The Registry of Toxic Effects of Chemical Substances

Ethanol, 2 - (2 - (2 - butoxyethoxy) ethoxy) -

RTECS #: KJ9450000

CAS #: 143-22-6

UPDATE: October 1997 MW: 206.32 MF: C10H22O4


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. SKIN AND EYE IRRITATION DATA:
  3. ACUTE TOXICITY DATA:
  4. NIOSH DOCUMENTATION AND SURVEILLANCE:
  5. STATUS IN FEDERAL AGENCIES:
  6. REFERENCES:

SYNONYMS:

  1. 2 - (2 - (2 - Butoxyethoxy) ethoxy) ethanol
  2. Butoxytriethylene glycol
  3. Butoxytriglycol
  4. Poly - Solv TB
  1. Triethylene glycol n - butyl ether
  2. Triethylene glycol monobutyl ether
  3. Triglycol monobutyl ether
  4. 3,6,9 - Trioxa - 1 - tridecanol


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
eye
rabbit 		50 mg severe UCDS** 4/26/1965
eye
rabbit 		20 mg/24 hour moderate 85JCAE -,641,1986
skin
rabbit 		10 mg/24 hour open irritation test mild AIHAAP 23,95,1962
skin
rabbit 		500 mg/24 hour mild 85JCAE -,641,1986


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
oral
rat 		lethal dose (50 percent kill): 5,300 mg/kg Peripheral Nerve and Sensation: Flaccid paralysis without anesthesia (usually neuromuscular blockage)

Behavioral: Altered sleep time (including change in righting reflex) 		TSCAT* OTS 206801
skin
rabbit 		lethal dose (50 percent kill): 3,540 µL/kg Skin: After topical application: Primary irritation AIHAAP 23,95,1962


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: M0984;
Number of Industries 14;
Total Number of Facilities 1,954;
Number of Occupations 28;
Total Number of Employees Exposed 17,644
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: M0984;
Number of Industries 27;
Total Number of Facilities 3,319;
Number of Occupations 20;
Total Number of Employees Exposed 25,310;
Total Number of Female Employees Exposed 50


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used as chemical intermediate, reaction media, solvent for paints, lacquers and resins
EPA TSCA Section 8(d) unpublished health/safety studies
On EPA IRIS database
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986
AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958-
TSCAT* Office of Toxic Substances Report. (U.S. Environmental Protection Agency, Office of Toxic Substances, 401 M St., SW, Washington, DC 20460)
UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817)

Used as chemical intermediate, reaction media, solvent for paints, lacquers and resins

NIOSH PROFILE (GLYCOL ETHERS), SRI, 2/77

NIOSH PROFILE (GLYCOL ETHERS), SRC, 3/82

RTECS Compound Description:
   Primary Irritant

 Click Here for Additional Information about RTECS