The Registry of Toxic Effects of Chemical Substances

Ethanethiol

RTECS #: KI9625000

CAS #: 75-08-1

UPDATE: November 2004 MW: 62.14 MF: C2H6S


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. SKIN AND EYE IRRITATION DATA:
  3. ACUTE TOXICITY DATA:
  4. REVIEWS:
  5. STANDARDS AND REGULATIONS:
  6. NIOSH DOCUMENTATION AND SURVEILLANCE:
  7. STATUS IN FEDERAL AGENCIES:
  8. REFERENCES:

SYNONYMS:

  1. Aethanethiol (German)
  2. Aethylmercaptan (German)
  3. Etantiolo (Italian)
  4. Ethaanthiol (Dutch)
  5. Ethanethiol (OSHA)
  6. Ethyl hydrosulfide
  7. Ethyl mercaptan
  8. Ethyl mercaptan (ACGIH:OSHA)
  1. Ethyl sulfhydrate
  2. Ethyl thioalcohol
  3. Ethylmercaptaan (Dutch)
  4. Ethylmerkaptan (Czech)
  5. Etilmercaptano (Italian)
  6. LPG ethyl mercaptan 1010
  7. Thioethanol
  8. Thioethyl alcohol


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
eye
rabbit 		84 mg N/R AIHAAP 19,171,1958
eye
rabbit 		100 mg/24 hour moderate 85JCAE -,982,1986
skin
rabbit 		500 mg/24 hour mild 85JCAE -,982,1986


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
inhalation
mouse 		lethal concentration (50 percent kill): 2,770 ppm/4 hour Behavioral: Excitement

Behavioral: Change in motor activity (specific assay)

Lung, Thorax, or Respiration: Cyanosis 		AIHAAP 19,171,1958
inhalation
rat 		lethal concentration (50 percent kill): 4,420 ppm/4 hour Peripheral Nerve and Sensation: Spastic paralysis with/without sensory change

Behavioral: Excitement

Lung, Thorax, or Respiration: Cyanosis 		AIHAAP 19,171,1958
intraperitoneal
rat 		lethal dose (50 percent kill): 226 mg/kg Behavioral: Muscle weakness

Behavioral: Ataxia

Lung, Thorax, or Respiration: Cyanosis 		AIHAAP 19,171,1958
oral
rat 		lethal dose (50 percent kill): 682 mg/kg Behavioral: Muscle weakness

Behavioral: Ataxia

Lung, Thorax, or Respiration: Cyanosis 		AIHAAP 19,171,1958


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 0.5 ppm DTLVS* TLV/BEI,2003


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
Mine Safety and Health Administration (MSHA) STANDARD - air time-weighted average 0.5 ppm (1 mg/m3) DTLWS* 3,18,1973
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) ceiling concentration 10 ppm (25 mg/m3) CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) 8 hour time-weighted average 0.5 ppm (1 mg/m3) CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) ceiling concentration 0.5 ppm (1 mg/m3) CFRGBR 29,1915.1000,1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors) ceiling concentration 10 ppm (25 mg/m3) CFRGBR 41,50-204.50,1994
Occupational Exposure Limit - AUSTRALIA time-weighted average 0.5 ppm (1 mg/m3), JAN1993
Occupational Exposure Limit - AUSTRIA MAK 0.5 ppm (1 mg/m3), JAN1999
Occupational Exposure Limit - BELGIUM time-weighted average 0.5 ppm (1.3 mg/m3), JAN1993
Occupational Exposure Limit - FINLAND short term exposure limit 0.5 ppm (1.3 mg/m3), JAN1999
Occupational Exposure Limit - FRANCE VME 0.5 ppm (1 mg/m3), JAN1999
Occupational Exposure Limit - GERMANY MAK 0.5 ppm (1 mg/m3), JAN1999
Occupational Exposure Limit - HUNGARY short term exposure limit 1 mg/m3, JAN1993
Occupational Exposure Limit - THE NETHERLANDS MAC-TGG 1 mg/m3, 2003
Occupational Exposure Limit - THE PHILIPPINES time-weighted average 10 ppm (25 mg/m3), JAN1993
Occupational Exposure Limit - POLAND MAC(time-weighted average) 1 mg/m3, MAC(short term exposure limit) 3 mg/m3, JAN1999
Occupational Exposure Limit - RUSSIA short term exposure limit 1 mg/m3, Skin, JAN1993
Occupational Exposure Limit - SWITZERLAND MAK- week 0.5 ppm (1.3 mg/m3), KZG- week 1 ppm (2.6 mg/m3), JAN1999
Occupational Exposure Limit - THAILAND time-weighted average 10 ppm (25 mg/m3), JAN1993
Occupational Exposure Limit - TURKEY time-weighted average 10 ppm (25 mg/m3), JAN1993
Occupational Exposure Limit - UNITED KINGDOM time-weighted average 0.5 ppm (1.3 mg/m3), short term exposure limit 2 ppm, SEP2000
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN, KOREA American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

time-weighted average 0.5 ppm
Occupational Exposure Limit IN NEW ZEALAND, SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
time-weighted average 0.5 ppm


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO ETHANETHIOL-air ceiling concentration 0.5 ppm NIOSH* DHHS #92-100,1992
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 32760;
Number of Industries 1;
Total Number of Facilities 19;
Number of Occupations 15;
Total Number of Employees Exposed 1,476
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 32760;
Number of Industries 2;
Total Number of Facilities 110;
Number of Occupations 7;
Total Number of Employees Exposed 1,793;
Total Number of Female Employees Exposed 14


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NIOSH Analytical Method, 1994: Mercaptans, 2542


REFERENCES:

CODEN
REFERENCE
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986
AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958-
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402)
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
DTLWS* "Documentation of the Threshold Limit Values for Substances in Workroom Air," Supplements. For publisher information, see 85INA8.
NIOSH* National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda.

NIOSH PROFILE (MERCAPTANS), SRC, 10/77

RTECS Compound Description:
   Primary Irritant

 Click Here for Additional Information about RTECS