The Registry of Toxic Effects of Chemical Substances
2 - Octanol |
UPDATE: February 2003 | MW: 130.26 | MF: C8H18O |
SYNONYMS:
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SKIN AND EYE IRRITATION DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
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N/R |
N/R
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N/R
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N/R
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MUTATION DATA AND REFERENCES:
SYSTEM TEST
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ROUTE/ | ORGANISM/ TISSUE
DOSE
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REFERENCE
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N/R
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N/R
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N/R
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N/R
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REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
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N/R |
N/R
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N/R
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N/R
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TUMORIGENIC DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
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N/R |
N/R
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N/R
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N/R
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ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
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oral | guinea pig
lethal dose (50 percent kill): 9,300 mg/kg
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Brain and Coverings: Other degenerative changes | Liver: Other changes Kidney, Ureter, and Bladder: Other changes
VCVGK* -,115,1984
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oral | human
lowest published lethal dose: 428.6 mg/kg
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N/R
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VCVGK* -,116,1984
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oral | mouse
lethal dose (50 percent kill): 300 mg/kg
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Brain and Coverings: Other degenerative changes | Liver: Other changes Kidney, Ureter, and Bladder: Other changes
VCVGK* -,115,1984
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oral | rat
lethal dose (50 percent kill): 200 mg/kg
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Brain and Coverings: Other degenerative changes | Liver: Other changes Kidney, Ureter, and Bladder: Other changes
VCVGK* -,115,1984
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oral | rabbit
lethal dose (50 percent kill): 9,300 mg/kg
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Brain and Coverings: Other degenerative changes | Liver: Other changes Kidney, Ureter, and Bladder: Other changes
VCVGK* -,115,1984
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unreported route | mammal (species unspecified)
lethal dose (50 percent kill): 6,934 mg/kg
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N/R
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GISAAA 51(5),61,1986
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OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
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inhalation | rat
lowest published toxic concentration: 180 mg/m3/2 hour/137 day- intermittent
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Brain and Coverings: Other degenerative changes | Liver: Other changes Kidney, Ureter, and Bladder: Other changes
VCVGK* -,116,1994
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REVIEWS:
ORGANIZATION
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STANDARD
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REFERENCE
N/R
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N/R
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N/R
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STANDARDS AND REGULATIONS:
ORGANIZATION
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STANDARD
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REFERENCE
N/R
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N/R
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N/R
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NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION
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STANDARD or SURVEY
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REFERENCE
National Occupational Hazard Survey 1974
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National Occupational Hazard Survey 1974: Hazard Code: 82155; | Number of Industries 5; Total Number of Facilities 158; Number of Occupations 6; Total Number of Employees Exposed 1,265
National Occupational Exposure Survey 1983
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National Occupational Exposure Survey 1983: Hazard Code: 82155; |
Number of Industries 3; Total Number of Facilities 132; Number of Occupations 4; Total Number of Employees Exposed 3,640; Total Number of Female Employees Exposed 1,361 |
STATUS IN FEDERAL AGENCIES:
ORGANIZATION
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REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
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EPA TSCA Section 8(d) unpublished health/safety studies
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EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
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REFERENCES:
CODEN
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REFERENCE
GISAAA
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Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga,
113095 Moscow, USSR) V.1- 1936-
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VCVGK*
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"Vrednie chemichescie veshestva, galogen I kislorod sodergashie organicheskie soedinenia".
(Hazardous substances. Galogen and oxygen containing substances), Bandman A.L. et al., Chimia,
1994.
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