The Registry of Toxic Effects of Chemical Substances

Isopentyl alcohol, acetate

RTECS #: NS9800000

CAS #: 123-92-2

UPDATE: May 2004 MW: 130.21 MF: C7H14O2


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. ACUTE TOXICITY DATA:
  3. REVIEWS:
  4. STANDARDS AND REGULATIONS:
  5. NIOSH DOCUMENTATION AND SURVEILLANCE:
  6. STATUS IN FEDERAL AGENCIES:
  7. REFERENCES:

SYNONYMS:

  1. Acetic acid, isopentyl ester
  2. Banana oil
  3. Isoamyl acetate (ACGIH:OSHA)
  4. Isoamylester kyseliny octove (Czech)
  5. Isopentyl acetate
  6. Isoamyl ethanoate
  1. 3 - Methyl - 1 - butanol acetate
  2. 3 - Methylbutyl acetate
  3. 3 - Methyl - 1 - butyl acetate
  4. 3 - Methylbutyl ethanoate
  5. Pear oil


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
inhalation
cat 		lowest published lethal concentration: 35 gm/m3 Behavioral: General anesthetic

Behavioral: Food intake (animal)

Kidney, Ureter, and Bladder: Proteinuria 		AGGHAR 5,1,1933
oral
rat 		lethal dose (50 percent kill): 16,600 mg/kg N/R YKYUA6 32,1241,1981
oral
rabbit 		lethal dose (50 percent kill): 7,422 mg/kg N/R IMSUAI 41,31,1972
subcutaneous
guinea pig 		lowest published lethal dose: 5 gm/kg Peripheral Nerve and Sensation: Spastic paralysis with/without sensory change

Behavioral: General anesthetic 		AGGHAR 5,1,1933
skin
rabbit 		lethal dose (50 percent kill): >5 gm/kg N/R NTIS** OTS0573010


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 50 ppm DTLVS* TLV/BEI,2002
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 50 ppm; short term exposure limit 100 ppm DTLVS* TLV/BEI,1999
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value short term exposure limit 100 ppm DTLVS* TLV/BEI,2002


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
Mine Safety and Health Administration (MSHA) STANDARD - air time-weighted average 100 ppm (525 mg/m3) DTLVS* 3,138,1971
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) 8 hour time-weighted average 100 ppm (525 mg/m3) CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) 8 hour time-weighted average 100 ppm (525 mg/m3) CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) 8 hour time-weighted average 100 ppm (525 mg/m3) CFRGBR 29,1915.1000,1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors) 8 hour time-weighted average 100 ppm (525 mg/m3) CFRGBR 41,50-204.50,1994
Occupational Exposure Limit - AUSTRALIA time-weighted average 100 ppm (525 mg/m3), JAN1993
Occupational Exposure Limit - BELGIUM time-weighted average 100 ppm (532 mg/m3), JAN1993
Occupational Exposure Limit - DENMARK time-weighted average 100 ppm (525 mg/m3), JAN1999
Occupational Exposure Limit - FRANCE VME 100 ppm (525 mg/m3), JAN1999
Occupational Exposure Limit - JAPAN Occupational Exposure Limit 100 ppm (530 mg/m3), JAN1999
Occupational Exposure Limit - NORWAY time-weighted average 50 ppm (260 mg/m3), JAN1999
Occupational Exposure Limit - THE PHILIPPINES time-weighted average 100 ppm (525 mg/m3), JAN1993
Occupational Exposure Limit - RUSSIA time-weighted average 100 ppm, JAN1993
Occupational Exposure Limit - SWITZERLAND MAK- week 50 ppm (270 mg/m3), Skin, JAN1999
Occupational Exposure Limit - UNITED KINGDOM LTEL 100 ppm (525 mg/m3), short term exposure limit 125 ppm, JAN1993
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN, KOREA American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

short term exposure limit 100 ppm
Occupational Exposure Limit IN NEW ZEALAND, SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
short term exposure limit 100 ppm


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO ISOAMYL ACETATE-air 10 hour time-weighted average 100 ppm NIOSH* DHHS #92-100,1992
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 40370;
Number of Industries 93;
Total Number of Facilities 11,016;
Number of Occupations 75;
Total Number of Employees Exposed 96,405
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 40370;
Number of Industries 62;
Total Number of Facilities 7,677;
Number of Occupations 79;
Total Number of Employees Exposed 97,668;
Total Number of Female Employees Exposed 32,512


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NIOSH Analytical Method, 1994: Esters I, 1450


REFERENCES:

CODEN
REFERENCE
AGGHAR Archiv fuer Gewerbepathologie und Gewerbehygiene. (Berlin, Ger.) V.1-18, 1930-61. For publisher information, see IAEHDW.
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402)
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
IMSUAI Industrial Medicine and Surgery. (Northbrook, IL) V.18-42, 1949-73. For publisher information, see IOHSA5.
NIOSH* National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda.
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
YKYUA6 Yakkyoku. Pharmacy. (Nanzando, 4-1-11, Yushima, Bunkyo-ku, Tokyo, Japan) V.1- 1950-

NIOSH PROFILE (ACETATES), SRI, 2/77

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