The Registry of Toxic Effects of Chemical Substances

Carbonyl fluoride

RTECS #: FG6125000

CAS #: 353-50-4

UPDATE: May 2004 MW: 66.01 MF: CF2O


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. ACUTE TOXICITY DATA:
  3. REVIEWS:
  4. STANDARDS AND REGULATIONS:
  5. NIOSH DOCUMENTATION AND SURVEILLANCE:
  6. STATUS IN FEDERAL AGENCIES:
  7. REFERENCES:

SYNONYMS:

  1. Carbon fluoride oxide
  2. Carbonic difluoride (9CI)
  3. Carbon difluoride oxide
  4. Carbon oxyfluoride
  5. Carbonyl difluoride
  6. Carbonyl fluoride (ACGIH)
  1. Difluoroformaldehyde
  2. Difluorooxomethane
  3. Fluophosgene
  4. Fluoroformyl fluoride
  5. Fluorophosgene
  6. RCRA waste number U033


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
inhalation
rat 		lethal concentration (50 percent kill): 360 ppm/1 hour Lung, Thorax, or Respiration: Consolidation

Lung, Thorax, or Respiration: Fibrosis (interstitial)

Liver: Fatty liver degeneration 		AIHAAP 29,41,1968


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 2 ppm DTLVS* TLV/BEI,2002
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 2 ppm;short term exposure limit 5 ppm DTLVS* TLV/BEI,2003
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value short term exposure limit 5 ppm DTLVS* TLV/BEI,2002


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
Occupational Exposure Limit - AUSTRALIA time-weighted average 2 ppm (5 mg/m3), short term exposure limit 5 ppm, JAN1993
Occupational Exposure Limit - AUSTRIA MAK 2.5 mg(F)/m3, JAN1999
Occupational Exposure Limit - DENMARK time-weighted average 2 99m (6 mg/m3), JAN1999
Occupational Exposure Limit - FINLAND short term exposure limit 2 ppm (5 mg/m3), JAN1999
Occupational Exposure Limit - FRANCE VME 2 ppm (5 mg/m3), JAN1999
Occupational Exposure Limit - NORWAY time-weighted average 2 ppm (5 mg/m3), JAN1999
Occupational Exposure Limit - POLAND MAC(time-weighted average) 1 mg(HF)/m3, MAC(short term exposure limit) 3 mg(HF)/m3, JAN1999
Occupational Exposure Limit - SWITZERLAND MAK- week 2 ppm (5 mg/m3), JAN1999
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN, KOREA American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

short term exposure limit 5 ppm
Occupational Exposure Limit IN NEW ZEALAND, SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
short term exposure limit 5 ppm


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO CARBONYL FLUORIDE-air 10 hour time-weighted average 2 ppm;
short term exposure limit 5 ppm 		NIOSH* DHHS #95-121,1995


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used for synthesizing fluoroalkanes, difluoroisocyanates and fluorinated alkyl isocyanates
EPA TSCA Section 8(d) unpublished health/safety studies
On EPA IRIS database
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE
AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958-
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
NIOSH* National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda.

Used for synthesizing fluoroalkanes, difluoroisocyanates and fluorinated alkyl isocyanates

NIOSH PROFILE (CARBONYL FLUORIDE), SRC, 4/81

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