The Registry of Toxic Effects of Chemical Substances

Copper (I) oxide

RTECS #: GL8050000

CAS #: 1317-39-1

UPDATE: August 2003 MW: 143.08 MF: Cu2O


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. REPRODUCTIVE EFFECTS DATA:
  3. ACUTE TOXICITY DATA:
  4. OTHER MULTIPLE DOSE DATA:
  5. REVIEWS:
  6. STANDARDS AND REGULATIONS:
  7. NIOSH DOCUMENTATION AND SURVEILLANCE:
  8. STATUS IN FEDERAL AGENCIES:
  9. REFERENCES:

SYNONYMS:

  1. C.I. 77402
  2. Brown copper oxide
  3. Caocobre
  4. Copox
  5. Copper nordox
  6. Copper oxide (8CI,9CI)
  7. Copper (1+) oxide
  8. Copper - sandoz
  9. Copper suboxide
  10. Cupper oxide (Russian)
  11. Cupramar
  12. Dicopper monoxide
  1. Fungimar
  2. Fungi - rhap Cu - 75
  3. Kupferoxydul (German)
  4. Kuprite
  5. Perenox
  6. Red copper oxide
  7. Cuprous oxide
  8. Nordox
  9. Oleocuivre
  10. Oleo nordox
  11. Oxyde cuivreux (French)
  12. Yellow cuprocide


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
inhalation
rat 		lowest published toxic concentration: 11 µg/m3/24 hour (14 week male) Reproductive: Effects on fertility: Male fertility index (e.g., # males impregnating females per # males exposed to fertile nonpregnant females) GISAAA 41(6),8,1976


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
intraperitoneal
mouse 		lethal dose (50 percent kill): 380 mg/kg N/R CUTOEX 1,39,1993
oral
rat 		lethal dose (50 percent kill): 470 mg/kg N/R VCVN1* -,67,1998


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
inhalation
rat 		lowest published toxic concentration: 1 mg/m3/24 hour/14 week- continuous Blood: Changes in serum composition (e.g. TP, bilirubin, cholesterol)

Blood: Other changes

Blood: Changes in erythrocyte (RBC) count 		GISAAA 41(6),8,1976


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
TOXICOLOGY REVIEW
85DHAX Cu,56,1977


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC 54,7740,1989
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF PESTICIDES: Supported RBREV* -,305,1998
Occupational Exposure Limit - ARAB Republic of Egypt time-weighted average 0.1 mg(Cu)/m3 (fume), JAN1993
Occupational Exposure Limit - AUSTRALIA time-weighted average 0.2 mg(Cu)/m3 (fume), JAN1993
Occupational Exposure Limit - AUSTRALIA time-weighted average 1 mg(Cu)/m3 (dust), JAN1993
Occupational Exposure Limit - BELGIUM time-weighted average 0.2 mg(Cu)/m3 (fume), JAN1993
Occupational Exposure Limit - BELGIUM time-weighted average 1 mg(Cu)/m3 (dust), JAN1993
Occupational Exposure Limit - FINLAND time-weighted average 0.2 mg(Cu)/m3 (fume), JAN1999
Occupational Exposure Limit - FINLAND time-weighted average 1 mg(Cu)/m3 (dust), JAN1999
Occupational Exposure Limit - FRANCE VME 0.2 mg(Cu)/m3 (fume), JAN1993
Occupational Exposure Limit - FRANCE VME 1 mg(Cu)/m3, short term exposure limit 2 mg(Cu)/m3 (dust), JAN1993
Occupational Exposure Limit - GERMANY MAK 0.1 mg(Cu)/m3 (fume), JAN1999
Occupational Exposure Limit - GERMANY MAK 1 mg(Cu)/m3 (dust), JAN1999
Occupational Exposure Limit - INDIA time-weighted average 0.2 mg(Cu)/m3 (fume), JAN1993
Occupational Exposure Limit - THE PHILIPPINES time-weighted average 1.0 mg(Cu)/m3 (fume), JAN1993
Occupational Exposure Limit - POLAND MAC(time-weighted average) 0.1 mg(Cu)/m3 (fume), JAN1993
Occupational Exposure Limit - RUSSIA short term exposure limit 0.5 ppm (1 mg(Cu)/m3) (dust), JAN1993
Occupational Exposure Limit - SWEDEN NGV 0.2 mg(Cu)/m3 (resp. dust), JAN1999
Occupational Exposure Limit - SWEDEN NGV 1 mg(Cu)/m3 (total dust), JAN1999
Occupational Exposure Limit - SWITZERLAND MAK- week 0.1 mg(Cu)/m3, short term exposure limit 0.2 mg(Cu)/m3 (fume), JAN1999
Occupational Exposure Limit - SWITZERLAND MAK- week 1 mg(Cu)/m3, short term exposure limit 1 mg(Cu)/m3, JAN1999
Occupational Exposure Limit - THAILAND time-weighted average 0.1 mg(Cu)/m3 (fume), JAN1993
Occupational Exposure Limit - THAILAND time-weighted average 1 mg(Cu)/m3, JAN1993
Occupational Exposure Limit - UNITED KINGDOM LTEL 0.2 mg(Cu)/m3 (fume), JAN1993
Occupational Exposure Limit - UNITED KINGDOM LTEL 1 mg(Cu)/m3, JAN1993


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 81679;
Number of Industries 7;
Total Number of Facilities 508;
Number of Occupations 14;
Total Number of Employees Exposed 9,387
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 81679;
Number of Industries 10;
Total Number of Facilities 1,612;
Number of Occupations 18;
Total Number of Employees Exposed 14,420;
Total Number of Female Employees Exposed 815


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used as catalyst and antioxidant in lubricants and in purification of helium
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE
85DHAX "Medical and Biologic Effects of Environmental Pollutants Series," Washington, DC, National Academy of Sciences, 1972-77
CUTOEX Current Toxicology. (Nova Science Publishers, Inc., 6080 Jericho Turnpike, Suite 207, Commack, NY 11725) V.1 1993-
FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936-
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
RBREV* Status of Pesticides in Registration, Reregistration, and Special Review (Rainbow Report), Special Review and Reregistration Division Office of Pesticide Programs U.S. Environmental Protection Agency, 401 M. Street, S.W., Washington, D.C. 20460, Spring 1998
VCVN1* "Vrednie chemichescie veshestva. Neorganicheskie soedinenia elementov I-IV groopp" (Hazardous substances. Inornanic substances containing I-IV group elements), Filov V.A., Chimia, 1988.

Used as catalyst and antioxidant in lubricants and in purification of helium

NIOSH PROFILE (COPPER and COMPOUNDS), SRC, 3/82

RTECS Compound Description:
   Agricultural Chemical
   Reproductive Effector

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