The Registry of Toxic Effects of Chemical Substances

4,7 - Methanoindan, 1,2,4,5,6,7,8,8 - octachloro - 3a,4,7,7a - tetrahydro -

RTECS #: PB9800000

CAS #: 57-74-9

UPDATE: May 2005 MW: 409.76 MF: C10H6Cl8


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. MUTATION DATA:
  3. REPRODUCTIVE EFFECTS DATA:
  4. TUMORIGENIC DATA:
  5. ACUTE TOXICITY DATA:
  6. OTHER MULTIPLE DOSE DATA:
  7. REVIEWS:
  8. STANDARDS AND REGULATIONS:
  9. NIOSH DOCUMENTATION AND SURVEILLANCE:
  10. STATUS IN FEDERAL AGENCIES:
  11. REFERENCES:

SYNONYMS:

  1. 1,2,4,5,6,7,10,10 - Octachloro - 4,7,8,9 - tetrahydro - 4,7 - methyleneindane
  2. 1,2,4,5,6,7,8,8 - Octachloor - 3a,4,7,7a - tetrahydro - 4,7 - endo - methano - indaan (Dutch)
  3. 1,2,4,5,6,7,8,8 - Octachlor - 2,3,3a,4,7,7a - hexahydro - 4,7 - methanoindane
  4. 1,2,4,5,6,7,8,8 - Octachlor - 3a,4,7,7a - tetrahydro - 4,7 - endo - methano - indan (German)
  5. 1,2,4,5,6,7,8,8 - Octachloro - 2,3,3a,4,7,7a - hexahydro - 4,7 - methano - 1H - indene
  6. 1,2,4,5,6,7,8,8 - Octachloro - 2,3,3a,4,7,7a - hexahydro - 4,7 - methanoindene
  7. 1,2,4,5,6,7,8,8 - Octachloro - 3a,4,7,7a - hexahydro - 4,7 - methylene indane
  8. 1,2,4,5,6,7,8,8 - Octachloro - 3a,4,7,7a - tetrahydro - 4,7 - methanoindane
  9. 1,2,4,5,6,7,8,8 - Octachloro - 4,7 - methano - 3a,4,7,7a - tetrahydroindane
  10. 1,2,4,5,6,7,8,8 - Octahydro - 2,3,3a,4,7,7a - hexahydro - 4,7 - methanoindan
  11. 1,2,4,5,6,7,8,8 - Ottochloro - 3a,4,7,7a - tetraidro - 4,7 - endo - metano - indano (Italian)
  12. 4,7 - Methano - 1H - indene, 1,2,4,5,6,7,8,8 - octachloro - 2,3,3a,4,7,7a - hexahydro -
  13. Aspon - chlordane
  14. BELT
  15. CD 68
  16. Chloordaan (Dutch)
  17. Chlor KIL
  18. Chlordan
  19. Chlordane
  20. Chlordane (ACGIH:OSHA)
  21. Chlorindan
  22. Chlorodane
  23. Chlortox
  24. Clordan (Italian)
  25. Clordano
  26. Cortilan - neu
  27. Dichlorochlordene
  28. Dowchlor
  29. ENT 25,552 - X
  1. ENT 9,932
  2. HCS 3260
  3. Kilex lindane
  4. Kypchlor
  5. Latka 1068 (Czech)
  6. M 140
  7. NCI - C00099
  8. OMS 1437
  9. Octa - klor
  10. Octachlor
  11. Octachloro - 4,7 - methanohydroindane
  12. Octachloro - 4,7 - methanotetrahydroindane
  13. Octachlorodihydrodicyclopentadiene
  14. Oktaterr
  15. Ortho - klor
  16. RCRA waste number U036
  17. SD 5532
  18. Shell SD - 5532
  19. Starchlor
  20. Synklor
  21. TAT chlor 4
  22. Termi - ded
  23. Topichlor 20
  24. Topiclor
  25. Topiclor 20
  26. Toxichlor
  27. Unexan - koeder
  28. Velsicol 1068


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
cytogenetic analysis oral
mouse 		10 mg/kg MUREAV 301,33,1993
unscheduled DNA synthesis human fibroblast 1 µmol/L MUREAV 42,161,1977
mutation in mammalian somatic cells hamster lung 10 µmol/L CBINA8 19,369,1977
morphological transform oral
rat 		1,260 mg/kg/6 week CRNGDP 9,387,1988
other mutation test systems oral
mouse 		35 mg/kg MUREAV 343,157,1995
phage inhibition capacity Escherichia coli 3,050 µmol/L MUREAV 182,193,1987
sister chromatid exchange human lymphocyte 10 µmol/L ARTODN 52,221,1983
sister chromatid exchange multiple
other fish 		54 pmol/L MUREAV 118,61,1983


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
oral
mouse 		lowest published toxic dose: 3,360 µg/kg (1-21 day pregnant) Reproductive: Specific developmental abnormalities: Endocrine system

Reproductive: Effects on newborn: Biochemical and metabolic 		JEPTDQ 2(2),357,1978
oral
mouse 		lowest published toxic dose: 152 mg/kg (1-19 day pregnant) Reproductive: Specific developmental abnormalities: Immune and reticuloendothelial system TXAPA9 62,402,1982
oral
mouse 		lowest published toxic dose: 7 mg/kg (15-21 day pregnant) Reproductive: Effects on newborn: Behavioral BJPCBM 49,311,1973
oral
mouse 		lowest published toxic dose: 3,040 µg/kg (1-19 day pregnant) Reproductive: Effects on newborn: Biochemical and metabolic ENVRAL 35,204,1984
oral
mouse 		lowest published toxic dose: 2,625 mg/kg (5 week male) Reproductive: Paternal effects: Spermatogenesis (including genetic material, sperm morphology, motility, and count)

Reproductive: Paternal effects: Testes, epididymis, sperm duct 		TOLED5 115,1,2000
unreported route
mouse 		lowest published toxic dose: 168 mg/kg (1-21 day pregnant) Reproductive: Effects on newborn: Delayed effects APTOD9 19,A18,1980
unreported route
mouse 		lowest published toxic dose: 168 mg/kg (1-21 day pregnant) Reproductive: Specific developmental abnormalities: Immune and reticuloendothelial system TJADAB 19,23A,1979


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
oral
mouse 		lowest published toxic dose: 2,020 mg/kg/80 week- continuous Tumorigenic: Carcinogenic by RTECS criteria

Liver: Tumors 		NCITR* NCI-TR-8,1977
oral
mouse 		toxic dose : 3,780 mg/kg/80 week- continuous Tumorigenic: Carcinogenic by RTECS criteria

Liver: Tumors 		NCITR* NCI-TR-8,1977


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
inhalation
cat 		lethal concentration (50 percent kill): 100 mg/m3/4 hour Behavioral: Somnolence (general depressed activity)

Behavioral: Convulsions or effect on seizure threshold

Behavioral: Excitement 		GTPZAB 8(4),30,1964
inhalation
mammal (species unspecified) 		lethal concentration (50 percent kill): >20 gm/m3/4 hour N/R PEMNDP 9,139,1991
intraperitoneal
mouse 		lowest published lethal dose: 240 mg/kg N/R TXAPA9 23,288,1972
intraperitoneal
rat 		lethal dose (50 percent kill): 343 mg/kg N/R TXAPA9 32,443,1975
intraperitoneal
rat 		lowest published toxic dose: 25 mg/kg Biochemical: Metabolism (intermediary): Other ENDOAO 82,406,1968
intravenous
mouse 		lethal dose (50 percent kill): 100 mg/kg N/R CSLNX* NX#04876
intravenous
rabbit 		lowest published lethal dose: 10 mg/kg N/R AIHOAX 1,13,1950
oral
cat 		lethal dose (50 percent kill): 100 mg/kg N/R VCVGH* -,565,1990
oral
chicken 		lethal dose (50 percent kill): 220 mg/kg N/R PCOC** -,226,1966
oral
duck 		lethal dose (50 percent kill): 1,200 mg/kg N/R DOEAAH 35,25,1979
oral
domestic animal 		lethal dose (50 percent kill): 50 mg/kg N/R YKYUA6 32,471,1981
oral
hamster 		lethal dose (50 percent kill): 1,720 mg/kg N/R EJTXAZ 7,159,1974
oral
human 		lowest published lethal dose: 29 mg/kg Liver: Fatty liver degeneration CMEP** -,1,1956
oral
mammal (species unspecified) 		lethal dose (50 percent kill): 180 mg/kg N/R PCOC** -,226,1966
oral
man 		lowest published toxic dose: 3,071 µg/kg Behavioral: Coma

Lung, Thorax, or Respiration: Dyspnea

Gastrointestinal: Nausea or vomiting 		JTCTDW 20,291,1983
oral
mouse 		lethal dose (50 percent kill): 145 mg/kg N/R ARSIM* 20,19,1966
oral
rat 		lethal dose (50 percent kill): 200 mg/kg N/R ARZNAD 17,614,1967
oral
rat 		lethal dose (50 percent kill): 200 mg/kg/24 hour Behavioral: Convulsions or effect on seizure threshold

Lung, Thorax, or Respiration: Respiratory depression

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.) 		TAEHC* VI:34 ,1,1984
oral
rabbit 		lethal dose (50 percent kill): 100 mg/kg N/R PCOC** -,226,1966
oral
woman 		lowest published lethal dose: 120 µg/kg Behavioral: Convulsions or effect on seizure threshold

Behavioral: Excitement

Gastrointestinal: Gastritis 		CMEP** -,1,1956
skin
human 		lowest published lethal dose: 428 mg/kg Behavioral: Tremor

Behavioral: Convulsions or effect on seizure threshold

Behavioral: Ataxia 		34ZIAG -,648,1969
skin
rat 		lethal dose (50 percent kill): 690 mg/kg N/R JAVMA4 157,1835,1970
skin
rabbit 		lethal dose (50 percent kill): 780 mg/kg N/R 85DPAN -,-,1971/1976
unreported route
human 		lowest published lethal dose: 25 mg/kg/24 hour N/R TAEHC* VI:34 ,1,1984
unreported route
man 		lowest published lethal dose: 118 mg/kg N/R 85DCAI 2,73,1970


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
inhalation
rat 		lowest published toxic concentration: 28,200 µg/m3/8 hour/28 day- intermittent Liver: Changes in liver weight

Kidney, Ureter, and Bladder: Changes in bladder weight

Blood: Changes in serum composition (e.g. TP, bilirubin, cholesterol) 		JTEHD6 28,327,1989
inhalation
rat 		lowest published toxic concentration: 10 mg/m3/8 hour/90 day- intermittent Liver: Changes in liver weight

Kidney, Ureter, and Bladder: Changes in bladder weight

Nutritional and Gross Metabolic: Changes in: Ca 		JTEHD6 28,327,1989
intraperitoneal
rat 		lowest published toxic dose: 125 mg/kg/5 day- intermittent Liver: Changes in liver weight

Biochemical: Metabolism (intermediary): Other 		ENDOAO 82,406,1968
intraperitoneal
rat 		lowest published toxic dose: 500 mg/kg/10 day- intermittent Endocrine: Androgenic

Endocrine: Estrogenic

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.) 		CLPTAT 14,727,1976
oral
rat 		lowest published toxic dose: 410 mg/kg/39 week- continuous Liver: Other changes AMPLAO 64,614,1957
oral
rat 		lowest published toxic dose: 660 mg/kg/15 day- intermittent Behavioral: Convulsions or effect on seizure threshold

Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field 		AMIHBC 7,197,1953
oral
rat 		lowest published toxic dose: 6,512 mg/kg/58 week- intermittent Liver: Changes in liver weight

Nutritional and Gross Metabolic: Weight loss or decreased weight gain 		AMIHBC 7,197,1953
oral
rat 		lowest published toxic dose: 5,475 mg/kg/2 year- continuous Liver: Hepatitis (hepatocellular necrosis), zonal

Liver: Changes in liver weight

Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field 		AMIHBC 6,357,1952
oral
rat 		lowest published toxic dose: 504 mg/kg/12 week- continuous Blood: Changes in serum composition (e.g. TP, bilirubin, cholesterol)

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: True cholinesterase 		APTOD9 19,A99,1980


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 0.5 mg/m3 (skin) DTLVS* TLV/BEI,2003
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value Confirmed Animal Carcinogen with Unknown DTLVS* TLV/BEI,2003
International Agency for Research on Cancer (IARC) Cancer Review Animal Sufficient Evidence IMEMDT 20,45,1979
International Agency for Research on Cancer (IARC) Cancer Review Animal Limited Evidence IMSUDL 7,146,1987
International Agency for Research on Cancer (IARC) Cancer Review Animal Sufficient Evidence IMEMDT 53,115,1991
International Agency for Research on Cancer (IARC) Cancer Review Human Inadequate Evidence IMEMDT 20,45,1979
International Agency for Research on Cancer (IARC) Cancer Review Human Inadequate Evidence IMEMDT 53,115,1991
International Agency for Research on Cancer (IARC) Cancer Review Group 2B IMEMDT 53,115,1991
TOXICOLOGY REVIEW
CNDQA8 10(3),43,1975
TOXICOLOGY REVIEW
RREVAH 56,107,1975
TOXICOLOGY REVIEW
BNYMAM 54,413,1978
TOXICOLOGY REVIEW
CTOXAO 13,231,1978
TOXICOLOGY REVIEW
MUREAV 567,109,2004


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC 54,7740,1989
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF PESTICIDES: Cancelled RBREV* -,96,1998
Mine Safety and Health Administration (MSHA) STANDARD - air time-weighted average 0.5 mg/m3 (skin) DTLVS* 3,44,1971
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) 8 hour time-weighted average 0.5 mg/m3 (skin) CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) 8 hour time-weighted average 0.5 mg/m3 (skin) CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) 8 hour time-weighted average 0.5 mg/m3 (skin) CFRGBR 29,1915.1000,1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors) 8 hour time-weighted average 0.5 mg/m3 (skin) CFRGBR 41,50-204.50,1994
Occupational Exposure Limit - ARAB Republic of Egypt time-weighted average 0.5 mg/m3, Skin, JAN1993
Occupational Exposure Limit - AUSTRALIA time-weighted average 0.5 mg/m3, short term exposure limit 2 mg/m3, Skin, Carcinogen JAN1993
Occupational Exposure Limit - AUSTRIA MAK 0.5 mg/m3, Skin, Suspected Carcinogen, JAN1999
Occupational Exposure Limit - BELGIUM time-weighted average 0.5 mg/m3, short term exposure limit 2 mg/m3, Skin, JAN1993
Occupational Exposure Limit - DENMARK time-weighted average 0.5 mg/m3, Skin, JAN1999
Occupational Exposure Limit - FINLAND Carcinogen, JAN1999
Occupational Exposure Limit - FRANCE VME 0.5 mg/m3, Skin, continuous3 Carcinogen, JAN1999
Occupational Exposure Limit - GERMANY MAK 0.5 mg/m3, Skin, Carcinogen, JAN1999
Occupational Exposure Limit - THE NETHERLANDS MAC-TGG 0.5 mg/m3, Skin, 2003
Occupational Exposure Limit - NORWAY time-weighted average 0.5 mg/m3, JAN1999
Occupational Exposure Limit - THE PHILIPPINES time-weighted average 0.5 mg/m3, Skin, JAN1993
Occupational Exposure Limit - RUSSIA short term exposure limit 0.01 mg/m3, Skin, JAN1993
Occupational Exposure Limit - SWITZERLAND MAK- week 0.5 mg/m3, Skin, JAN1999
Occupational Exposure Limit - THAILAND time-weighted average 0.5 mg/m3, JAN1993
Occupational Exposure Limit - TURKEY time-weighted average 0.5 mg/m3, Skin, JAN1993
Occupational Exposure Limit - UNITED KINGDOM LTEL 0.5 mg/m3, short term exposure limit 2 mg/m3, Skin, JAN1993
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN, KOREA American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

Confirmed Animal Carcinogen with Unknown
Occupational Exposure Limit IN NEW ZEALAND, SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
Confirmed Animal Carcinogen with Unknown


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO CHLORDANE-air Carcinogen;
10 hour time-weighted average 0.5 mg/m3 (Sk) 		NIOSH* DHHS #92-100,1992


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
ATSDR TOXICOLOGY PROFILE (NTIS** PB/95/100111/AS)
Used as stomach, contact insecticide
EPA TSCA Section 8(d) unpublished health/safety studies
On EPA IRIS database
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NIOSH Analytical Method, 1994: Chlordane, 5510
NCI Carcinogenesis Bioassay (feed);clear evidence:mouse NCITR* NCI-TR-8,1977
NCI Carcinogenesis Bioassay (feed);no evidence:rat NCITR* NCI-TR-8,1977
OSHA ANALYTICAL METHOD #67


REFERENCES:

CODEN
REFERENCE
34ZIAG "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969
85DCAI "Poisoning; Toxicology, Symptoms, Treatments," 2nd ed., Arena, J.M., Springfield, IL, C.C. Thomas, 1970
85DPAN "Wirksubstanzen der Pflanzenschutz und Schadlingsbekampfungsmittel," Perkow, W., Berlin, Verlag Paul Parey, 1971-1976
AIHOAX Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.1-2(3), 1950. For publisher information, see AEHLAU.
AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU.
AMPLAO AMA Archives of Pathology. (Chicago, IL) V.50(4)-69, 1950-60. For publisher information, see APLMAS.
APTOD9 Abstracts of Papers, Society of Toxicology. Annual Meetings. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802)
ARSIM* Agricultural Research Service, USDA Information Memorandum. (Beltsville, MD 20705)
ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974-
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
BJPCBM British Journal of Pharmacology. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants. RG21 2XS, UK) V.34- 1968-
BNYMAM Bulletin of the New York Academy of Medicine. (New York Academy of Medicine, 2 E. 103rd St., New York, NY 10029) Ser 2: V.1- 1925-
CBINA8 Chemico-Biological Interactions. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1969-
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402)
CLPTAT Clinical Pharmacology and Therapeutics. (American Society for Clinical Pharmacology and Therapeutics, St. Louis Mo Mosby-Year Book) V.1- 1960-
CMEP** "Clinical Memoranda on Economic Poisons," U.S. Dept. HEW, Public Health Service, Communicable Disease Center, Atlanta, GA, 1956
CNDQA8 Cahiers de Nutrition et de Dietetique. (Editions Meteore, 42, rue du Louvre, 75001 Paris, France) V.1- 1966-
CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980-
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010)
CTOXAO Clinical Toxicology. (New York, NY) V.1-18, 1968-81. For publisher information, see JTCTDW.
DOEAAH Down to Earth. (Dow Chemical USA, Agricultural Products Dept., Midland, MI 48640) V.1- 1945-
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
EJTXAZ European Journal of Toxicology and Environmental Hygiene. (Paris, France) V.7-9, 1974-76. For publisher information, see TOERD9.
ENDOAO Endocrinology (Baltimore). (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21203) V.1- 1917-
ENVRAL Environmental Research. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1967-
FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936-
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972-
IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979-
JAVMA4 Journal of the American Veterinary Medical Association. (American Veterinary Medical Assoc., 930 N. Meacham Rd., Schaumburg, IL 60196) V.48- 1915-
JEPTDQ Journal of Environmental Pathology and Toxicology. (Park Forest South, IL) V.1-5(3), 1977-81(?). For publisher information, see JEPOEC.
JTCTDW Journal of Toxicology, Clinical Toxicology. (Marcel Dekker, 270 Madison Ave., New York, NY 10016) V.19- 1982-
JTEHD6 Journal of Toxicology and Environmental Health. (Hemisphere Pub., 1025 Vermont Ave., NW, Washington, DC 20005) V.1- 1975/76-
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964-
NCITR* National Cancer Institute Carcinogenesis Technical Report Series. (Bethesda, MD) No.0-205. For publisher information, see NTPTR*.
NIOSH* National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda.
PCOC** Pesticide Chemicals Official Compendium, Association of the American Pesticide Control Officials, Inc., 1966. (Topeka, KS)
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968-
RBREV* Status of Pesticides in Registration, Reregistration, and Special Review (Rainbow Report), Special Review and Reregistration Division Office of Pesticide Programs U.S. Environmental Protection Agency, 401 M. Street, S.W., Washington, D.C. 20460, Spring 1998
RREVAH Residue Reviews. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1962-
TAEHC* Environmental Health Criteria (United Nations Environment Programme. Geneva, World Health Organization) 1- 1976-
TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968-
TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977-
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959-
VCVGH* "Vrednie chemichescie veshestva, galogenproisvodnie uglevodorodov". (Hazardous substances: Galogenated hydrocarbons) Bandman A.L. et al., Chimia, 1990.
YKYUA6 Yakkyoku. Pharmacy. (Nanzando, 4-1-11, Yushima, Bunkyo-ku, Tokyo, Japan) V.1- 1950-

Used as stomach, contact insecticide

RTECS Compound Description:
   Agricultural Chemical
   Tumorigen
   Mutagen
   Reproductive Effector
   Human Data

ALT CAS #: 39400-80-1
ALT CAS #: 53637-13-1
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