The Registry of Toxic Effects of Chemical Substances

Cellulose

RTECS #: FJ5691460

CAS #: 9004-34-6

UPDATE: November 2004 MW: N/R MF: N/R


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. ACUTE TOXICITY DATA:
  3. OTHER MULTIPLE DOSE DATA:
  4. REVIEWS:
  5. STANDARDS AND REGULATIONS:
  6. NIOSH DOCUMENTATION AND SURVEILLANCE:
  7. STATUS IN FEDERAL AGENCIES:
  8. REFERENCES:

SYNONYMS:

  1. Abicel
  2. beta - Amylose
  3. Arbocel
  4. Arbocel BC 200
  5. Arbocell B 600/30
  6. Avicel
  7. Avicel 101
  8. Avicel 102
  9. Avicel CL 611
  10. Avicel PH 101
  11. Avicel PH 105
  12. Cellulose (ACGIH:OSHA)
  13. alpha - Cellulose
  14. Cellulose 248
  15. Cellulose crystalline
  16. Cellex MX
  17. Celufi
  18. CEPO
  19. Cepo CFM
  20. CEPO S 20
  21. CEPO S 40
  22. Chromedia CC 31
  23. Chromedia CF 11
  24. Cupricellulose
  25. Elcema F 150
  26. Elcema G 250
  27. Elcema P 050
  1. Elcema P 100
  2. Fresenius D 6
  3. Heweten 10
  4. Hydroxycellulose
  5. Kingcot
  6. LA 01
  7. Microcrystalline cellulose
  8. MN - Cellulose
  9. Onozuka P 500
  10. Pyrocellulose
  11. Rayophane
  12. Rayweb Q
  13. Rexcel
  14. Sigmacell
  15. Solka - floc BW 20
  16. Solka - floc BW 200
  17. Solka - floc BW 2030
  18. Solka - fil
  19. Solka - floc
  20. Solka - floc BW
  21. Solka - floc BW 100
  22. Spartose OM - 22
  23. Sulfite cellulose
  24. Tomofan
  25. Tunicin
  26. Whatman CC - 31


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
inhalation
rat 		lethal concentration (50 percent kill): >5,800 mg/m3/4 hour N/R TOLED5 (Suppl),243,1992
intraperitoneal
rat 		lethal dose (50 percent kill): >31,600 mg/kg N/R FAONAU 50A,83,1972
oral
rat 		lethal dose (50 percent kill): >5 gm/kg N/R TOLED5 (Suppl),243,1992
oral
rat 		lowest published toxic dose: 120 gm/kg Gastrointestinal: Hypermotility, diarrhea

Gastrointestinal: Other changes 		EPASR* #86940001000,1994
skin
rabbit 		lethal dose (50 percent kill): >2 gm/kg N/R TOLED5 (Suppl),243,1992


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
oral
rat 		lowest published toxic dose: 420 gm/kg/4 week- continuous Gastrointestinal: Other changes

Nutritional and Gross Metabolic: Weight loss or decreased weight gain 		AJPHAP 188,550,1957


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 10 mg/m3 DTLVS* TLV/BEI,2003


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) 8 hour time-weighted average 15 mg/m3, total dust CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) 8 hour time-weighted average 5 mg/m3, respirable fraction CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) 8 hour time-weighted average 15 mg/m3, total dust CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) 8 hour time-weighted average 5 mg/m3, respirable fraction CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) 8 hour time-weighted average 15 mg/m3, total dust CFRGBR 29,1915.1000,1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) 8 hour time-weighted average 5 mg/m3, respirable fraction CFRGBR 29,1915.1000,1993
Occupational Exposure Limit - AUSTRALIA time-weighted average 10 mg/m3, JAN1993
Occupational Exposure Limit - BELGIUM time-weighted average 10 mg/m3, JAN1993
Occupational Exposure Limit - FRANCE VME 10 mg/m3, JAN1999
Occupational Exposure Limit - RUSSIA time-weighted average 2 mg/m3, short term exposure limit 4 mg/m3, Skin, JAN1993
Occupational Exposure Limit - SWITZERLAND MAK- week 6 mg/m3, JAN1999
Occupational Exposure Limit - UNITED KINGDOM time-weighted average 10 mg/m3, short term exposure limit 20 mg/m3, Total Dust, SEP2000
Occupational Exposure Limit - UNITED KINGDOM time-weighted average 4 mg/m3, Respirable Dust, SEO2000
Occupational Exposure Limit - THE NETHERLANDS MAC-TGG 2 mg/m3, 2003
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN, KOREA American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

time-weighted average 10 mg/m3
Occupational Exposure Limit IN NEW ZEALAND, SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
time-weighted average 10 mg/m3


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO CELLULOSE, respirable fraction-air 10 hour time-weighted average 5 mg/m3 NIOSH* DHHS #95-121,1995
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO CELLULOSE, total dust-air 10 hour time-weighted average 10 mg/m3 NIOSH* DHHS #95-121,1995


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used as binders, thickeners, disintegrates in drug and food industry
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE
AJPHAP American Journal of Physiology. (American Physiological Soc., 9650 Rockville Pike, Bethesda, MD 20814) V.1- 1898-
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402)
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
EPASR* United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW, Washington, DC 20460) History unknown.
FAONAU FAO Nutrition Meetings Report Series. (Rome, Italy) No.?-57, 1948-77. Discontinued.
NIOSH* National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda.
TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977-

Used as binders, thickeners, disintegrates in drug and food industry

ALT CAS #: 9006-02-4
ALT CAS #: 39394-43-9
ALT CAS #: 58968-67-5
ALT CAS #: 61991-21-7
ALT CAS #: 61991-22-8
ALT CAS #: 84503-75-3
ALT CAS #: 99331-82-5
 Click Here for Additional Information about RTECS