UPDATE: December 1996 | MW: 338.48 | MF: C22H26O3 |
SYNONYMS:
|
|
|
SKIN AND EYE IRRITATION DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
N/R |
N/R
|
N/R
|
N/R
|
|
MUTATION DATA AND REFERENCES:
SYSTEM TEST
|
ROUTE/ | ORGANISM/ TISSUE
DOSE
|
REFERENCE
|
DNA inhibition
|
human
lymphocyte
|
130 µmol/L
|
DCTODJ 10,291,1987
|
DNA inhibition
|
mouse
leukocyte
|
235 µmol/L
|
DCTODJ 10,291,1987
|
micronucleus test
|
oral | rat
31 mg/kg
|
DCTODJ 10,291,1987
|
other mutation test systems
|
oral | rat
40 mg/kg
|
DCTODJ 10,291,1987
|
|
REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
N/R |
N/R
|
N/R
|
N/R
|
|
TUMORIGENIC DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
N/R |
N/R
|
N/R
|
N/R
|
|
ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
intraperitoneal | mouse
lethal dose (50 percent kill): 320 mg/kg
|
N/R
|
PCBPBS 4,456,1974
|
intravenous | rat
lethal dose (50 percent kill): 4,500 µg/kg
|
Behavioral: Tremor
|
PCBPBS 6,491,1976
|
oral | mouse
lethal dose (50 percent kill): 152 mg/kg
|
Behavioral: Tremor | Behavioral: Excitement Behavioral: Ataxia
EVHPAZ 14,15,1976
|
oral | rat
lethal dose (50 percent kill): 63 mg/kg
|
Behavioral: Tremor
|
PCBPBS 2,308,1972
|
|
OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
N/R |
N/R
|
N/R
|
N/R
|
|
REVIEWS:
ORGANIZATION
|
STANDARD
|
|
REFERENCE
N/R
|
N/R
|
N/R
|
|
STANDARDS AND REGULATIONS:
ORGANIZATION
|
STANDARD
|
|
REFERENCE
N/R
|
N/R
|
N/R
|
|
NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION
|
STANDARD or SURVEY
|
|
REFERENCE
N/R
|
N/R
|
N/R
|
|
STATUS IN FEDERAL AGENCIES:
ORGANIZATION
|
|
REFERENCE
N/R
|
|
REFERENCES:
CODEN
|
|
REFERENCE
DCTODJ
|
Drug and Chemical Toxicology. (Marcel Dekker, 270 Madison Ave., New York, NY 10016) V.1-
1977/78-
|
EVHPAZ
|
EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents,
Washington, DC 20402) No.1- 1972-
|
PCBPBS
|
Pesticide Biochemistry and Physiology. (Academic Press, Inc., 1 E. First St., Duluth, MN
55802) V.1- 1971-
|
|