The Registry of Toxic Effects of Chemical Substances
Ethanol, 2 - (2 - (2 - ethoxyethoxy) ethoxy) - RTECS #: KK8950000
CAS #: 112-50-5
The Registry of Toxic Effects of Chemical Substances
Ethanol, 2 - (2 - (2 - ethoxyethoxy) ethoxy) - |
| UPDATE: February 2003 | MW: 178.26 | MF: C8H18O4 |
SYNONYMS:
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SKIN AND EYE IRRITATION DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
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eye | rabbit
500 mg
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mild
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AJOPAA 29,1363,1946
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MUTATION DATA AND REFERENCES:
SYSTEM TEST
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ROUTE/ | ORGANISM/ TISSUE
DOSE
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REFERENCE
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N/R
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N/R
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N/R
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N/R
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REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
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N/R |
N/R
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N/R
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N/R
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TUMORIGENIC DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
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N/R |
N/R
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N/R
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N/R
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ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
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oral | guinea pig
lethal dose (50 percent kill): 3,070 mg/kg
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N/R
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VCVGK* -,175,1984
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oral | mouse
lethal dose (50 percent kill): 5,798 mg/kg
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N/R
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VCVGK* -,175,1984
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oral | rat
lethal dose (50 percent kill): 7,750 mg/kg
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N/R
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VCVGK* -,175,1984
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skin | rabbit
lethal dose (50 percent kill): 8 mL/kg
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N/R
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AMIHBC 4,119,1951
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OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
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oral | rat
lowest published toxic dose: 141 mg/kg/26 week- intermittent
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Blood: Changes in leukocyte (WBC) count | Blood: Changes in platelet count Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: True cholinesterase
GISAAA 47(5),84,1982
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oral | rat
lowest published toxic dose: 930 mg/kg/30 day- intermittent
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Blood: Normocytic anemia | Blood: Changes in erythrocyte (RBC) count
VCVGK* -,175,1994
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oral | rat
lowest published toxic dose: 141 mg/kg/26 week- intermittent
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Blood: Changes in cell count (unspecified) | Blood: Changes in serum composition (e.g. TP, bilirubin, cholesterol) Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Multiple enzyme effects
VCVGK* -,175,1994
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REVIEWS:
ORGANIZATION
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STANDARD
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REFERENCE
N/R
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N/R
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N/R
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STANDARDS AND REGULATIONS:
ORGANIZATION
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STANDARD
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REFERENCE
Occupational Exposure Limit - RUSSIA
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short term exposure limit 5 mg/m3, JAN1993
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NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION
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STANDARD or SURVEY
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REFERENCE
National Occupational Hazard Survey 1974
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National Occupational Hazard Survey 1974: Hazard Code: M2556; | Number of Industries 83; Total Number of Facilities 12,848; Number of Occupations 25; Total Number of Employees Exposed 81,218
National Occupational Exposure Survey 1983
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National Occupational Exposure Survey 1983: Hazard Code: M2556 |
 ;Number of Industries 3; Total Number of Facilities 70; Number of Occupations 3; Total Number of Employees Exposed 621; Total Number of Female Employees Exposed 44 | ||||
STATUS IN FEDERAL AGENCIES:
ORGANIZATION
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REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
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Used as chemical intermediate, reaction media, solvent for paints, lacquers and resins
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EPA TSCA Section 8(d) unpublished health/safety studies
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On EPA IRIS database
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EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
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REFERENCES:
CODEN
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REFERENCE
AJOPAA
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American Journal of Ophthalmology. (Ophthalmic Pub. Co., 435 N. Michigan Ave., Suite 1415,
Chicago, IL 60611) Series 3: V.1- 1918-
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AMIHBC
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AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54.
For publisher information, see AEHLAU.
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GISAAA
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Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga,
113095 Moscow, USSR) V.1- 1936-
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VCVGK*
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"Vrednie chemichescie veshestva, galogen I kislorod sodergashie organicheskie soedinenia".
(Hazardous substances. Galogen and oxygen containing substances), Bandman A.L. et al., Chimia,
1994.
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