The Registry of Toxic Effects of Chemical Substances
Coal dust |
UPDATE: May 2004 | MW: N/R | MF: N/R |
SYNONYMS:
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SKIN AND EYE IRRITATION DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
|
N/R |
N/R
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N/R
|
N/R
|
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MUTATION DATA AND REFERENCES:
SYSTEM TEST
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ROUTE/ | ORGANISM/ TISSUE
DOSE
|
REFERENCE
|
N/R
|
N/R
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N/R
|
N/R
|
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REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
N/R |
N/R
|
N/R
|
N/R
|
|
TUMORIGENIC DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
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inhalation | rat
lowest published toxic concentration: 6,600 µg/m3/6 hour/86 week- intermittent
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Tumorigenic: Equivocal tumorigenic agent by RTECS criteria | Blood: Lymphoma including Hodgkin's disease
AIHAAP 42,382,1981
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inhalation | rat
toxic concentration (other than lowest) : 14,900 µg/m3/6 hour/86 week- intermittent
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Tumorigenic: Equivocal tumorigenic agent by RTECS criteria | Endocrine: Adrenal cortex tumors Blood: Lymphoma including Hodgkin's disease
AIHAAP 42,382,1981
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ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
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intratracheal | rat
lowest published toxic dose: 9.26 mg/kg
|
Lung, Thorax, or Respiration: Other changes | Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Cytochrome oxidases (indlucing oxidative phosphrylation) Biochemical: Metabolism (intermediary): Effect on inflammation or mediation of inflammation
TOXID9 72,320,2003
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OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
|
N/R |
N/R
|
N/R
|
N/R
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REVIEWS:
ORGANIZATION
|
STANDARD
|
|
REFERENCE
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
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time-weighted average 2 mg/m3, respirable dust
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DTLVS* TLV/BEI,1999
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International Agency for Research on Cancer (IARC) Cancer Review
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Human Inadequate Evidence
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IMEMDT 68,337,1997
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International Agency for Research on Cancer (IARC) Cancer Review
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Animal Inadequate Evidence
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IMEMDT 68,337,1997
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International Agency for Research on Cancer (IARC) Cancer Review
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Group 3
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IMEMDT 68,337,1997
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STANDARDS AND REGULATIONS:
ORGANIZATION
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STANDARD
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REFERENCE
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry)
|
8 hour time-weighted average 2.4 mg/m3/%SiO2+2 (resp frct <5% SiO2)
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CFRGBR 29,1910.1000,1994
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Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry)
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8 hour time-weighted average 10 mg/m3/%SiO2+2 (>5% SiO2)
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CFRGBR 29,1910.1000,1994
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Occupational Exposure Limit - UNITED KINGDOM
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LTEL 2 mg/m3 (respirable), JAN1993
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Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN, KOREA
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American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value; | time-weighted average 2 mg/m3, respirable dust
Occupational Exposure Limit IN NEW ZEALAND, SINGAPORE, VIETNAM
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American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value |
time-weighted average 2 mg/m3, respirable dust |
NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION
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STANDARD or SURVEY
|
|
REFERENCE
N/R
|
N/R
|
N/R
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STATUS IN FEDERAL AGENCIES:
ORGANIZATION
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REFERENCE
N/R
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REFERENCES:
CODEN
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REFERENCE
AIHAAP
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American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH
44311) V.19- 1958-
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CFRGBR
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Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents,
Washington, DC 20402)
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DTLVS*
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The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by
American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
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IMEMDT
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IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications
Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972-
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TOXID9
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Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1-
1981-
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