The Registry of Toxic Effects of Chemical Substances

Dodecylamine

RTECS #: JR6475000

CAS #: 124-22-1

UPDATE: October 1997 MW: 185.40 MF: C12H27N


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. SKIN AND EYE IRRITATION DATA:
  3. ACUTE TOXICITY DATA:
  4. NIOSH DOCUMENTATION AND SURVEILLANCE:
  5. STATUS IN FEDERAL AGENCIES:
  6. REFERENCES:

SYNONYMS:

  1. Alamine 4
  2. Amine BB
  3. 1 - Aminododecane
  4. Armeen 12D
  5. 1 - Dodecanamine (9CI)
  6. 1 - Dodecylamine
  7. Kemamine P690
  1. Laurinamine
  2. Laurylamine
  3. n - Laurylamine
  4. Monododecylamine
  5. Nissan amine BB
  6. n - Dodecylamine


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
eye
rabbit 		50 µg/24 hour severe 85JCAE -,438,1986
eye
rabbit 		2 mg severe AEPPAE 219,119,1953
skin
rabbit 		750 µg/24 hour severe 85JCAE -,438,1986


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
intraperitoneal
mouse 		lethal dose (50 percent kill): 50 mg/kg N/R NTIS** AD691-490
oral
mouse 		lethal dose (50 percent kill): 1,160 mg/kg Gastrointestinal: Other changes AEPPAE 219,119,1953
oral
rat 		lethal dose (50 percent kill): 1,020 mg/kg Gastrointestinal: Other changes AEPPAE 219,119,1953


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: A1342;
Number of Industries 1;
Total Number of Facilities 47;
Number of Occupations 2;
Total Number of Employees Exposed 377
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: A1342;
Number of Industries 2;
Total Number of Facilities 21;
Number of Occupations 15;
Total Number of Employees Exposed 2,134;
Total Number of Female Employees Exposed 306


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986
AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC.
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.

NIOSH PROFILE (AMINES, PRIMARY ALIPHATIC), SRI, 2/77

RTECS Compound Description:
   Drug
   Primary Irritant

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