The Registry of Toxic Effects of Chemical Substances

Ether, trichlorophenyl

RTECS #: KO4200000

CAS #: 31242-93-0

UPDATE: November 2004 MW: 376.86 MF: C12H4Cl6O


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. ACUTE TOXICITY DATA:
  3. OTHER MULTIPLE DOSE DATA:
  4. REVIEWS:
  5. STANDARDS AND REGULATIONS:
  6. NIOSH DOCUMENTATION AND SURVEILLANCE:
  7. STATUS IN FEDERAL AGENCIES:
  8. REFERENCES:

SYNONYMS:

  1. Benzene, 1,1' - oxybis - , hexachloro deriv. (9CI)
  2. Chlorinated diphenyl oxide (ACGIH:OSHA)
  3. Ether, hexachlorophenyl
  4. Hexachloro diphenyl oxide
  5. Hexachlorodiphenyl ether
  1. Phenyl ether, hexachloro deriv. (8CI)
  2. Trichloro diphenyl ether
  3. Trichloro diphenyl oxide
  4. o - Chlorinated diphenyl oxide


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
oral
rat 		lethal dose : >500 mg/kg N/R NCNSA6 5,16,1953


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
oral
rabbit 		lowest published toxic dose: 20 mg/kg/28 day- intermittent Liver: Other changes NTIS** 0TS0520721


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 0.5 mg/m3 DTLVS* TLV/BEI,2003


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
Mine Safety and Health Administration (MSHA) STANDARD - air time-weighted average 0.5 mg/m3 DTLVS* 3,45,1971
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) 8 hour time-weighted average 0.5 mg/m3 CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) 8 hour time-weighted average 0.5 mg/m3 CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) 8 hour time-weighted average 0.5 mg/m3 CFRGBR 29,1915.1000,1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors) 8 hour time-weighted average 0.5 mg/m3 CFRGBR 41,50-204.50,1994
Occupational Exposure Limit - AUSTRALIA time-weighted average 0.5 mg/m3, short term exposure limit 2 mg/m3, JAN1993
Occupational Exposure Limit - AUSTRIA MAK 0.5 mg/m3, Skin, JAN1999
Occupational Exposure Limit - BELGIUM time-weighted average 0.5 mg/m3, short term exposure limit 2 mg/m3, JAN1993
Occupational Exposure Limit - FINLAND time-weighted average 0.5 mg/m3, short term exposure limit 1.5 mg/m3, Skin, JAN1999
Occupational Exposure Limit - FRANCE CME 0.5 mg/m3, JAN1999
Occupational Exposure Limit - GERMANY MAK 0.5 mg/m3, Skin, JAN1999
Occupational Exposure Limit - NORWAY time-weighted average 0.5 mg/m3, JAN1999
Occupational Exposure Limit - THE NETHERLANDS MAC-TGG 0.5 mg/m3, 2003
Occupational Exposure Limit - SWITZERLAND MAK- week0.5 mg/m3, Skin, JAN1999
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN, KOREA American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

time-weighted average 0.5 mg/m3
Occupational Exposure Limit IN NEW ZEALAND, SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
time-weighted average 0.5 mg/m3


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO CHLORINATED DIPHENYL OXIDE-air 10 hour time-weighted average 0.5 mg/m3 NIOSH* DHHS #92-100,1992


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NIOSH Analytical Method, 1994: Chlorinated diphenyl oxide, 5025


REFERENCES:

CODEN
REFERENCE
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402)
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
NCNSA6 National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. (Washington, DC)
NIOSH* National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda.
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.

ALT CAS #: 55720-99-5
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