The Registry of Toxic Effects of Chemical Substances

Naphthalene, 1,2,3,4 - tetrahydro -

RTECS #: QK3850000

CAS #: 119-64-2

UPDATE: February 2004 MW: 132.22 MF: C10H12


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. SKIN AND EYE IRRITATION DATA:
  3. ACUTE TOXICITY DATA:
  4. STANDARDS AND REGULATIONS:
  5. NIOSH DOCUMENTATION AND SURVEILLANCE:
  6. STATUS IN FEDERAL AGENCIES:
  7. REFERENCES:

SYNONYMS:

  1. Naphthalene 1,2,3,4 - tetrahydride
  2. Delta (sup 5,7,9) - naphthantriene
  3. Tetrahydronaphthalene
  4. 1,2,3,4 - Tetrahydronaphthalene
  1. Tetralin
  2. Tetralina (Polish)
  3. Tetraline
  4. Tetranap


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
skin
human 		2.5%/24 hour JIDEAE 24,303,1991
skin
rabbit 		500 mg open irritation test severe UCDS** 1/12/1972


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
inhalation
guinea pig 		lethal concentration (50 percent kill): 275 ppm N/R 85JCAE -,47,1986
inhalation
human 		lowest published toxic concentration: 1 gm/m3/1 minute Lung, Thorax, or Respiration: Cough VCVGH* -,229,1990
oral
rat 		lethal dose (50 percent kill): 1,620 µL/kg N/R UCDS** 1/12/1972
skin
rabbit 		lethal dose (50 percent kill): 17,300 µL/kg N/R UCDS** 1/12/1972


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
Occupational Exposure Limit - POLAND MAC(time-weighted average) 100 mg/m3, MAC(short term exposure limit) 300 mg/m3, JAN1999


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 84671;
Number of Industries 11;
Total Number of Facilities 622;
Number of Occupations 13;
Total Number of Employees Exposed 2,237
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 84671;
Number of Industries 2;
Total Number of Facilities 117;
Number of Occupations 3;
Total Number of Employees Exposed 504;
Total Number of Female Employees Exposed 146


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used as solvent for oils, resins, waxes, rubber, and asphalt, rubber chemical intermediate
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NTP Carcinogenesis studies; test completed (peer review), October 2000


REFERENCES:

CODEN
REFERENCE
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986
JIDEAE Journal of Investigative Dermatology. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1938-
UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817)
VCVGH* "Vrednie chemichescie veshestva, galogenproisvodnie uglevodorodov". (Hazardous substances: Galogenated hydrocarbons) Bandman A.L. et al., Chimia, 1990.

Used as solvent for oils, resins, waxes, rubber, and asphalt, rubber chemical intermediate

RTECS Compound Description:
   Tumorigen
   Human Data
   Primary Irritant

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