The Registry of Toxic Effects of Chemical Substances

Perchloric acid, potassium salt (1:1)

RTECS #: SC9700000

CAS #: 7778-74-7

UPDATE: February 2003 MW: 138.55 MF: ClO4•K


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. REPRODUCTIVE EFFECTS DATA:
  3. OTHER MULTIPLE DOSE DATA:
  4. NIOSH DOCUMENTATION AND SURVEILLANCE:
  5. STATUS IN FEDERAL AGENCIES:
  6. REFERENCES:

SYNONYMS:

  1. Astrumal
  2. Potassium hyperchloride
  1. Potassium perchlorate
  2. Periodin


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
oral
guinea pig 		lowest published toxic dose: 35,700 mg/kg (48-68 day pregnant) Reproductive: Specific developmental abnormalities: Endocrine system ENDOAO 60,53,1957
oral
rat 		lowest published toxic dose: 27,675 mg/kg (1-9 day pregnant) Reproductive: Specific developmental abnormalities: Endocrine system JRPFA4 27,265,1971
oral
rabbit 		lowest published toxic dose: 2,100 mg/kg (1-21 day pregnant) Reproductive: Specific developmental abnormalities: Endocrine system AMASA4 23,223,1967


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
oral
rat 		lowest published toxic dose: 7,980 mg/kg/19 week- continuous Endocrine: Other changes

Endocrine: Changes in thymus weight 		JJCREP 78,1335,1987


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 80603;
Number of Industries 2;
Total Number of Facilities 142;
Number of Occupations 4;
Total Number of Employees Exposed 332
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 80603;
Number of Industries 5;
Total Number of Facilities 286;
Number of Occupations 8;
Total Number of Employees Exposed 2,640;
Total Number of Female Employees Exposed 1,948


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY


REFERENCES:

CODEN
REFERENCE
AMASA4 Acta Medica Academiae Scientiarum Hungaricae. (Budapest, Hungary) V.1-39, 1950-82.
ENDOAO Endocrinology (Baltimore). (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21203) V.1- 1917-
JJCREP Japanese Journal of Cancer Research. (Elsevier Science Pub. BV, POB 211, 1000 AE Amsterdam, Netherlands) V.76- 1985-
JRPFA4 Journal of Reproduction and Fertility. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1960-

Used as oxidizer in analysis, pyrotechnics

FDA-proprietary drug

RTECS Compound Description:
   Reproductive Effector

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