The Registry of Toxic Effects of Chemical Substances
Chromic acid, strontium salt (1:1) |
UPDATE: May 2005 | MW: 203.62 | MF: CrO4•Sr |
SYNONYMS:
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SKIN AND EYE IRRITATION DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
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N/R |
N/R
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N/R
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N/R
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MUTATION DATA AND REFERENCES:
SYSTEM TEST
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ROUTE/ | ORGANISM/ TISSUE
DOSE
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REFERENCE
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mutation in microorganisms
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Salmonella typhimurium
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800 ng/plate (+enzymatic activation step)
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MUREAV 156,219,1985
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morphological transform
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hamster
embryo
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100 µg/L
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CRNGDP 12,1811,1991
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sister chromatid exchange
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hamster
ovary
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100 µg/L
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MUREAV 156,219,1985
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REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
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N/R |
N/R
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N/R
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N/R
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TUMORIGENIC DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
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implant | rat
lowest published toxic dose: 125 mg/kg
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Tumorigenic: Equivocal tumorigenic agent by RTECS criteria | Tumorigenic: Tumors at site of application
AIHAAP 20,274,1959
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intratracheal | rat
lowest published toxic dose: 40 mg/kg/34 week- intermittent
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Tumorigenic: Equivocal tumorigenic agent by RTECS criteria | Lung, Thorax, or Respiration: Tumors Tumorigenic: Tumors at site of application
AEHLAU 5,445,1962
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ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
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inhalation | rat
lowest published toxic concentration: 40 mg/m3
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Behavioral: Alteration of classical conditioning
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VCVN1* -,128,1988
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inhalation | rat
lowest published toxic concentration: 20 mg/m3
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Nutritional and Gross Metabolic: Other changes
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VCVN1* -,128,1988
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intratracheal | rat
lethal dose (50 percent kill): 16.6 mg/kg
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N/R
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VCVN1* -,128,1988
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oral | mammal (species unspecified)
lethal dose (50 percent kill): >1,500 mg/kg
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N/R
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GTPZAB 19(8),43,1975
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oral | rat
lethal dose (50 percent kill): 3,118 mg/kg
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N/R
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VCVN1* -,128,1988
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OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
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N/R |
N/R
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N/R
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N/R
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REVIEWS:
ORGANIZATION
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STANDARD
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REFERENCE
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
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time-weighted average 0.0005 mg/m3
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DTLVS* TLV/BEI,2003
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American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
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Suspected Human Carcinogen
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DTLVS* TLV/BEI,2003
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American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
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short term exposure limit 0.0005 mg(Cr)/m3
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DTLVS* TLV/BEI,1999
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International Agency for Research on Cancer (IARC) Cancer Review
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Animal Sufficient Evidence
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IMEMDT 23,205,1980
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International Agency for Research on Cancer (IARC) Cancer Review
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Animal Sufficient Evidence
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IMEMDT 49,49,1990
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International Agency for Research on Cancer (IARC) Cancer Review
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Human Sufficient Evidence
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IMEMDT 23,205,1980
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International Agency for Research on Cancer (IARC) Cancer Review
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Human Sufficient Evidence
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IMEMDT 49,49,1990
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International Agency for Research on Cancer (IARC) Cancer Review
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Group 1
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IMEMDT 49,49,1990
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STANDARDS AND REGULATIONS:
ORGANIZATION
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STANDARD
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REFERENCE
Mine Safety and Health Administration (MSHA) STANDARD - air
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time-weighted average 0.5 mg(Cr)/m3
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DTLVS* 3,35,1971
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Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry)
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ceiling concentration 0.1 mg(CrO3)/m3
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CFRGBR 29,1910.1000,1994
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Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction)
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ceiling concentration 0.1 mg(CrO3)/m3
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CFRGBR 29,1926.55,1994
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Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards)
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ceiling concentration 0.1 mg(CrO3)/m3
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CFRGBR 29,1915.1000,1993
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Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors)
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ceiling concentration 0.1 mg(CrO3)/m3
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CFRGBR 41,50-204.50,1994
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Occupational Exposure Limit - ARAB Republic of Egypt
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time-weighted average 0.5 mg/m3, JAN1993
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Occupational Exposure Limit - AUSTRALIA
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time-weighted average 0.5 mg/m3, JAN1993
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Occupational Exposure Limit - AUSTRIA
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Carcinogen, JAN1999
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Occupational Exposure Limit - BELGIUM
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time-weighted average 0.5 mg/m3, JAN1993
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Occupational Exposure Limit - DENMARK
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time-weighted average 0.001 mg(Cr)/m3, JAN1999
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Occupational Exposure Limit - FINLAND
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time-weighted average 0.5 mg/m3, JAN1993
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Occupational Exposure Limit - FINLAND
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Carcinogen, JAN1999
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Occupational Exposure Limit - FRANCE
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VME 0.05 mg(Cr)/m3, JAN1999
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Occupational Exposure Limit - FRANCE
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Skin, JAN1993
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Occupational Exposure Limit - GERMANY
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Carcinogen, JAN1999
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Occupational Exposure Limit - INDIA
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time-weighted average 0.5 mg/m3, JAN1993
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Occupational Exposure Limit - JAPAN
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Occupational Exposure Limit 0.01 mg(Cr)/m3, JAN1999
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Occupational Exposure Limit - NORWAY
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time-weighted average 0.02 mg(CrO3)/m3, JAN1999
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Occupational Exposure Limit - THE PHILIPPINES
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time-weighted average 0.5 mg/m3, JAN1993
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Occupational Exposure Limit - POLAND
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time-weighted average 0.5 mg/m3, JAN1999
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Occupational Exposure Limit - SWEDEN
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NGV 0.02 mg/m3, Carcinogen, JAN1999
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Occupational Exposure Limit - SWITZERLAND
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MAK- week 0.05 mg(Cr)/m3, JAN1999
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Occupational Exposure Limit - THAILAND
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time-weighted average 1 mg/m3, JAN1993
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Occupational Exposure Limit - UNITED KINGDOM
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time-weighted average 0.05 mg(Cr)/m3, Carcinogen, SEP2000
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Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN, KOREA
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American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value; | short term exposure limit 0.0005 mg(Cr)/m3
Occupational Exposure Limit IN NEW ZEALAND, SINGAPORE, VIETNAM
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American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value |
short term exposure limit 0.0005 mg(Cr)/m3 |
NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION
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STANDARD or SURVEY
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REFERENCE
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO CHROMIUM(VI)-air
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Carcinogen; | 10 hour time-weighted average 0.001 mg(Cr)/m3
NIOSH* DHHS #92-100,1992
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National Occupational Hazard Survey 1974
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National Occupational Hazard Survey 1974: Hazard Code: M2287; | Number of Industries 19; Total Number of Facilities 627; Number of Occupations 28; Total Number of Employees Exposed 10,145
National Occupational Exposure Survey 1983
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National Occupational Exposure Survey 1983: Hazard Code: M2287; |
Number of Industries 28; Total Number of Facilities 1,164; Number of Occupations 36; Total Number of Employees Exposed 38,744; Total Number of Female Employees Exposed 2,855 |
STATUS IN FEDERAL AGENCIES:
ORGANIZATION
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REFERENCE
EPA GENETOX PROGRAM 1988, Positive: Carcinogenicity-mouse/rat
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EPA TSCA Section 8(b) CHEMICAL INVENTORY
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Used as a corrosion inhibitor and in wash primers and aluminum flake coatings
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EPA TSCA Section 8(d) unpublished health/safety studies
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EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
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NIOSH CURRENT INTELLIGENCE BULLETIN 4, 1975/1976
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NTP 11th Report on Carcinogens,2004:Known to be human carcinogen
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REFERENCES:
CODEN
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REFERENCE
AEHLAU
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Archives of Environmental Health. (Heldref Pub., 4000 Albemarle St., NW, Washington, DC
20016) V.1- 1960-
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AIHAAP
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American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH
44311) V.19- 1958-
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CFRGBR
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Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents,
Washington, DC 20402)
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CRNGDP
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Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford
OX8 1JJ, UK) V.1- 1980-
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DTLVS*
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The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by
American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
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GTPZAB
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Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see
MTPEEI
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IMEMDT
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IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications
Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972-
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MUREAV
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Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1-
1964-
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NIOSH*
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National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and
Welfare, Reports and Memoranda.
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VCVN1*
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"Vrednie chemichescie veshestva. Neorganicheskie soedinenia elementov I-IV groopp" (Hazardous
substances. Inornanic substances containing I-IV group elements), Filov V.A., Chimia, 1988.
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