The Registry of Toxic Effects of Chemical Substances

Peroxide, bis (alpha,alpha - dimethylbenzyl)

RTECS #: SD8150000

CAS #: 80-43-3

UPDATE: February 2004 MW: 270.40 MF: C18H22O2


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. ACUTE TOXICITY DATA:
  3. NIOSH DOCUMENTATION AND SURVEILLANCE:
  4. STATUS IN FEDERAL AGENCIES:
  5. REFERENCES:

SYNONYMS:

  1. Active dicumyl peroxide
  2. Cumene peroxide
  3. Cumyl peroxide
  4. Dicumyl peroxide
  5. Di - alpha - cumyl peroxide
  6. Di - Cup
  7. Di - Cup 40 KE
  8. Di - cupr
  1. Diisopropylbenzene peroxide
  2. Bis (alpha,alpha - dimethylbenzyl) peroxide
  3. Isopropylbenzene peroxide
  4. Luperox 500R
  5. Luperox 500T
  6. Peroxide, bis (1 - methyl - 1 - phenylethyl)
  7. Varox dcp - R
  8. Varox dcp - T


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
intraperitoneal
mouse 		lethal dose (50 percent kill): 5,000 mg/kg N/R VCVGK* -,536,1994
oral
mouse 		lethal dose (50 percent kill): 5,000 mg/kg N/R VCVGK* -,536,1994
oral
rat 		lethal dose (50 percent kill): 4,100 mg/kg N/R BSPII* 1/75-19B
oral
rat 		lethal dose (50 percent kill): 6,000 mg/kg Behavioral: Somnolence (general depressed activity)

Behavioral: Food intake (animal)

Gastrointestinal: Hypermotility, diarrhea 		VCVGK* -,536,1994
subcutaneous
cat 		lowest published toxic dose: 1,000 mg/kg Blood: Methemoglobinemia- Carboxhemoglobinemia VCVGK* -,536,1994
subcutaneous
rat 		lowest published toxic dose: 1,000 mg/kg Blood: Methemoglobinemia- Carboxhemoglobinemia VCVGK* -,536,1994
unreported route
rat 		lethal dose (50 percent kill): 3,500 mg/kg N/R 34ZIAG -,655,1969


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 80273;
Number of Industries 7;
Total Number of Facilities 256;
Number of Occupations 25;
Total Number of Employees Exposed 5,641
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 80273;
Number of Industries 11;
Total Number of Facilities 606;
Number of Occupations 26;
Total Number of Employees Exposed 17,958;
Total Number of Female Employees Exposed 8,122


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used in electrical applications and as crosslinker for rubber
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE
34ZIAG "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969
BSPII* SPI Bulletin. (Soc. of the Plastics Industry, 250 Park Ave., New York, NY 10017)
VCVGK* "Vrednie chemichescie veshestva, galogen I kislorod sodergashie organicheskie soedinenia". (Hazardous substances. Galogen and oxygen containing substances), Bandman A.L. et al., Chimia, 1994.

Used in electrical applications and as crosslinker for rubber

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