The Registry of Toxic Effects of Chemical Substances

Lithium

RTECS #: OJ5540000

CAS #: 7439-93-2

UPDATE: August 2004 MW: 6.94 MF: Li


NOTE:

TABLE OF CONTENTS:
  1. MUTATION DATA:
  2. ACUTE TOXICITY DATA:
  3. REVIEWS:
  4. NIOSH DOCUMENTATION AND SURVEILLANCE:
  5. STATUS IN FEDERAL AGENCIES:
  6. REFERENCES:

SYNONYMS:

N/R N/R


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
cytogenetic analysis unreported route
human 		714 mg/kg/8 week- intermittent LANCAO 2,435,1969


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
intraperitoneal
mouse 		lethal dose (50 percent kill): 1 gm/kg N/R 85IXA4 -,704,1948


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
TOXICOLOGY REVIEW
ARPTDI 16,231,1976
TOXICOLOGY REVIEW
KDYIA5 10,82,1976
TOXICOLOGY REVIEW
QJMEA7 47,123,1978
TOXICOLOGY REVIEW
CNMEAH 54,115,1990
TOXICOLOGY REVIEW
JTCTDW 39,4,2001
TOXICOLOGY REVIEW
CTOXAO 39,381,2001


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 80295;
Number of Industries 8;
Total Number of Facilities 372;
Number of Occupations 11;
Total Number of Employees Exposed 1,942
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 80295;
Number of Industries 8;
Total Number of Facilities 207;
Number of Occupations 11;
Total Number of Employees Exposed 3,455;
Total Number of Female Employees Exposed 1,084


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used in inorganic syntheses
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NIOSH Analytical Method, 1994: Elements in blood or tissue, 8005
OSHA ANALYTICAL METHOD #ID121


REFERENCES:

CODEN
REFERENCE
85IXA4 "Structure et Activite Pharmacodyanmique des Medicaments du Systeme Nerveux Vegetatif," Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948
ARPTDI Annual Review of Pharmacology and Toxicology. (Annual Reviews, Inc., POB 10139, Palo Alto, CA 94303) V.16- 1976-
CNMEAH Connectical Medicine. (Connecticul State Medical Society, 160 St. Ronan Street, New Heaven, Conn. 06511) V.22 n8- 1958-
CTOXAO Clinical Toxicology. (New York, NY) V.1-18, 1968-81. For publisher information, see JTCTDW.
JTCTDW Journal of Toxicology, Clinical Toxicology. (Marcel Dekker, 270 Madison Ave., New York, NY 10016) V.19- 1982-
KDYIA5 Kidney International. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus Secaucus, NJ 07094) V.1- 1972-
LANCAO Lancet. (7 Adam St., London WC2N 6AD, UK) V.1- 1823-
QJMEA7 Quarterly Journal of Medicine. (Oxford Univ. Press, Walton St., Oxford OX2 6DP, UK) V.1- 1932-

Used in inorganic syntheses

NIOSH PROFILE (HEAVY METAL GREASES AND SOAPS), SRI, 2/77

NIOSH PROFILE (LITHIUM AND ITS COMPOUNDS), SRC, 4/78

RTECS Compound Description:
   Drug
   Mutagen
   Reproductive Effector

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