The Registry of Toxic Effects of Chemical Substances

Ethanol, 2 - (methylamino) -

RTECS #: KL6650000

CAS #: 109-83-1

UPDATE: December 1998 MW: 75.13 MF: C3H9NO


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. SKIN AND EYE IRRITATION DATA:
  3. ACUTE TOXICITY DATA:
  4. NIOSH DOCUMENTATION AND SURVEILLANCE:
  5. STATUS IN FEDERAL AGENCIES:
  6. REFERENCES:

SYNONYMS:

  1. N - (2 - Hydroxyethyl) - N - methylamine
  2. beta - (Methylamino) ethanol
  3. N - Methylaminoethanol
  4. 2 - Methylaminoethanol
  5. Methylethanolamine
  6. N - Methylethanolamine
  1. Methylethylolamine
  2. Methyl (beta - hydroxyethyl) amine
  3. Monomethyl - aminoaethanol (German)
  4. Monomethylaminoethanol
  5. N - Monomethylaminoethanol
  6. USAF DO - 50


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
skin
rabbit 		470 mg open irritation test mild UCDS** 1/20/1972


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
intraperitoneal
mouse 		lethal dose (50 percent kill): 125 mg/kg N/R NTIS** AD277-689
intraperitoneal
rat 		lethal dose (50 percent kill): 1,330 mg/kg N/R TXAPA9 12,486,1968
oral
rat 		lethal dose (50 percent kill): 1,391 mg/kg Eye: Chromodacryorrhea

Behavioral: Ataxia

Gastrointestinal: Hypermotility, diarrhea 		VHTODE 38,422,1996
subcutaneous
mouse 		lethal dose (50 percent kill): 1,802 mg/kg Behavioral: Convulsions or effect on seizure threshold

Behavioral: Coma

Lung, Thorax, or Respiration: Other changes 		AEPPAE 225,428,1955
skin
rabbit 		lethal dose (50 percent kill): 1,070 µL/kg Behavioral: Somnolence (general depressed activity)

Lung, Thorax, or Respiration: Other changes

Skin: After systemic exposure: Dermatitis, other 		NTIS** OTS0536158


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: X4016;
Number of Industries 36;
Total Number of Facilities 7,733;
Number of Occupations 28;
Total Number of Employees Exposed 39,013;
Total Number of Female Employees Exposed 11,887


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE
AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC.
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959-
UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817)
VHTODE Veterinary and Human Toxicology. (American College of Veterinary and Comparative Toxicology, Publication Office, Comparative Toxicology, Manhattan, KS 66506) V.19- 1977-

RTECS Compound Description:
   Primary Irritant

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