The Registry of Toxic Effects of Chemical Substances
1 - Hexene |
UPDATE: August 2004 | MW: 84.18 | MF: C6H12 |
SYNONYMS:
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SKIN AND EYE IRRITATION DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
|
N/R |
N/R
|
N/R
|
N/R
|
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MUTATION DATA AND REFERENCES:
SYSTEM TEST
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ROUTE/ | ORGANISM/ TISSUE
DOSE
|
REFERENCE
|
N/R
|
N/R
|
N/R
|
N/R
|
|
REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
N/R |
N/R
|
N/R
|
N/R
|
|
TUMORIGENIC DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
N/R |
N/R
|
N/R
|
N/R
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ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
inhalation | rat
lethal concentration (50 percent kill): 32,000 ppm/4 hour
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Behavioral: General anesthetic | Behavioral: Somnolence (general depressed activity) Lung, Thorax, or Respiration: Other changes
NTIS** OTS0535205
|
oral | rat
lethal dose : >10 gm/kg
|
N/R
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NTIS** OTS0535205
|
skin | rabbit
lethal dose : >10 gm/kg
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Skin and Appendages: Other: Hair
|
NTIS** OTS0535205
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OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
oral | rat
lowest published toxic dose: 43 gm/kg/43 day- intermittent
|
Kidney, Ureter, and Bladder: Changes in tubules (including acute renal failure, acute tubular necrosis)
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DCTODJ 23,327,2000
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REVIEWS:
ORGANIZATION
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STANDARD
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REFERENCE
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
|
time-weighted average 50 ppm
|
DTLVS* TLV/BEI,2003
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TOXICOLOGY REVIEW
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MUREAV 539,77,2003
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STANDARDS AND REGULATIONS:
ORGANIZATION
|
STANDARD
|
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REFERENCE
N/R
|
N/R
|
N/R
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NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION
|
STANDARD or SURVEY
|
|
REFERENCE
N/R
|
N/R
|
N/R
|
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STATUS IN FEDERAL AGENCIES:
ORGANIZATION
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REFERENCE
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
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REFERENCES:
CODEN
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REFERENCE
DCTODJ
|
Drug and Chemical Toxicology. (Marcel Dekker, 270 Madison Ave., New York, NY 10016) V.1-
1977/78-
|
DTLVS*
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The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by
American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
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MUREAV
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Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1-
1964-
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NTIS**
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National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse
for Scientific & Technical Information.
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