The Registry of Toxic Effects of Chemical Substances

Glyoxal, 40%

RTECS #: MD2700000

CAS #: 107-22-2

UPDATE: December 2000 MW: 58.04 MF: C2H2O2


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. SKIN AND EYE IRRITATION DATA:
  3. ACUTE TOXICITY DATA:
  4. NIOSH DOCUMENTATION AND SURVEILLANCE:
  5. STATUS IN FEDERAL AGENCIES:
  6. REFERENCES:

SYNONYMS:

  1. Aerotex glyoxal 40


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
eye
rabbit 		100 µL mild NTIS** OTS0535504
skin
rabbit 		258 mg open irritation test mild UCDS** 11/12/1965


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
inhalation
rat 		lethal concentration (50 percent kill): 2,410 mg/m3/4 hour Olfaction: Other olfaction effects

Lung, Thorax, or Respiration: Dyspnea 		NTIS** OTS0535127
oral
guinea pig 		lethal dose (50 percent kill): 10 gm/kg N/R NTIS** OTS0538086
oral
mouse 		lethal dose (50 percent kill): 1,280 mg/kg N/R NTIS** OTS0538086
oral
rat 		lethal dose (50 percent kill): 2,960 mg/kg Behavioral: Somnolence (general depressed activity)

Lung, Thorax, or Respiration: Respiratory depression

Nutritional and Gross Metabolic: Other changes 		NTIS** OTS0535124
oral
rabbit 		lethal dose (50 percent kill): >3,175 mg/kg N/R NTIS** OTS0538086
skin
rat 		lethal dose (50 percent kill): >2 gm/kg Skin: After systemic exposure: Dermatitis, other NTIS** OTS0535506
skin
rabbit 		lethal dose (50 percent kill): 10 mL/kg N/R UCDS** 11/12/1965


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 84477;
Number of Industries 16;
Total Number of Facilities 630;
Number of Occupations 19;
Total Number of Employees Exposed 3,846
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 84477;
Number of Industries 27;
Total Number of Facilities 2,151;
Number of Occupations 40;
Total Number of Employees Exposed 50,395;
Total Number of Female Employees Exposed 9,890


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used as intermediate for glyoxal reactant manufacture and miscellaneous specialty application
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817)

Used as intermediate for glyoxal reactant manufacture and miscellaneous specialty application

RTECS Compound Description:
   Primary Irritant

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