The Registry of Toxic Effects of Chemical Substances

Lead tetroxide

RTECS #: OG5425000

CAS #: 1314-41-6

UPDATE: May 2005 MW: 685.57 MF: O4Pb3


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. ACUTE TOXICITY DATA:
  3. REVIEWS:
  4. STANDARDS AND REGULATIONS:
  5. NIOSH DOCUMENTATION AND SURVEILLANCE:
  6. STATUS IN FEDERAL AGENCIES:
  7. REFERENCES:

SYNONYMS:

  1. C.I. 77578
  2. C.I. Pigment Red 105
  3. Gold satinobre
  4. Heuconin 5
  5. Lead orthoplumbate
  6. Lead oxide (3:4)
  7. Lead oxide (Pb3O4)
  8. Lead Oxide Red
  9. Lead tetraoxide
  10. Mennige
  11. Mineral Orange
  12. Mineral Red
  1. Minium
  2. Minium Non - Setting RL 95
  3. Orange Lead
  4. Paris Red
  5. Pigment Red 105
  6. Plumboplumbic oxide
  7. Red Lead
  8. Red Lead Oxide
  9. Sandix
  10. Saturn Red
  11. Trilead tetraoxide
  12. Trilead tetroxide


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
intraperitoneal
guinea pig 		lethal dose (50 percent kill): 220 mg/kg N/R 85KYAH 11,854,1989
intraperitoneal
mouse 		lethal dose (50 percent kill): 17,700 mg/kg N/R GTPZAB 26(8),51,1982
intraperitoneal
rat 		lethal dose (50 percent kill): 630 mg/kg N/R GTPZAB 19(3),30,1975
oral
guinea pig 		lowest published lethal dose: 1 gm/kg Behavioral: Convulsions or effect on seizure threshold

Blood: Pigmented or nucleated red blood cells 		AHBAAM 125,273,1941


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 0.05 mg(Pb)/m3; animal carcinogen DTLVS* TLV/BEI,1999
TOXICOLOGY REVIEW
85DHAX Pb,254,1972


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
Occupational Exposure Limit - ARAB Republic of Egypt time-weighted average 0.05 mg(Pb)/m3, JAN1993
Occupational Exposure Limit - AUSTRALIA time-weighted average 0.15 mg(Pb)/m3, JAN1993
Occupational Exposure Limit - AUSTRIA MAK 0.1 mg(Pb)/m3, JAN1993
Occupational Exposure Limit - BELGIUM time-weighted average 0.15 mg(Pb)/m3, JAN1993
Occupational Exposure Limit - DENMARK time-weighted average 0.1 mg(Pb)/m3, JAN1999
Occupational Exposure Limit - FINLAND time-weighted average 0.1 mg(Pb)/m3, JAN1999
Occupational Exposure Limit - FRANCE VME 0.15 mg(Pb)/m3, JAN1999
Occupational Exposure Limit - GERMANY MAK 0.1 mg(Pb)/m3, JAN1999
Occupational Exposure Limit - HUNGARY short term exposure limit 0.04 mg(Pb)/m3, Carcinogen, JAN1993
Occupational Exposure Limit - JAPAN Occupational Exposure Limit 0.1 mg(Pb)/m3, JAN1999
Occupational Exposure Limit - NORWAY time-weighted average 0.05 mg(Pb)/m3, JAN1999
Occupational Exposure Limit - THE PHILIPPINES time-weighted average 0.15 mg(Pb)/m3, JAN1993
Occupational Exposure Limit - POLAND MAC(time-weighted average) 0.05 mg(Pb)/m3, JAN1999
Occupational Exposure Limit - RUSSIA short term exposure limit 0.005 ppm (0.01 mg(Pb)/m3), JAN1993
Occupational Exposure Limit - SWEDEN NGV 0.05 mg(Pb)/m3 (resp. dust), JAN1999
Occupational Exposure Limit - SWEDEN NGV 0.1 mg(Pb)/m3 (total dust), JAN1999
Occupational Exposure Limit - SWITZERLAND MAK- week 0.1 mg(Pb)/m3, JAN1999
Occupational Exposure Limit - THAILAND time-weighted average 0.2 mg(Pb)/m3, JAN1993
Occupational Exposure Limit - TURKEY time-weighted average 0.2 mg(Pb)/m3, JAN1993
Occupational Exposure Limit - UNITED KINGDOM LTEL 0.15 mg(Pb)/m3, JAN1993


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO LEAD, INORGANIC-air 10 hour time-weighted average <0.1 mg(Pb)/m3 NIOSH* DHHS #92-100,1992
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: M0126;
Number of Industries 41;
Total Number of Facilities 2,103;
Number of Occupations 36;
Total Number of Employees Exposed 28,875
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: M0126;
Number of Industries 20;
Total Number of Facilities 1,687;
Number of Occupations 23;
Total Number of Employees Exposed 18,022;
Total Number of Female Employees Exposed 1,630


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used as corrosion-inhibiting pigment in primers and paints and in making storage batteries
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NTP 11th Report on Carcinogens,2004:Reasonably anticipated to be a human carcinogen


REFERENCES:

CODEN
REFERENCE
85DHAX "Medical and Biologic Effects of Environmental Pollutants Series," Washington, DC, National Academy of Sciences, 1972-77
85KYAH "Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals", 11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989
AHBAAM Archiv fuer Hygiene und Bakteriologie. (Munich, Fed. Rep. Ger.) V.101-154, 1929-71. For publisher information, see ZHPMAT.
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI
NIOSH* National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda.

Used as corrosion-inhibiting pigment in primers and paints and in making storage batteries

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