The Registry of Toxic Effects of Chemical Substances
Mercury chloride |
UPDATE: August 2003 | MW: 472.08 | MF: Cl2Hg2 |
SYNONYMS:
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SKIN AND EYE IRRITATION DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
|
N/R |
N/R
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N/R
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N/R
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MUTATION DATA AND REFERENCES:
SYSTEM TEST
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ROUTE/ | ORGANISM/ TISSUE
DOSE
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REFERENCE
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cytogenetic analysis
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hamster
embryo
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30 µmol/well /6 hour
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TIVIEQ 15,463,2001
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REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
N/R |
N/R
|
N/R
|
N/R
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TUMORIGENIC DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
N/R |
N/R
|
N/R
|
N/R
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ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
intraperitoneal | mouse
lethal dose (50 percent kill): 10 mg/kg
|
N/R
|
GTPZAB 25(7),27,1981
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oral | mouse
lethal dose (50 percent kill): 180 mg/kg
|
N/R
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GTPZAB 25(7),27,1981
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oral | mouse
lowest published toxic dose: 7.08 mg/kg
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Nutritional and Gross Metabolic: Changes in: Other metals
|
FCTOD7 39,571,2001
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oral | rat
lethal dose (50 percent kill): 210 mg/kg
|
N/R
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PEMNDP 9,552,1991
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skin | rat
lethal dose (50 percent kill): 1,500 mg/kg
|
N/R
|
GTPZAB 25(7),27,1981
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OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
oral | mouse
lowest published toxic dose: 17,640 µg/kg/7 week- intermittent
|
Blood: Other changes | Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Dehydrogenases Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Multiple enzyme effects
TXAPA9 68,218,1983
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oral | mouse
lowest published toxic dose: 56.25 mg/kg/45 day- intermittent
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Reproductive: Paternal effects: Testes, epididymis, sperm duct | Reproductive: Effects on fertility: Male fertility index (e.g., # males impregnating females per # males exposed to fertile nonpregnant females) Related to Chronic Data: Changes in testicular weight
REPTED 15,705,2001
|
oral | rat
lowest published toxic dose: 84 mg/kg/12 week- intermittent
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Kidney, Ureter, and Bladder: Proteinuria | Kidney, Ureter, and Bladder: Other changes in urine composition Blood: Changes in serum composition (e.g. TP, bilirubin, cholesterol)
GTPZAB 35(9),27,1991
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oral | rat
lowest published toxic dose: 40.5 mg/kg/81 day- intermittent
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Skin: After systemic exposure: Dermatitis, other | Kidney, Ureter, and Bladder: Changes in kidney weight Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field
FCTOD7 39,73,2001
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oral | rat
lowest published toxic dose: 81 mg/kg/81 day- intermittent
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Reproductive: Paternal effects: Prostate, seminal vesicle, Cowper's gland, accessory glands
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FCTOD7 39,73,2001
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oral | rat
lowest published toxic dose: 121.5 mg/kg/81 day- intermittent
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Nutritional and Gross Metabolic: Weight loss or decreased weight gain
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FCTOD7 39,73,2001
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oral | rat
lowest published toxic dose: 59.3 mg/kg/79 day- intermittent
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Skin: After systemic exposure: Dermatitis, other | Liver: Changes in liver weight Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field
FCTOD7 39,73,2001
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oral | rat
lowest published toxic dose: 197.5 mg/kg/79 day- intermittent
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Nutritional and Gross Metabolic: Weight loss or decreased weight gain
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FCTOD7 39,73,2001
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REVIEWS:
ORGANIZATION
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STANDARD
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REFERENCE
N/R
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N/R
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N/R
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STANDARDS AND REGULATIONS:
ORGANIZATION
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STANDARD
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REFERENCE
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1988
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PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION
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FEREAC 54,7740,1989
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Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF
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PESTICIDES: Cancelled
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RBREV* -,262,1998
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NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION
|
STANDARD or SURVEY
|
|
REFERENCE
N/R
|
N/R
|
N/R
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STATUS IN FEDERAL AGENCIES:
ORGANIZATION
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REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
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Used as an insecticide and fungicide
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EPA TSCA Section 8(d) unpublished health/safety studies
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EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
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REFERENCES:
CODEN
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REFERENCE
FCTOD7
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Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford,
NY 10523) V.20- 1982-
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FEREAC
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Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402)
V.1- 1936-
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GTPZAB
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Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see
MTPEEI
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PEMNDP
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Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4
7QG, UK) V.1- 1968-
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RBREV*
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Status of Pesticides in Registration, Reregistration, and Special Review (Rainbow Report),
Special Review and Reregistration Division Office of Pesticide Programs U.S. Environmental
Protection Agency, 401 M. Street, S.W., Washington, D.C. 20460, Spring 1998
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REPTED
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Reproductive Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY
10523) V.1- 1987-
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TIVIEQ
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Toxicology In Vitro. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523)
V.1- 1987-
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TXAPA9
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Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802)
V.1- 1959-
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