The Registry of Toxic Effects of Chemical Substances

Manganese oxide

RTECS #: OP0895000

CAS #: 1317-35-7

UPDATE: November 2004 MW: 228.82 MF: Mn3O4


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. REPRODUCTIVE EFFECTS DATA:
  3. ACUTE TOXICITY DATA:
  4. REVIEWS:
  5. STANDARDS AND REGULATIONS:
  6. STATUS IN FEDERAL AGENCIES:
  7. REFERENCES:

SYNONYMS:

  1. Manganese tetroxide (ACGIH)
  2. Manganomanganic oxide
  1. Trimanganese tetraoxide
  2. Trimanganese tetroxide


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
oral
mouse 		lowest published toxic dose: 23 gm/kg (44 day male) Reproductive: Paternal effects: Testes, epididymis, sperm duct

Reproductive: Paternal effects: Prostate, seminal vesicle, Cowper's gland, accessory glands 		JTEHD6 6,861,1980


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
inhalation
mouse 		lethal concentration : >3,608 µg/m3/2 hour N/R AIHAAP 41,494,1980
intratracheal
rat 		lowest published lethal dose: 375 mg/kg Lung, Thorax, or Respiration: Emphysema

Lung, Thorax, or Respiration: Acute pulmonary edema 		GISAAA 20(1),25,1955


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 0.2 mg(Mn)/m3 DTLVS* TLV/BEI,1999


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) ceiling concentration 5 mg(Mn)/m3 CFRGBR 29,1915.1000,1993
Occupational Exposure Limit - AUSTRALIA time-weighted average 5 mg(Mn)/m3, JAN1993
Occupational Exposure Limit - AUSTRIA MAK 1 mg/m3, JAN1999
Occupational Exposure Limit - BELGIUM time-weighted average 5 mg(Mn)/m3, JAN1993
Occupational Exposure Limit - DENMARK time-weighted average 2.5 mg(Mn)/m3, JAN1999
Occupational Exposure Limit - FINLAND time-weighted average 0.5 mg(Mn)/m3, JAN1999
Occupational Exposure Limit - FRANCE VME 1 mg/m3, JAN1999
Occupational Exposure Limit - GERMANY MAK 0.5 mg(Mn)/m3, JAN1999
Occupational Exposure Limit - HUNGARY time-weighted average 0.3 mg(Mn)/m3, short term exposure limit 0.6 mg(Mn)/m3, JAN1993
Occupational Exposure Limit - THE NETHERLANDS MAC-TGG 1 mg/m3, 2003
Occupational Exposure Limit - NORWAY time-weighted average 2.5 mg(Mn)/m3, JAN1999
Occupational Exposure Limit - POLAND MAC(time-weighted average) 0.3 mg(Mn)/m3, MAC( continuous) 5 mg(Mn)/m3, JAN1999
Occupational Exposure Limit - SWEDEN NGV 1 mg(Mn)/m3, TGV 2.5 mg(Mn)/m3 (resp. dust), JAN1993
Occupational Exposure Limit - SWEDEN NGV 2.5 mg(Mn)/m3, TGV 5 mg(Mn)/m3 (total dust), JAN1993
Occupational Exposure Limit - SWITZERLAND MAK- week 1 mg/m3, JAN1999
Occupational Exposure Limit - UNITED KINGDOM time-weighted average 1 mg/m3, SEP2000
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN, KOREA American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

time-weighted average 0.2 mg(Mn)/m3
Occupational Exposure Limit IN NEW ZEALAND, SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
time-weighted average 0.2 mg(Mn)/m3


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
N/R N/R N/R


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE
AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958-
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402)
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
JTEHD6 Journal of Toxicology and Environmental Health. (Hemisphere Pub., 1025 Vermont Ave., NW, Washington, DC 20005) V.1- 1975/76-

RTECS Compound Description:
   Reproductive Effector

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