The Registry of Toxic Effects of Chemical Substances
Cyclohexanecarboxylic acid, 4 - (cyclopropylhydroxymethylene) - 3,5 - dioxo - , ethyl ester RTECS #: GU8473500
CAS #: 95266-40-3
The Registry of Toxic Effects of Chemical Substances
Cyclohexanecarboxylic acid, 4 - (cyclopropylhydroxymethylene) - 3,5 - dioxo - , ethyl ester |
| UPDATE: August 2003 | MW: 252.29 | MF: C13H16O5 |
SYNONYMS:
|
|
| |
SKIN AND EYE IRRITATION DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
N/R |
N/R
|
N/R
|
N/R
|
| |||
MUTATION DATA AND REFERENCES:
SYSTEM TEST
|
ROUTE/ | ORGANISM/ TISSUE
DOSE
|
REFERENCE
|
N/R
|
N/R
|
N/R
|
N/R
|
| |||
REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
N/R |
N/R
|
N/R
|
N/R
|
| |||
TUMORIGENIC DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
N/R |
N/R
|
N/R
|
N/R
|
| |||
ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
inhalation | rat
lethal concentration (50 percent kill): >5,300 mg/kg
|
N/R
|
NNGADV 22,351,1997
|
oral | mouse
lethal dose (50 percent kill): 5,409 mg/kg
|
N/R
|
NNGADV 22,351,1997
|
oral | rat
lethal dose (50 percent kill): 4,460 mg/kg
|
N/R
|
PEMNDP 9,351,1991
|
skin | rat
lethal dose (50 percent kill): >4 gm/kg
|
N/R
|
PEMNDP 9,351,1991
|
| |||
OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
oral | dog
lowest published toxic dose: 46,125 mg/kg/7 week- intermittent
|
Brain and Coverings: Changes in brain weight | Kidney, Ureter, and Bladder: Changes in tubules (including acute renal failure, acute tubular necrosis) Endocrine: Other changes
NTIS** OTS0543163
|
oral | dog
lowest published toxic dose: 34,125 mg/kg/13 week- intermittent
|
Endocrine: Other changes
|
NTIS** OTS0543199
|
oral | rat
lowest published toxic dose: 47 gm/kg/28 day- intermittent
|
Cardiac: Changes in heart weight | Kidney, Ureter, and Bladder: Changes in bladder weight Blood: Changes in serum composition (e.g. TP, bilirubin, cholesterol)
NTIS** OTS0543162
|
oral | rat
lowest published toxic dose: 27,300 mg/kg/13 week- intermittent
|
Kidney, Ureter, and Bladder: Changes in tubules (including acute renal failure, acute tubular necrosis) | Kidney, Ureter, and Bladder: Other changes
NTIS** OTS0543198
|
| |||
REVIEWS:
ORGANIZATION
|
STANDARD
|
|
REFERENCE
N/R
|
N/R
|
N/R
|
| ||
STANDARDS AND REGULATIONS:
ORGANIZATION
|
STANDARD
|
|
REFERENCE
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF
|
PESTICIDES: Active registration
|
RBREV* -,399,1998
|
| ||
NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION
|
STANDARD or SURVEY
|
|
REFERENCE
N/R
|
N/R
|
N/R
|
| ||
STATUS IN FEDERAL AGENCIES:
ORGANIZATION
|
|
REFERENCE
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
|
| ||
REFERENCES:
CODEN
|
|
REFERENCE
NNGADV
|
Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. (Nippon Noyaku
Gakkai, 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) V.1- 1976-
|
NTIS**
|
National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse
for Scientific & Technical Information.
|
PEMNDP
|
Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4
7QG, UK) V.1- 1968-
|
RBREV*
|
Status of Pesticides in Registration, Reregistration, and Special Review (Rainbow Report),
Special Review and Reregistration Division Office of Pesticide Programs U.S. Environmental
Protection Agency, 401 M. Street, S.W., Washington, D.C. 20460, Spring 1998
|
| |