RTECS:PA7525000 The Registry of Toxic Effects of Chemical Substances | CDC/NIOSH

The Registry of Toxic Effects of Chemical Substances

Methane, dibromodifluoro -

RTECS #: PA7525000

CAS #: 75-61-6

UPDATE: November 2004 MW: 209.83 MF: CBr₂F₂

NOTE:

TOXICITY DATA HAVE NOT BEEN EVALUATED. OMISSION OF A SUBSTANCE OR NOTATION DOES NOT IMPLY ANY RELIEF FROM REGULATORY RESPONSIBILITY.

TABLE OF CONTENTS:

SYNONYMS:

ACUTE TOXICITY DATA:

REVIEWS:

STANDARDS AND REGULATIONS:

NIOSH DOCUMENTATION AND SURVEILLANCE:

STATUS IN FEDERAL AGENCIES:

REFERENCES:

SYNONYMS:

Difluorodibromomethane

Difluorodibromomethane (ACGIH:OSHA)

Freon 12 - B2

Halon 1202

SKIN AND EYE IRRITATION DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

MUTATION DATA AND REFERENCES:
SYSTEM TEST ROUTE/
ORGANISM/
TISSUE DOSE REFERENCE
N/R N/R N/R N/R

REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

TUMORIGENIC DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
inhalation
mouse lethal concentration (50 percent kill): 140 gm/m³/2 hour Behavioral: Rigidity (includes catalepsy)

Liver: Other changes

Kidney, Ureter, and Bladder: Other changes TLSMA6 111,10,1975
inhalation
mouse lethal concentration (50 percent kill): 259,200 mg/m³/2 hour N/R VCVGH* -,623,1990
inhalation
rat lethal concentration (50 percent kill): 210,600 mg/m³/4 hour N/R VCVGH* -,623,1990
inhalation
rat lowest published lethal concentration: 470,000 mg/m³/15 minute N/R VCVGH* -,623,1990

OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

REVIEWS:
ORGANIZATION STANDARD
REFERENCE

American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 100 ppm DTLVS* TLV/BEI,2003

STANDARDS AND REGULATIONS:
ORGANIZATION STANDARD
REFERENCE

Mine Safety and Health Administration (MSHA) STANDARD - air time-weighted average 100 ppm (860 mg/m³) DTLVS* 3,86,1971
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) 8 hour time-weighted average 100 ppm (860 mg/m³) CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) 8 hour time-weighted average 100 ppm (860 mg/m³) CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) 8 hour time-weighted average 100 ppm (860 mg/m³) CFRGBR 29,1915.1000,1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors) 8 hour time-weighted average 100 ppm (860 mg/m³) CFRGBR 41,50-204.50,1994
Occupational Exposure Limit - AUSTRALIA time-weighted average 100 ppm (860 mg/m³), JAN1993
Occupational Exposure Limit - AUSTRIA MAK 100 ppm (860 mg/m³), JAN1999
Occupational Exposure Limit - BELGIUM time-weighted average 100 ppm (858 mg/m³), JAN1993
Occupational Exposure Limit - DENMARK time-weighted average 100 ppm (860 mg/m³), JAN1999
Occupational Exposure Limit - FINLAND time-weighted average 100 ppm (860 mg/m³), short term exposure limit 150 ppm (1290 mg/m³), JAN1999
Occupational Exposure Limit - FRANCE VME 100 ppm (860 mg/m³), JAN1993
Occupational Exposure Limit - GERMANY MAK 100 ppm (860 mg/m³), JAN1999
Occupational Exposure Limit - THE NETHERLANDS MAC-TGG 860 mg/m³, 2003
Occupational Exposure Limit - THE PHILIPPINES time-weighted average 100 ppm (860 mg/m³), JAN1993
Occupational Exposure Limit - SWITZERLAND MAK- week 100 ppm (860 mg/m³), KZG- week 200 ppm (1720 mg/m³), JAN1999
Occupational Exposure Limit - TURKEY time-weighted average 100 ppm (860 mg/m³), JAN1993
Occupational Exposure Limit - UNITED KINGDOM time-weighted average 100 ppm (872 mg/m³), short term exposure limit 150 ppm, SEP2000
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN, KOREA American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

time-weighted average 100 ppm
Occupational Exposure Limit IN NEW ZEALAND, SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
time-weighted average 100 ppm

NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION STANDARD or SURVEY
REFERENCE

National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO DIFLUORODIBROMOMETHANE-air 10 hour time-weighted average 100 ppm NIOSH* DHHS #92-100,1992
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 25515;
Number of Industries 2;
Total Number of Facilities 40;
Number of Occupations 3;
Total Number of Employees Exposed 2,234
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 25515;
Number of Industries 1;
Total Number of Facilities 7;
Number of Occupations 1;
Total Number of Employees Exposed 28

STATUS IN FEDERAL AGENCIES:
ORGANIZATION
REFERENCE

EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NIOSH Analytical Method, 1994: Difluorodibromomethane, 1012

REFERENCES:
CODEN
REFERENCE

CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402)
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
NIOSH* National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda.
TLSMA6 Trudy Leningradskogo Sanitarno-Gigienicheskogo Meditsinskogo Instituta. (Leningrad, Russia) V.1-145, 1949-82. Discontinued.
VCVGH* "Vrednie chemichescie veshestva, galogenproisvodnie uglevodorodov". (Hazardous substances: Galogenated hydrocarbons) Bandman A.L. et al., Chimia, 1990.

Click Here for Additional Information about RTECS