The Registry of Toxic Effects of Chemical Substances

Ethane, 1,2 - dichloro - 1,1,2,2 - tetrafluoro -

RTECS #: KI1101000

CAS #: 76-14-2

UPDATE: November 2004 MW: 170.92 MF: C2Cl2F4


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. ACUTE TOXICITY DATA:
  3. REVIEWS:
  4. STANDARDS AND REGULATIONS:
  5. NIOSH DOCUMENTATION AND SURVEILLANCE:
  6. STATUS IN FEDERAL AGENCIES:
  7. REFERENCES:

SYNONYMS:

  1. 1,1,2,2 - Tetrafluoro - 1,2 - dichloroethane
  2. 1,2 - Dichloro - 1,1,2,2 - tetrafluoroethane
  3. Arcton 114
  4. Arcton 33
  5. Cryofluoran
  6. Cryofluorane
  7. Dichlorotetrafluoroethane
  8. Dichlorotetrafluoroethane (ACGIH:OSHA)
  9. Ethane, 1,2 - dichlorotetrafluoro -
  10. F 114
  11. FC 114
  12. Fluorane 114
  1. Fluorocarbon 114
  2. Freon 114
  3. Frigen 114
  4. Frigiderm
  5. Genetron 114
  6. Genetron 316
  7. Halocarbon 114
  8. Ledon 114
  9. Propellant 114
  10. R 114
  11. Ucon 114
  12. sym - Dichlorotetrafluoroethane


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
inhalation
dog 		lowest published toxic concentration: 1,444,000 mg/m3/8 hour Behavioral: Convulsions or effect on seizure threshold VCVGH* -,639,1990
inhalation
guinea pig 		lethal concentration : >20 pph/8 hour N/R JOCMA7 4,262,1962
inhalation
mouse 		lethal concentration (50 percent kill): 70 pph/30 minute N/R EJTXAZ 9,385,1976
inhalation
rat 		lethal concentration (50 percent kill): 72 pph/30 minute N/R EJTXAZ 9,385,1976
inhalation
rabbit 		lethal concentration (50 percent kill): 75 pph/30 minute N/R EJTXAZ 9,385,1976
oral
rat 		lethal dose : >2,250 mg/kg N/R NTIS** OTS0520424


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 1000 ppm DTLVS* TLV/BEI,2003
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value Not Classifiable as a Human Carcinogen DTLVS* TLV/BEI,2003


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) 8 hour time-weighted average 1000 ppm (7000 mg/m3) CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) 8 hour time-weighted average 1000 ppm (7000 mg/m3) CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) 8 hour time-weighted average 1000 ppm (7000 mg/m3) CFRGBR 29,1915.1000,1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors) 8 hour time-weighted average 1000 ppm (7000 mg/m3) CFRGBR 41,50-204.50,1994
Occupational Exposure Limit - AUSTRALIA time-weighted average 1000 ppm (7000 mg/m3), JAN1993
Occupational Exposure Limit - AUSTRIA MAK 1000 ppm (7000 mg/m3), JAN1999
Occupational Exposure Limit - BELGIUM time-weighted average 1000 ppm (6990 mg/m3), JAN1993
Occupational Exposure Limit - DENMARK time-weighted average 500 ppm (3500 mg/m3), JAN1999
Occupational Exposure Limit - FINLAND time-weighted average 1000 ppm (7000 mg/m3), short term exposure limit 1250 ppm (8750 mg/m3), JAN1999
Occupational Exposure Limit - FRANCE VME 1000 ppm (7000 mg/m3), JAN1999
Occupational Exposure Limit - GERMANY MAK 1000 ppm (7000 mg/m3), JAN1999
Occupational Exposure Limit - HUNGARY time-weighted average 100 mg/m3, short term exposure limit 200 mg/m3, JAN1993
Occupational Exposure Limit - THE NETHERLANDS MAC-TGG 7130 mg/m3, 2003
Occupational Exposure Limit - NORWAY time-weighted average 500 ppm (3500 mg/m3), JAN1999
Occupational Exposure Limit - THE PHILIPPINES time-weighted average 1000 ppm (7000 mg/m3), JAN1993
Occupational Exposure Limit - POLAND MAC(time-weighted average) 5000 mg/m3, MAC(short term exposure limit) 8750 mg/m3, JAN1999
Occupational Exposure Limit - RUSSIA short term exposure limit 3000 mg/m3, JAN1993
Occupational Exposure Limit - SWITZERLAND MAK- week 1000 ppm (7000 mg/m3), JAN1999
Occupational Exposure Limit - TURKEY time-weighted average 1000 ppm (7000 mg/m3), JAN1993
Occupational Exposure Limit - UNITED KINGDOM time-weighted average 1000 ppm (7110 mg/m3), short term exposure limit 1250 ppm, SEP2000
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN, KOREA American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

Not Classifiable as a Human Carcinogen
Occupational Exposure Limit IN NEW ZEALAND, SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
Not Classifiable as a Human Carcinogen


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO DICHLOROTETRAFLUOROETHANE-air 10 hour time-weighted average 1000 ppm NIOSH* DHHS #92-100,1992
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: T1293;
Number of Industries 2;
Total Number of Facilities 38;
Number of Occupations 2;
Total Number of Employees Exposed 38
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: T1293;
Number of Industries 10;
Total Number of Facilities 1,140;
Number of Occupations 32;
Total Number of Employees Exposed 59,867;
Total Number of Female Employees Exposed 45,860


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NIOSH Analytical Method, 1994: 1,2-Dichlorotetrafluoroethane, 1018


REFERENCES:

CODEN
REFERENCE
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402)
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
EJTXAZ European Journal of Toxicology and Environmental Hygiene. (Paris, France) V.7-9, 1974-76. For publisher information, see TOERD9.
JOCMA7 Journal of Occupational Medicine. (Chicago, IL) V.1-9, 1957-67. For publisher information, see:JJOMDZ
NIOSH* National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda.
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
VCVGH* "Vrednie chemichescie veshestva, galogenproisvodnie uglevodorodov". (Hazardous substances: Galogenated hydrocarbons) Bandman A.L. et al., Chimia, 1990.

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