The Registry of Toxic Effects of Chemical Substances

Methane, trifluoro -

RTECS #: PB6900000

CAS #: 75-46-7

UPDATE: October 1997 MW: 70.02 MF: CHF3


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. MUTATION DATA:
  3. NIOSH DOCUMENTATION AND SURVEILLANCE:
  4. STATUS IN FEDERAL AGENCIES:
  5. REFERENCES:

SYNONYMS:

  1. Arcton 1
  2. FC 23 (fluorocarbon)
  3. Fluoroform
  4. Fluoryl
  5. Freon 23
  6. Freon F - 23
  7. Freon R 23
  1. Genetron - 23
  2. Carbon trifluoride
  3. Halocarbon 23
  4. R 23
  5. R 23 (halocarbon)
  6. Methyl trifluoride
  7. Trifluoromethane


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
sex chromosome loss and nondisjunction inhalation
Drosophila melanogaster 		98 pph/10 minute ENVRAL 7,275,1974


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 82197;
Number of Industries 1;
Total Number of Facilities 11;
Number of Occupations 3;
Total Number of Employees Exposed 357
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 82197;
Number of Industries 2;
Total Number of Facilities 14;
Number of Occupations 4;
Total Number of Employees Exposed 529;
Total Number of Female Employees Exposed 353


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA GENETOX PROGRAM 1988, Inconclusive: D melanogaster Sex-linked lethal
EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used as refrigerant for very-low-temperature applications
EPA TSCA Section 8(d) unpublished health/safety studies
On EPA IRIS database
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE
ENVRAL Environmental Research. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1967-

Used as refrigerant for very-low-temperature applications

RTECS Compound Description:
   Mutagen

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