The Registry of Toxic Effects of Chemical Substances

Octadecylamine

RTECS #: RG4150000

CAS #: 124-30-1

UPDATE: May 2003 MW: 269.58 MF: C18H39N


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. SKIN AND EYE IRRITATION DATA:
  3. ACUTE TOXICITY DATA:
  4. OTHER MULTIPLE DOSE DATA:
  5. NIOSH DOCUMENTATION AND SURVEILLANCE:
  6. STATUS IN FEDERAL AGENCIES:
  7. REFERENCES:

SYNONYMS:

  1. Adogenen 142
  2. Alamine 7
  3. Alamine 7D
  4. Amine AB
  5. 1 - Aminooctadecane
  6. Armeen 18
  7. Armeen 18D
  8. Armofilm
  9. Crodamine 1.18D
  10. Farmin 80
  1. Kemamine P990
  2. Monooctadecylamine
  3. Nissan amine AB
  4. Stearamine
  5. Stearylamine
  6. n - Stearylamine
  7. n - Octadecylamine
  8. 1 - Octadecylamine
  9. Oktadecylamin (Czech)


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
skin
rabbit 		20 mg/24 hour moderate 85JCAE -,439,1986


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
intraperitoneal
mouse 		lethal dose (50 percent kill): 250 mg/kg N/R NTIS** AD691-490
oral
mouse 		lethal dose (50 percent kill): 3 gm/kg Behavioral: Somnolence (general depressed activity) GISAAA 38(11),31,1973
oral
rat 		lethal dose (50 percent kill): 2,395 mg/kg Behavioral: Somnolence (general depressed activity) GISAAA 38(11),31,1973


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
intramuscular
dog 		lowest published toxic dose: 5,475 mg/kg/1 year- continuous Gastrointestinal: Gastritis

Gastrointestinal: Other changes 		EPASR* #40-8484004,2000
intramuscular
rat 		lowest published toxic dose: 31,350 mg/kg/209 day- continuous Gastrointestinal: Gastritis

Gastrointestinal: Other changes 		EPASR* #40-8484004,2000
oral
rat 		lowest published toxic dose: 313 gm/kg/30 week- continuous Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field JACTDZ 14,196,1995


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 83376;
Number of Industries 9;
Total Number of Facilities 166;
Number of Occupations 9;
Total Number of Employees Exposed 1,676
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 83376;
Number of Industries 13;
Total Number of Facilities 634;
Number of Occupations 11;
Total Number of Employees Exposed 4,674;
Total Number of Female Employees Exposed 363


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986
EPASR* United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW, Washington, DC 20460) History unknown.
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued.
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.

NIOSH PROFILE (AMINES, PRIMARY ALIPHATIC), SRI, 2/77

RTECS Compound Description:
   Primary Irritant

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