The Registry of Toxic Effects of Chemical Substances

2 - Heptanol

RTECS #: MJ2975000

CAS #: 543-49-7

UPDATE: February 2003 MW: 116.23 MF: C7H16O


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. ACUTE TOXICITY DATA:
  3. OTHER MULTIPLE DOSE DATA:
  4. STATUS IN FEDERAL AGENCIES:
  5. REFERENCES:

SYNONYMS:

  1. Amyl methyl carbinol
  2. Heptanol - 2
  3. s - Heptyl alcohol
  4. 2 - Heptyl alcohol
  1. Methyl amyl carbinol
  2. 1 - Methylhexanol
  3. 2 - Hydroxyheptane


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
oral
rat 		lethal dose (50 percent kill): 2,580 mg/kg N/R AMIHBC 10,61,1954
oral
rat 		lethal dose (50 percent kill): 2,600 mg/kg Behavioral: Ataxia

Behavioral: Irritability

Lung, Thorax, or Respiration: Dyspnea 		VCVGK* -,113,1984
skin
rabbit 		lethal dose (50 percent kill): 1,780 µL/kg N/R AMIHBC 10,61,1954
skin
rabbit 		lethal dose (50 percent kill): 1,800 mg/kg Behavioral: Ataxia

Behavioral: Irritability

Lung, Thorax, or Respiration: Dyspnea 		VCVGK* -,113,1984


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
inhalation
mammal (species unspecified) 		lowest published toxic concentration: 180 mg/m3/2 hour/137 day- intermittent Lung, Thorax, or Respiration: Other changes

Liver: Other changes

Kidney, Ureter, and Bladder: Other changes 		VCVGK* -,113,1994
inhalation
mammal (species unspecified) 		lowest published toxic concentration: 32 mg/m3/26 week- intermittent Brain and Coverings: Recordings from specific areas of CNS

Eye: Optic nerve neuropathy

Eye: Other eye effects 		VCVGK* -,113,1994
oral
rabbit 		lowest published toxic dose: 4.56 mg/kg/26 week- intermittent Brain and Coverings: Other degenerative changes

Liver: Other changes

Kidney, Ureter, and Bladder: Other changes 		VCVGK* -,113,1994


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
N/R N/R N/R


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY


REFERENCES:

CODEN
REFERENCE
AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU.
VCVGK* "Vrednie chemichescie veshestva, galogen I kislorod sodergashie organicheskie soedinenia". (Hazardous substances. Galogen and oxygen containing substances), Bandman A.L. et al., Chimia, 1994.

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