The Registry of Toxic Effects of Chemical Substances

Phosphoric acid, aluminum salt (1:1)

RTECS #: TB6450000

CAS #: 7784-30-7


UPDATE: May 2004 MW: 121.95 MF: O4P•Al


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. ACUTE TOXICITY DATA:
  3. OTHER MULTIPLE DOSE DATA:
  4. REVIEWS:
  5. STANDARDS AND REGULATIONS:
  6. NIOSH DOCUMENTATION AND SURVEILLANCE:
  7. STATUS IN FEDERAL AGENCIES:
  8. REFERENCES:

SYNONYMS:

  1. Aluphos
  2. Aluminiumphosphat (German)
  3. Aluminophosphoric acid
  4. Aluminum acid phosphate
  5. Aluminum monophosphate
  1. Aluminum phosphate
  2. Aluminum phosphate (1:1)
  3. FFB 32
  4. Monoaluminum phosphate
  5. Phosphalugel


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE
DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
oral
mouse
lethal dose (50 percent kill): >5 gm/kg N/R EPXXDW #0006458
oral
rat
lowest published lethal dose: 4,640 mg/kg Behavioral: Somnolence (general depressed activity)

Gastrointestinal: Other changes
NTIS** OTS0571153
skin
rabbit
lethal dose (50 percent kill): >4,640 mg/kg Skin: After systemic exposure: Dermatitis, irritative

Skin: After systemic exposure: Dermatitis, other
NTIS** OTS0571153


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
oral
rat
lowest published toxic dose: 8.75 mL/kg/7 day- intermittent Gastrointestinal: Alteration in gastric secretion EKFAE9 62,37,1999


REVIEWS:

ORGANIZATION STANDARD
REFERENCE

American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 2 mg(Al)/m3 DTLVS* TLV/BEI,1999


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE

Occupational Exposure Limit - AUSTRALIA time-weighted average 2 mg(Al)/m3, JAN1993
Occupational Exposure Limit - BELGIUM time-weighted average 2 mg(Al)/m3, JAN1993
Occupational Exposure Limit - DENMARK time-weighted average 2 mg(Al)/m3, JAN1999
Occupational Exposure Limit - FRANCE VME 2 mg(Al)/m3, JAN1999
Occupational Exposure Limit - RUSSIA time-weighted average 2 mg(Al)/m3, JAN1993
Occupational Exposure Limit - SWEDEN NGV 2 mg(Al)/m3, JAN1999
Occupational Exposure Limit - SWITZERLAND MAK- week 2 mg(Al)/m3, JAN1999
Occupational Exposure Limit - UNITED KINGDOM time-weighted average 2 mg/m3, SEP2000
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN, KOREA American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

time-weighted average 2 mg(Al)/m3
Occupational Exposure Limit IN NEW ZEALAND, SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
time-weighted average 2 mg(Al)/m3


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE

National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 81696;
Number of Industries 22;
Total Number of Facilities 609;
Number of Occupations 26;
Total Number of Employees Exposed 5,948
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: X9205;
Number of Industries 1;
Total Number of Facilities 31;
Number of Occupations 2;
Total Number of Employees Exposed 4,228;
Total Number of Female Employees Exposed 4,088
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 81696;
Number of Industries 24;
Total Number of Facilities 1,302;
Number of Occupations 28;
Total Number of Employees Exposed 19,522;
Total Number of Female Employees Exposed 6,122


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE

EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used as an antacid and as a cement component, flux for ceramics, dental cements, glass, gels
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE

DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
EKFAE9 Eksperimental'naya i Klinicheskaya Farmakologiya. Experimental and Clinical Pharmacology. (Mezhdunarodnaya Kniga, ul. B. Yakimanka, 39, 117049 Moscow, Russia) V.55- 1992-
EPXXDW European Patent Application. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231)
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.

Used as an antacid and as a cement component, flux for ceramics, dental cements, glass, gels

NIOSH PROFILE (ALUMINUM and ITS COMPOUNDS), SRC, 1/81

FDA-over the counter drug

RTECS Compound Description:
   Drug

ALT CAS #: 13765-93-0
ALT CAS #: 51668-55-4
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