The Registry of Toxic Effects of Chemical Substances

Mercury (I) chloride

RTECS #: OV8750000

CAS #: 7546-30-7

UPDATE: May 2004 MW: 236.04 MF: ClHg


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. MUTATION DATA:
  3. OTHER MULTIPLE DOSE DATA:
  4. REVIEWS:
  5. STANDARDS AND REGULATIONS:
  6. NIOSH DOCUMENTATION AND SURVEILLANCE:
  7. STATUS IN FEDERAL AGENCIES:
  8. REFERENCES:

SYNONYMS:

  1. Chlorure mercureux (French)
  2. C.I. 77764
  3. Cloruro di mercurio (Italian)
  4. Cloruro mercuroso (Italian)
  5. Calosan
  6. Cyclosan
  7. Mercurochloride (Dutch)
  1. Mercurous chloride
  2. Mercury monochloride
  3. Mercury protochloride
  4. Quecksilber (I) - chlorid (German)
  5. Quecksilber chloruer (German)
  6. Mild mercury chloride
  7. Precipite blanc


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
DNA repair Bacillus subtilis 50 mmol/L MUREAV 77,109,1980
other mutation test systems hamster ovary 2,700 µg/L MUREAV 290,281,1993
sister chromatid exchange hamster ovary 3,200 nmol/L ENMUDM 7,381,1985


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
oral
rabbit 		lowest published toxic dose: 1,120 mg/kg/8 week- intermittent Brain and Coverings: Other degenerative changes

Liver: Fatty liver degeneration

Kidney, Ureter, and Bladder: Changes in tubules (including acute renal failure, acute tubular necrosis) 		VCVN1* -,181,1988


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 0.025 mg(Hg)/m3 (skin) DTLVS* TLV/BEI,1999
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value Not classifiable as a human carcinogen DTLVS* TLV/BEI,1999
TOXICOLOGY REVIEW
SDGTB3 1,177,1971
TOXICOLOGY REVIEW
RREVAH 42,103,1972


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
Mine Safety and Health Administration (MSHA) STANDARD - air time-weighted average 0.05 mg(Hg)/m3 DTLWS* 3,22,1973
Occupational Exposure Limit - AUSTRALIA time-weighted average 0.05 mg(Hg)/m3, Skin, JAN1993
Occupational Exposure Limit - BELGIUM time-weighted average 0.05 mg(Hg)/m3, Skin, JAN1993
Occupational Exposure Limit - DENMARK time-weighted average 0.05 mg(Hg)/m3, Skin, JAN1999
Occupational Exposure Limit - FINLAND time-weighted average 1 mg(Hg)/m3, JAN1999
Occupational Exposure Limit - FRANCE VME 0.1 mg(Hg)/m3, JAN1999
Occupational Exposure Limit - GERMANY MAK 0.01 ppm (0.1 mg(Hg)/m3), JAN1999
Occupational Exposure Limit - HUNGARY time-weighted average 0.02 mg(Hg)/m3, short term exposure limit 0.04 mg(Hg)/m3, JAN1993
Occupational Exposure Limit - JAPAN Occupational Exposure Limit 0.05 mg(Hg)/m3, JAN1999
Occupational Exposure Limit - NORWAY time-weighted average 0.05 mg(Hg)/m3, JAN1999
Occupational Exposure Limit - POLAND MAC(time-weighted average) 0.05 mg(Hg)/m3, MAC(short term exposure limit) 0.15 mg(Hg)/m3, JAN1999
Occupational Exposure Limit - RUSSIA time-weighted average 0.05 mg(Hg)/m3, short term exposure limit 0.01 mg(Hg)/m3, JAN1993
Occupational Exposure Limit - SWEDEN NGV 0.05 mg(Hg)/m3, Skin, JAN1999
Occupational Exposure Limit - THAILAND short term exposure limit 0.05 mg(Hg)/m3, JAN1993
Occupational Exposure Limit - UNITED KINGDOM LTEL 0.05 mg(Hg)/m3, short term exposure limit 0.15 mg(Hg)/m3, JAN1993
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN, KOREA American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

Not classifiable as a human carcinogen
Occupational Exposure Limit IN NEW ZEALAND, SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
Not classifiable as a human carcinogen


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO MERCURY, ARYL AND INORGANIC-air ceiling concentration 0.1 mg/m3 (Sk) NIOSH* DHHS #92-100,1992


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA GENETOX PROGRAM 1988, Positive: B subtilis rec assay
EPA GENETOX PROGRAM 1988, Inconclusive: B subtilis rec assay
EPA TSCA Section 8(b) CHEMICAL INVENTORY


REFERENCES:

CODEN
REFERENCE
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
DTLWS* "Documentation of the Threshold Limit Values for Substances in Workroom Air," Supplements. For publisher information, see 85INA8.
ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG.
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964-
NIOSH* National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda.
RREVAH Residue Reviews. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1962-
SDGTB3 Seminars in Drug Treatment. (New York, NY) V.1-3, 1971-74. Discontinued.
VCVN1* "Vrednie chemichescie veshestva. Neorganicheskie soedinenia elementov I-IV groopp" (Hazardous substances. Inornanic substances containing I-IV group elements), Filov V.A., Chimia, 1988.

Used as a turf fungicide to control brown patch and dollar spot

FDA-over the counter drug

RTECS Compound Description:
   Agricultural Chemical
   Mutagen

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