The Registry of Toxic Effects of Chemical Substances

Cyclohexylamine, N,N - dimethyl -

RTECS #: GX1198000

CAS #: 98-94-2

UPDATE: July 2000 MW: 127.26 MF: C8H17N


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. ACUTE TOXICITY DATA:
  3. STANDARDS AND REGULATIONS:
  4. NIOSH DOCUMENTATION AND SURVEILLANCE:
  5. STATUS IN FEDERAL AGENCIES:
  6. REFERENCES:

SYNONYMS:

  1. Cyclohexanamine, N,N - dimethyl - (9CI)
  2. Cyclohexyldimethylamine
  3. N - Cyclohexyldimethylamine
  4. (Dimethylamino) cyclohexane
  1. N,N - Dimethylaminocyclohexane
  2. N,N - Dimethylcyclohexanamine
  3. N,N - Dimethylcyclohexylamine
  4. Polycat 8


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
inhalation
mouse 		lethal concentration (50 percent kill): 1,100 mg/m3/2 hour Behavioral: Muscle contraction or spasticity GTPZAB 28(5),54,1984
inhalation
rat 		lethal concentration (50 percent kill): 1,889 mg/m3/2 hour Behavioral: Muscle contraction or spasticity GTPZAB 28(5),54,1984
oral
guinea pig 		lethal dose (50 percent kill): 520 mg/kg N/R ZHYGAM 20,393,1974
oral
mouse 		lethal dose (50 percent kill): 320 mg/kg Behavioral: Muscle contraction or spasticity GTPZAB 28(5),54,1984
oral
rat 		lethal dose (50 percent kill): 348 mg/kg N/R ZHYGAM 20,393,1974
oral
rabbit 		lethal dose (50 percent kill): 620 mg/kg N/R ZHYGAM 20,393,1974
skin
rat 		lethal dose (50 percent kill): 370 mg/kg Behavioral: Tremor

Behavioral: Ataxia

Skin: After systemic exposure: Dermatitis, other 		NTIS** OTS0536456


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
Occupational Exposure Limit - RUSSIA short term exposure limit 1 mg/m3, Skin, JAN1993


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: M2994;
Number of Industries 1;
Total Number of Facilities 8;
Number of Occupations 2;
Total Number of Employees Exposed 24
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: M2994;
Number of Industries 11;
Total Number of Facilities 563;
Number of Occupations 16;
Total Number of Employees Exposed 6,130;
Total Number of Female Employees Exposed 253


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
ZHYGAM Zeitschrift fuer die Gesamte Hygiene und Ihre Grenzgebiete. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1955-

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