The Registry of Toxic Effects of Chemical Substances

Formic acid, methyl ester

RTECS #: LQ8925000

CAS #: 107-31-3

UPDATE: November 2004 MW: 60.06 MF: C2H4O2


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. ACUTE TOXICITY DATA:
  3. REVIEWS:
  4. STANDARDS AND REGULATIONS:
  5. NIOSH DOCUMENTATION AND SURVEILLANCE:
  6. STATUS IN FEDERAL AGENCIES:
  7. REFERENCES:

SYNONYMS:

  1. Formiate de methyle (French)
  2. Methyl formate
  3. Methyl formate (ACGIH:OSHA)
  4. Methyl methanoate
  5. Methyle (formiate de) (French)
  1. Methylester kyseliny mravenci (Czech)
  2. Methylformiaat (Dutch)
  3. Methylformiat (German)
  4. Metil (formiato di) (Italian)
  5. Mravencan methylnaty (Czech)


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
inhalation
rat 		lethal concentration (50 percent kill): 5,200 mg/m3/4 hour N/R NTIS** OTS0556791
oral
mouse 		lethal dose (50 percent kill): 675 mg/kg N/R NTIS** OTS0556689
oral
rat 		lethal dose (50 percent kill): 475 mg/kg N/R NTIS** OTS0556689
oral
rabbit 		lethal dose (50 percent kill): 1,622 mg/kg N/R IMSUAI 41,31,1972
skin
guinea pig 		lethal dose (50 percent kill): >20 mL/kg N/R NTIS** OTS0556689
skin
rat 		lethal dose (50 percent kill): >4 gm/kg N/R NTIS** OTS0556791
skin
rabbit 		lethal dose (50 percent kill): >5 gm/kg N/R NTIS** OTS0556797


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 100 ppm DTLVS* TLV/BEI,2002
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 100 ppm;short term exposure limit 150 ppm DTLVS* TLV/BEI,2003
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value short term exposure limit 150 ppm DTLVS* TLV/BEI,2002
TOXICOLOGY REVIEW
AMIHAB 20,517,1959


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
Mine Safety and Health Administration (MSHA) STANDARD - air time-weighted average 100 ppm (250 mg/m3) DTLVS* 3,165,1971
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) 8 hour time-weighted average 100 ppm (250 mg/m3) CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) 8 hour time-weighted average 100 ppm (250 mg/m3) CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) 8 hour time-weighted average 100 ppm (250 mg/m3) CFRGBR 29,1915.1000,1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors) 8 hour time-weighted average 100 ppm (250 mg/m3) CFRGBR 41,50-204.50,1994
Occupational Exposure Limit - AUSTRALIA time-weighted average 100 ppm (250 mg/m3), short term exposure limit 150 ppm, JAN1993
Occupational Exposure Limit - AUSTRIA MAK 100 ppm (250 mg/m3), JAN1999
Occupational Exposure Limit - BELGIUM time-weighted average 100 ppm (246 mg/m3), short term exposure limit 150 ppm (369 mg/m3), JAN1993
Occupational Exposure Limit - DENMARK time-weighted average 100 ppm (250 mg/m3), JAN1999
Occupational Exposure Limit - FINLAND time-weighted average 100 ppm (250 mg/m3), short term exposure limit 150 ppm (375 mg/m3), JAN1999
Occupational Exposure Limit - FRANCE VME 100 ppm (250 mg/m3), JAN1999
Occupational Exposure Limit - GERMANY MAK 100 ppm (250 mg/m3), JAN1999
Occupational Exposure Limit - THE NETHERLANDS MAC-TGG 250 mg/m3, 2003
Occupational Exposure Limit - SWEDEN time-weighted average 100 ppm (250 mg/m3), short term exposure limit 150 ppm (350 mg/m3), JAN1999
Occupational Exposure Limit - SWITZERLAND MAK- week 100 ppm (250 mg/m3), KZG- week 200 ppm (500 mg/m3), JAN1999
Occupational Exposure Limit - TURKEY time-weighted average 100 ppm (250 mg/m3), JAN1993
Occupational Exposure Limit - UNITED KINGDOM time-weighted average 100 ppm (250 mg/m3), short term exposure limit 150 ppm, SEP2000
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN, KOREA American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

short term exposure limit 150 ppm
Occupational Exposure Limit IN NEW ZEALAND, SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
short term exposure limit 150 ppm


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO METHYL FORMATE-air 10 hour time-weighted average 100 ppm;
short term exposure limit 150 ppm 		NIOSH* DHHS #92-100,1992
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 33850;
Number of Industries 6;
Total Number of Facilities 80;
Number of Occupations 22;
Total Number of Employees Exposed 7,738;
Total Number of Female Employees Exposed 1,402


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE
AMIHAB AMA Archives of Industrial Health. (Chicago, IL) V.11-21, 1955-60. For publisher information, see AEHLAU.
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402)
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
IMSUAI Industrial Medicine and Surgery. (Northbrook, IL) V.18-42, 1949-73. For publisher information, see IOHSA5.
NIOSH* National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda.
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.

RTECS Compound Description:
   Agricultural Chemical

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