RTECS:RS2100000 The Registry of Toxic Effects of Chemical Substances | CDC/NIOSH

The Registry of Toxic Effects of Chemical Substances

Oxygen difluoride

RTECS #: RS2100000

CAS #: 7783-41-7

UPDATE: November 2004 MW: 54.00 MF: F₂O

NOTE:

TOXICITY DATA HAVE NOT BEEN EVALUATED. OMISSION OF A SUBSTANCE OR NOTATION DOES NOT IMPLY ANY RELIEF FROM REGULATORY RESPONSIBILITY.

TABLE OF CONTENTS:

SYNONYMS:

REPRODUCTIVE EFFECTS DATA:

ACUTE TOXICITY DATA:

REVIEWS:

STANDARDS AND REGULATIONS:

NIOSH DOCUMENTATION AND SURVEILLANCE:

REFERENCES:

SYNONYMS:

Fluorine monoxide

Fluorine oxide

Oxygen difluoride (ACGIH:OSHA)

Oxygen fluoride

SKIN AND EYE IRRITATION DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

MUTATION DATA AND REFERENCES:
SYSTEM TEST ROUTE/
ORGANISM/
TISSUE DOSE REFERENCE
N/R N/R N/R N/R

REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
inhalation
rat lowest published toxic concentration: 5 mg/m³ (multigenerations) Reproductive: Specific developmental abnormalities: Blood and lymphatic systems (including spleen and marrow) VCVN5* -,359,1989

TUMORIGENIC DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
inhalation
cat lowest published lethal concentration: 71 mg/m³/2 hour Peripheral Nerve and Sensation: Spastic paralysis with/without sensory change

Lung, Thorax, or Respiration: Fibrosis, focal (pneumoconiosis)

Lung, Thorax, or Respiration: Acute pulmonary edema STGNBT -,232,1999
inhalation
dog lethal concentration (50 percent kill): 26 ppm/1 hour Lung, Thorax, or Respiration: Acute pulmonary edema

Lung, Thorax, or Respiration: Other changes AMRL** TR-70-77,1970
inhalation
human lowest published toxic concentration: 500 ppb Lung, Thorax, or Respiration: Chronic pulmonary edema or congestion 34ZIAG -,444,1969
inhalation
mammal (species unspecified) lethal concentration (50 percent kill): 480 mg/m³/5 minute N/R VCVN5* -,359,1989
inhalation
monkey lethal concentration (50 percent kill): 26 ppm/1 hour Behavioral: Muscle weakness

Lung, Thorax, or Respiration: Chronic pulmonary edema or congestion

Gastrointestinal: Nausea or vomiting AMRL TR-70-77,1970
inhalation
mouse lethal concentration (50 percent kill): 1,500 ppb/1 hour Lung, Thorax, or Respiration: Acute pulmonary edema

Lung, Thorax, or Respiration: Other changes AMRL TR-70-77,1970
inhalation
rat lethal concentration (50 percent kill): 2,600 ppb/1 hour Lung, Thorax, or Respiration: Acute pulmonary edema

Lung, Thorax, or Respiration: Other changes AMRL TR-70-77,1970

OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

REVIEWS:
ORGANIZATION STANDARD
REFERENCE**

American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value ceiling concentration 0.05 ppm DTLVS* TLV/BEI,2003

STANDARDS AND REGULATIONS:
ORGANIZATION STANDARD
REFERENCE

Mine Safety and Health Administration (MSHA) STANDARD - air time-weighted average 0.05 ppm (0.1 mg/m³) DTLVS* 3,193,1971
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) 8 hour time-weighted average 0.05 ppm (0.1 mg/m³) CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) 8 hour time-weighted average 0.05 ppm (0.1 mg/m³) CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) 8 hour time-weighted average 0.05 ppm (0.1 mg/m³) CFRGBR 29,1915.1000,1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors) 8 hour time-weighted average 0.05 ppm (0.1 mg/m³) CFRGBR 41,50-204.50,1994
Occupational Exposure Limit - ARAB Republic of Egypt time-weighted average 0.05 ppm (0.1 mg/m³), JAN1993
Occupational Exposure Limit - AUSTRIA MAK 2.5 mg(F)/m³, JAN1999
Occupational Exposure Limit - DENMARK time-weighted average 0.05 ppm (0.1 mg/m³), JAN1999
Occupational Exposure Limit - FINLAND short term exposure limit 0.05 ppm (0.1 mg/m³), JAN1999
Occupational Exposure Limit - NORWAY time-weighted average 0.05 ppm (0.1 mg/m³), JAN1999
Occupational Exposure Limit - THE PHILIPPINES time-weighted average 0.05 ppm (0.1 mg/m³), JAN1993
Occupational Exposure Limit - POLAND MAC(time-weighted average) 1 mg(HF)/m³, MAC(short term exposure limit) 3 mg(HF)/m³, JAN1999
Occupational Exposure Limit - THE NETHERLANDS MAC- continuous 0.1 mg/m³, 2003
Occupational Exposure Limit - UNITED KINGDOM time-weighted average 2.5 mg(F)/m³, SEP2000
Occupational Exposure Limit IN NEW ZEALAND, SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
ceiling concentration 0.05 ppm

NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION STANDARD or SURVEY
REFERENCE

National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO OXYGEN DIFLUORIDE-air ceiling concentration 0.05 ppm NIOSH* DHHS #92-100,1992

STATUS IN FEDERAL AGENCIES:
ORGANIZATION
REFERENCE

N/R

REFERENCES:
CODEN
REFERENCE

34ZIAG "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969
AMRL** Aerospace Medical Research Laboratory Report. (Aerospace Technical Div., Air Force Systems Command, Wright-Patterson Air Force Base, OH 45433)
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402)
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
NIOSH* National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda.
STGNBT "Spravochnik po Toksikologii i Gigienicheskim Normativam (PDK) Potentsial'no Opasnykh Khimicheskikh Veshchestv" Kushneva, V.S., and R.B. Gorshkova, eds. 46, Zhivopisnaya St., 123182, Moscow, Russia, IzdAT 1999
VCVN5* "Vrednie chemichescie veshestva. Neorganicheskie soedinenia elementov V-VII groopp" (Hazardous substances. Inornanic substances containing V-VII group elements), Bandman A.L. et al., Chimia, 1989.

Used as an oxidizer for rocker propellants

RTECS Compound Description:
Reproductive Effector
Human Data

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