The Registry of Toxic Effects of Chemical Substances

Ethanol, 2 - (2 - butoxyethoxy) - , acetate

RTECS #: KJ9275000

CAS #: 124-17-4

UPDATE: November 2004 MW: 204.30 MF: C10H20O4


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. SKIN AND EYE IRRITATION DATA:
  3. ACUTE TOXICITY DATA:
  4. OTHER MULTIPLE DOSE DATA:
  5. STANDARDS AND REGULATIONS:
  6. NIOSH DOCUMENTATION AND SURVEILLANCE:
  7. STATUS IN FEDERAL AGENCIES:
  8. REFERENCES:

SYNONYMS:

  1. Diethylene glycol butyl ether acetate
  2. Diethylene glycol, monobutyl ether, acetate
  3. Diglycol monobutyl ether acetate
  4. Ektasolve DB acetate
  5. Acetic acid 2 - (2 - butoxyethoxy) ethyl ester
  6. 2 - (2 - Butoxyethoxy) ethanol acetate
  1. 2 - (2 - Butoxyethoxy) ethyl acetate
  2. 2 - (2 - Butoxyethoxy) ethylester kyseliny octove (Czech)
  3. Butyl carbitol acetate
  4. Butylkarbitolacetat (Czech)
  5. Glycol ether DB aceatate


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
eye
rabbit 		500 mg moderate AJOPAA 29,1363,1946
skin
rabbit 		500 mg open irritation test mild UCDS** 12/29/1971


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
inhalation
rat 		lethal concentration (50 percent kill): 72,500 mg/m3/4 hour Eye: Other eye effects

Lung, Thorax, or Respiration: Dyspnea

Lung, Thorax, or Respiration: Other changes 		NTIS** OTS0571535
oral
chicken 		lethal dose (50 percent kill): 5 mL/kg N/R JPETAB 93,26,1948
oral
guinea pig 		lethal dose (50 percent kill): 2,340 mg/kg Behavioral: General anesthetic

Gastrointestinal: Other changes

Kidney, Ureter, and Bladder: Other changes 		JIHTAB 23,259,1941
oral
mouse 		lethal dose (50 percent kill): 6,600 µL/kg N/R JPETAB 93,26,1948
oral
rat 		lethal dose (50 percent kill): 6,500 mg/kg N/R 28ZEAL 5,32,1976
oral
rabbit 		lethal dose (50 percent kill): 2,260 mg/kg Behavioral: Sleep 38MKAJ 2C,4028,1982
skin
rabbit 		lethal dose (50 percent kill): 14,500 mg/kg N/R NPIRI* 1,27,1974


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
skin
rabbit 		lowest published toxic dose: 180 mL/kg/13 week- intermittent Behavioral: Muscle weakness

Nutritional and Gross Metabolic: Weight loss or decreased weight gain

Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field 		JPETAB 93,26,1948


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
Occupational Exposure Limit - THE NETHERLANDS MAC-TGG 130 mg/m3, 2003


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 83639;
Number of Industries 35;
Total Number of Facilities 1,483;
Number of Occupations 38;
Total Number of Employees Exposed 21,417
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 83639;
Number of Industries 42;
Total Number of Facilities 3,243;
Number of Occupations 46;
Total Number of Employees Exposed 45,220;
Total Number of Female Employees Exposed 10,562


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used as solvent in high bake enamels and as a coalescing aid in latex paints
EPA TSCA Section 8(d) unpublished health/safety studies
On EPA IRIS database
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE
28ZEAL "Pesticide Index," Frear, E.H., ed., State College, PA, College Science Pub., 1969
38MKAJ "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2nd rev. ed. in 1985.
AJOPAA American Journal of Ophthalmology. (Ophthalmic Pub. Co., 435 N. Michigan Ave., Suite 1415, Chicago, IL 60611) Series 3: V.1- 1918-
JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU.
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
NPIRI* Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. (National Assoc. of Printing Ink Research Institute, Francis McDonald Sinclair Memorial Laboratory, Lehigh Univ., Bethlehem, PA 18015)
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817)

Used as solvent in high bake enamels and as a coalescing aid in latex paints

RTECS Compound Description:
   Agricultural Chemical
   Primary Irritant

 Click Here for Additional Information about RTECS