phosphate
  1. Bis (2 - ethylhexyl) orthophosphoric acid
  2. Bis (2 - ethylhexyl) phosphate
  3. Bis (2 - ethylhexyl) phosphoric acid
  4. Hdehp
  5. Kyselina di - (2 - ethylhexyl) fosforecna (Czech)


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
eye
rabbit 		5 mg moderate UCDS** 5/18/1972
eye
rabbit 		250 µg/24 hour severe 85JCAE -,1130,1986
skin
rabbit 		500 mg open irritation test moderate UCDS** 5/18/1972
skin
rabbit 		5 mg/24 hour severe 85JCAE -,1130,1986


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
intraperitoneal
mouse 		lowest published lethal dose: 62,500 µg/kg N/R CBCCT* 9,132,1957
intraperitoneal
rat 		lethal dose (50 percent kill): 50 mg/kg Liver: Other changes HYDRDA 3,201,1978
oral
rat 		lethal dose (50 percent kill): 4,940 µL/kg N/R UCDS** 5/18/1972
skin
rabbit 		lethal dose (50 percent kill): 1,250 µL/kg N/R UCDS** 5/18/1972


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
N/R N/R N/R


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used in liquid-liquid extraction of heavy metals
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986
CBCCT* "Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. (National Academy of Science Library, 2101 Constitution Ave., NW, Washington, DC 20418)
HYDRDA Hydrometallurgy. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1975-
UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817)

Used in liquid-liquid extraction of heavy metals

RTECS Compound Description:
   Primary Irritant

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