The Registry of Toxic Effects of Chemical Substances

Carbamic acid, methyl - , 4 - dimethylamino - m - tolyl ester

RTECS #: FC0175000

CAS #: 2032-59-9

UPDATE: August 2003 MW: 208.29 MF: C11H16N2O2


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. MUTATION DATA:
  3. ACUTE TOXICITY DATA:
  4. OTHER MULTIPLE DOSE DATA:
  5. STANDARDS AND REGULATIONS:
  6. REFERENCES:

SYNONYMS:

  1. A 363
  2. Aminocarb
  3. Aminocarbe (French)
  4. BAY 44646
  5. Bayer 5080
  6. Bayer 44646
  7. Carbamic acid, methyl - , 4 - (dimethylamino) - 3 - methylphenyl ester
  8. m - Cresol, 4 - (dimethylamino) - , methylcarbamate (ester)
  9. 4 - Dimethylamine m - cresyl methylcarbamate
  10. 4 - Dimethylamino - 3 - cresyl methylcarbamate
  11. 4 - (Dimethylamino) - 3 - methylphenol methyl carbamate (ester)
  1. (4 - Dimethylamino - 3 - methyl - phenyl) N - methyl - carbamaat (Dutch)
  2. (4 - Dimethylamino - 3 - methyl - phenyl) N - methyl - carbamat (German)
  3. (4 - Dimethylamino - 3 - methyl - phenyl) N - methyl - carbamate
  4. 4 - (Dimethylamino) - m - tolyl methylcarbamate
  5. (4 - Dimetilamino - 3 - metil - fenil) - N - metil - carbammato (Italian)
  6. ENT 25,784
  7. Matacil
  8. Matacil 180D
  9. N - Methylcarbamate de 4 - dimethylamino 3 - methyl phenyle (French)
  10. Mitacil
  11. Phenol, 4 - (dimethylamino) - 3 - methyl - , methylcarbamate (ester) (9CI)


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
cytogenetic analysis hamster ovary 5 mmol/L ENMUDM 5,384,1983
mutation in microorganisms Salmonella typhimurium 5 mmol/L (-enzymatic activation step) ENMUDM 5,384,1983
sex chromosome loss and nondisjunction Aspergillus nidulans 1,500 µmol/L MUREAV 178,33,1987


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
intraperitoneal
mouse 		lethal dose (50 percent kill): 4,700 µg/kg N/R JAFCAU 15,479,1967
intraperitoneal
rat 		lethal dose (50 percent kill): 21 mg/kg N/R PEMNDP 8,21,1987
oral
wild bird 		lethal dose (50 percent kill): 50 mg/kg N/R TXAPA9 21,315,1972
oral
duck 		lethal dose (50 percent kill): 23 mg/kg N/R DOEAAH 35,25,1979
oral
guinea pig 		lowest published lethal dose: 50 mg/kg N/R JEENAI 60,733,1967
oral
mouse 		lowest published lethal dose: 94 mg/kg N/R AECTCV 14,111,1985
oral
rat 		lethal dose (50 percent kill): 30 mg/kg N/R TXAPA9 21,315,1972
subcutaneous
guinea pig 		lowest published lethal dose: 50 mg/kg N/R JEENAI 60,733,1967
subcutaneous
mouse 		lethal dose (50 percent kill): 6,900 µg/kg N/R TOIZAG 17,60,1970
skin
mouse 		lethal dose (50 percent kill): 31 mg/kg N/R JAFCAU 15,479,1967
skin
rat 		lethal dose (50 percent kill): 275 mg/kg N/R WRPCA2 9,119,1970
unreported route
rat 		lethal dose (50 percent kill): 50 mg/kg N/R 30ZDA9 -,191,1971


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
inhalation
rat 		lowest published toxic concentration: 44 mg/m3/2 hour/30 day- intermittent Lung, Thorax, or Respiration: Changes in lung weight

Blood: Changes in serum composition (e.g. TP, bilirubin, cholesterol)

Biochemical: Metabolism (intermediary): Lipids including transport 		TXAPA9 82,181,1986


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC 54,7740,1989
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF PESTICIDES: Cancelled RBREV* -,159,1998


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
N/R N/R N/R


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
N/R


REFERENCES:

CODEN
REFERENCE
30ZDA9 "Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag New York, Inc., 1971
AECTCV Archives of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 070944) V.1- 1973-
DOEAAH Down to Earth. (Dow Chemical USA, Agricultural Products Dept., Midland, MI 48640) V.1- 1945-
ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG.
FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936-
JAFCAU Journal of Agricultural and Food Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) V.1- 1953-
JEENAI Journal of Economic Entomology. (Entomological Soc. of America, 4603 Calvert Rd., College Park, MD 20740) V.1- 1908-
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964-
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968-
RBREV* Status of Pesticides in Registration, Reregistration, and Special Review (Rainbow Report), Special Review and Reregistration Division Office of Pesticide Programs U.S. Environmental Protection Agency, 401 M. Street, S.W., Washington, D.C. 20460, Spring 1998
TOIZAG Toho Igakkai Zasshi. Journal of Medical Society of Toho University. (Toho Daigaku Igakkai, 21-16, Omori-nishi, 5-chome, Ota-ku, Tokyo 143, Japan) V.1- 1954-
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959-
WRPCA2 World Review of Pest Control. (London, UK) V.1-10, 1962-71. Discontinued.

Used for control of forest insects

RTECS Compound Description:
   Agricultural Chemical
   Mutagen

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