RTECS:HD1400000 The Registry of Toxic Effects of Chemical Substances | CDC/NIOSH

The Registry of Toxic Effects of Chemical Substances

Decaborane (14)

RTECS #: HD1400000

CAS #: 17702-41-9

UPDATE: November 2004 MW: 122.24 MF: B₁₀H₁₄

NOTE:

TOXICITY DATA HAVE NOT BEEN EVALUATED. OMISSION OF A SUBSTANCE OR NOTATION DOES NOT IMPLY ANY RELIEF FROM REGULATORY RESPONSIBILITY.

TABLE OF CONTENTS:

SYNONYMS:

ACUTE TOXICITY DATA:

OTHER MULTIPLE DOSE DATA:

REVIEWS:

STANDARDS AND REGULATIONS:

NIOSH DOCUMENTATION AND SURVEILLANCE:

STATUS IN FEDERAL AGENCIES:

REFERENCES:

SYNONYMS:

Boron hydride (B10H14)

Decaborane

Decaborane (ACGIH:OSHA)

Decaborane (14) fumes

Tetradecahydrodecaborane

nido - Decaborane (14)

SKIN AND EYE IRRITATION DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

MUTATION DATA AND REFERENCES:
SYSTEM TEST ROUTE/
ORGANISM/
TISSUE DOSE REFERENCE
N/R N/R N/R N/R

REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

TUMORIGENIC DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
eye
rabbit lowest published toxic dose: 0.1 mg/kg/5 minute Eye: Conjunctiva irritation

Eye: Corneal damage VCVN1* -,201,1988
inhalation
mouse lethal concentration (50 percent kill): 12 ppm/4 hour Eye: Other eye effects

Behavioral: Somnolence (general depressed activity)

Behavioral: Ataxia NTIS** AD224-006
inhalation
mouse lethal concentration (50 percent kill): 30 mg/m³ N/R VCVN1* -,199,1988
inhalation
rat lethal concentration (50 percent kill): 46 ppm/4 hour Behavioral: Convulsions or effect on seizure threshold

Liver: Other changes

Kidney, Ureter, and Bladder: Other changes AMIHAB 17,362,1958
inhalation
rat lethal concentration (50 percent kill): 110 mg/m³/4 hour N/R VCVN1* -,199,1988
intraperitoneal
mouse lethal dose (50 percent kill): 33 mg/kg Behavioral: Convulsions or effect on seizure threshold

Behavioral: Ataxia

Lung, Thorax, or Respiration: Cyanosis AMIHAB 11,132,1955
intraperitoneal
mouse lethal dose (50 percent kill): 33 mg/kg Behavioral: Coma VCVN1* -,199,1988
intraperitoneal
rat lethal dose (50 percent kill): 23 mg/kg N/R AMIHBC 8,335,1953
intraperitoneal
rat lethal dose (50 percent kill): 23 mg/kg Behavioral: Coma VCVN1* -,199,1988
intraperitoneal
rabbit lethal dose (50 percent kill): 28 mg/kg N/R AMIHBC 8,335,1953
intraperitoneal
rabbit lethal dose (50 percent kill): 28 mg/kg Behavioral: Coma VCVN1* -,199,1988
oral
mouse lethal dose (50 percent kill): 41 mg/kg Eye: Corneal damage

Behavioral: Convulsions or effect on seizure threshold

Lung, Thorax, or Respiration: Cyanosis AMIHAB 11,132,1955
oral
rat lethal dose (50 percent kill): 64 mg/kg N/R MLSR** #8,1951
oral
rat lethal dose (50 percent kill): 64 mg/kg Behavioral: Coma VCVN1* -,199,1988
skin
cat lethal dose (50 percent kill): 126 mg/kg Behavioral: Convulsions or effect on seizure threshold

Liver: Fatty liver degeneration

Kidney, Ureter, and Bladder: Changes in tubules (including acute renal failure, acute tubular necrosis) STGNBT -,60,1999
skin
cat lethal dose (50 percent kill): 126 mg/kg/4 hour N/R VCVN1* -,201,1988
skin
guinea pig lethal dose (50 percent kill): 158 mg/kg Behavioral: Convulsions or effect on seizure threshold

Liver: Fatty liver degeneration

Kidney, Ureter, and Bladder: Changes in tubules (including acute renal failure, acute tubular necrosis) STGNBT -,60,1999
skin
guinea pig lethal dose (50 percent kill): 158 mg/kg/4 hour N/R VCVN1* -,201,1988
skin
mouse lethal dose (50 percent kill): 317 mg/kg Behavioral: Convulsions or effect on seizure threshold

Liver: Fatty liver degeneration

Kidney, Ureter, and Bladder: Changes in tubules (including acute renal failure, acute tubular necrosis) STGNBT -,60,1999
skin
mouse lethal dose (50 percent kill): 317 mg/kg/4 hour N/R VCVN1* -,201,1988
skin
rat lethal dose (50 percent kill): 740 mg/kg Peripheral Nerve and Sensation: Flaccid paralysis without anesthesia (usually neuromuscular blockage)

Behavioral: Convulsions or effect on seizure threshold

Lung, Thorax, or Respiration: Dyspnea AMIHAB 11,132,1955
skin
rat lethal dose (50 percent kill): 740 mg/kg/4 hour N/R VCVN1* -,201,1988
skin
rabbit lethal dose (50 percent kill): 71 mg/kg Behavioral: Altered sleep time (including change in righting reflex)

Behavioral: Ataxia

Lung, Thorax, or Respiration: Dyspnea AMIHAB 11,132,1955
skin
rabbit lethal dose (50 percent kill): 57 mg/kg/4 hour N/R VCVN1* -,201,1988

OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
inhalation
mouse lowest published toxic concentration: 22 mg/m³/5 hour/10 day- intermittent Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field VCVN1* -,199,1988
inhalation
rat lowest published toxic concentration: 22 mg/m³/5 hour/135 day- intermittent Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field VCVN1* -,199,1988
oral
rat lowest published toxic dose: 9,100 痢/kg/26 week- intermittent Brain and Coverings: Other degenerative changes

Behavioral: Somnolence (general depressed activity)

Blood: Pigmented or nucleated red blood cells STGNBT -,60,1999
oral
rabbit lowest published toxic dose: 1,050 痢/kg/21 day- intermittent Brain and Coverings: Other degenerative changes

Vascular: Other changes

Lung, Thorax, or Respiration: Other changes STGNBT -,60,1999

REVIEWS:
ORGANIZATION STANDARD
REFERENCE

American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 0.05 ppm (skin) DTLVS* TLV/BEI,2002
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 0.05 ppm (skin);short term exposure limit 0.15 ppm (skin) DTLVS* TLV/BEI,2003
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value short term exposure limit 0.15 ppm (skin) DTLVS* TLV/BEI,2002

STANDARDS AND REGULATIONS:
ORGANIZATION STANDARD
REFERENCE

Mine Safety and Health Administration (MSHA) STANDARD - air time-weighted average 0.05 ppm (0.3 mg/m³) (skin) DTLVS* 3,68,1971
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) 8 hour time-weighted average 0.05 ppm (0.3 mg/m³) (skin) CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) 8 hour time-weighted average 0.05 ppm (0.3 mg/m³) (skin) CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) 8 hour time-weighted average 0.05 ppm (0.3 mg/m³) (skin) CFRGBR 29,1915.1000,1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors) 8 hour time-weighted average 0.05 ppm (0.3 mg/m³) (skin) CFRGBR 41,50-204.50,1994
Occupational Exposure Limit - AUSTRALIA time-weighted average 005 ppm (0.3 mg/m³), short term exposure limit 0.15 ppm, Skin, JAN1993
Occupational Exposure Limit - AUSTRIA MAK 0.05 ppm (0.3 mg/m³), Skin, JAN1999
Occupational Exposure Limit - BELGIUM time-weighted average 0.05 ppm (0.25 mg/m³), short term exposure limit 0.15 ppm, Skin, JAN1993
Occupational Exposure Limit - DENMARK time-weighted average 0.05 ppm (0.3 mg/m³), Skin, JAN1999
Occupational Exposure Limit - FINLAND time-weighted average 0.05 ppm (0.25 mg/m³), short term exposure limit 0.15 ppm, Skin, JAN1999
Occupational Exposure Limit - FRANCE VME 0.05 ppm (0.3 mg/m³), Skin, JAN1999
Occupational Exposure Limit - GERMANY MAK 0.05 ppm (0.3 mg/m³), Skin, JAN1999
Occupational Exposure Limit - HUNGARY time-weighted average 0.3 mg/m³, short term exposure limit 0.6 mg/m³, Skin, JAN1993
Occupational Exposure Limit - THE NETHERLANDS MAC-TGG 0.3 mg/m³, 2003
Occupational Exposure Limit - NORWAY time-weighted average 0.05 ppm (0.3 mg/m³), JAN1999
Occupational Exposure Limit - THE PHILIPPINES time-weighted average 0.05 ppm (0.3 mg/m³), Skin, JAN1993
Occupational Exposure Limit - SWITZERLAND MAK- week 0.05 ppm (0.25 mg/m³), KZG- week 0.1 ppm, Skin, JAN1999
Occupational Exposure Limit - TURKEY time-weighted average 0.05 ppm (0.3 mg/m³), Skin, JAN1993
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN, KOREA American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

short term exposure limit 0.15 ppm (skin)
Occupational Exposure Limit IN NEW ZEALAND, SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
short term exposure limit 0.15 ppm (skin)

NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION STANDARD or SURVEY
REFERENCE

National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO DECABORANE-air 10 hour time-weighted average 0.05 ppm (Sk);
short term exposure limit 0.15 ppm (Sk) NIOSH* DHHS #95-121,1995

STATUS IN FEDERAL AGENCIES:
ORGANIZATION
REFERENCE

EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used as a catalyzer in polymers production
On EPA IRIS database

REFERENCES:
CODEN
REFERENCE

AMIHAB AMA Archives of Industrial Health. (Chicago, IL) V.11-21, 1955-60. For publisher information, see AEHLAU.
AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU.
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402)
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
MLSR** U.S. Army, Chemical Corps Medical Laboratories Special Reports. (Army Chemical Center, MD)
NIOSH* National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda.
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
STGNBT "Spravochnik po Toksikologii i Gigienicheskim Normativam (PDK) Potentsial'no Opasnykh Khimicheskikh Veshchestv" Kushneva, V.S., and R.B. Gorshkova, eds. 46, Zhivopisnaya St., 123182, Moscow, Russia, IzdAT 1999
VCVN1* "Vrednie chemichescie veshestva. Neorganicheskie soedinenia elementov I-IV groopp" (Hazardous substances. Inornanic substances containing I-IV group elements), Filov V.A., Chimia, 1988.

Used as a catalyzer in polymers production

ALT CAS #: 1304-02-5
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