The Registry of Toxic Effects of Chemical Substances
Chromium (III) nitrate, nonahydrate (1:3:9) |
UPDATE: May 2004 | MW: 400.21 | MF: N3O9•Cr•9H2O |
SYNONYMS:
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SKIN AND EYE IRRITATION DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
N/R |
N/R
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N/R
|
N/R
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MUTATION DATA AND REFERENCES:
SYSTEM TEST
|
ROUTE/ | ORGANISM/ TISSUE
DOSE
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REFERENCE
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cytogenetic analysis
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hamster
ovary
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50 mg/L
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CRNGDP 3,1331,1982
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DNA inhibition
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human
fibroblast
|
1 mmol/L
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NASGEJ 3,237,1985
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DNA repair
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Escherichia coli
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62 µg/well
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MUREAV 133,161,1984
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mutation in microorganisms
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Salmonella typhimurium
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13,937 µg/plate (+enzymatic activation step)
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CRNGDP 3,1331,1982
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sister chromatid exchange
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hamster
ovary
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50 mg/L
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CRNGDP 3,1331,1982
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REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
N/R |
N/R
|
N/R
|
N/R
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TUMORIGENIC DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
N/R |
N/R
|
N/R
|
N/R
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ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
oral | rat
lethal dose (50 percent kill): 3,250 mg/kg
|
N/R
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AIHAAP 30,470,1969
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OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
|
inhalation | rabbit
lowest published toxic dose: 600 µg/m3/6 hour/17 week- intermittent
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Lung, Thorax, or Respiration: Other changes
|
ENVRAL 44,279,1987
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intraperitoneal | rat
lowest published toxic dose: 431 mg/kg/2 week- intermittent
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Liver: Other changes | Kidney, Ureter, and Bladder: Other changes Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Multiple enzyme effects
INHEAO 23,89,1985
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REVIEWS:
ORGANIZATION
|
STANDARD
|
|
REFERENCE
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
|
time-weighted average 0.5 mg(Cr)/m3
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DTLVS* TLV/BEI,1999
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American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
|
Not classifiable as a human carcinogen
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DTLVS* TLV/BEI,1999
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STANDARDS AND REGULATIONS:
ORGANIZATION
|
STANDARD
|
|
REFERENCE
Mine Safety and Health Administration (MSHA) STANDARD - air
|
time-weighted average 1 mg(Cr)/m3
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DTLVS* 3,35,1971
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Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry)
|
8 hour time-weighted average 0.5 mg(Cr)/m3
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CFRGBR 29,1910.1000,1994
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Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction)
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8 hour time-weighted average 0.5 mg(Cr)/m3
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CFRGBR 29,1926.55,1994
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Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards)
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8 hour time-weighted average 0.5 mg(Cr)/m3
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CFRGBR 29,1915.1000,1993
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Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors)
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8 hour time-weighted average 0.5 mg(Cr)/m3
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CFRGBR 41,50-204.50,1994
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NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION
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STANDARD or SURVEY
|
|
REFERENCE
N/R
|
N/R
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N/R
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STATUS IN FEDERAL AGENCIES:
ORGANIZATION
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|
REFERENCE
N/R
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REFERENCES:
CODEN
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REFERENCE
AIHAAP
|
American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH
44311) V.19- 1958-
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CFRGBR
|
Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents,
Washington, DC 20402)
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CRNGDP
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Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford
OX8 1JJ, UK) V.1- 1980-
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DTLVS*
|
The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by
American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
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ENVRAL
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Environmental Research. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1-
1967-
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INHEAO
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Industrial Health. (National Institute of Industrial Health, 6-21-1 Nagao, Tama-ku, Kawasaki,
213 Japan) V.1- 1963-
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MUREAV
|
Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1-
1964-
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NASGEJ
|
NATO ASI Series, Series G: Ecological Sciences. (Springer-Verlag New York, Inc., Service
Center, 44 Hartz Way, Secaucus, NJ 07094) No.1- 1983-
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