The Registry of Toxic Effects of Chemical Substances

Carbamic acid, dipropylthio - , S - ethyl ester

RTECS #: FA4550000

CAS #: 759-94-4

UPDATE: August 2003 MW: 189.35 MF: C9H19NOS


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. MUTATION DATA:
  3. ACUTE TOXICITY DATA:
  4. STANDARDS AND REGULATIONS:
  5. NIOSH DOCUMENTATION AND SURVEILLANCE:
  6. STATUS IN FEDERAL AGENCIES:
  7. REFERENCES:

SYNONYMS:

  1. S - Aethyl - N,N - dipropylthiolcarbamat (German)
  2. Alirox
  3. Carbamothioic acid, dipropyl - , S - ethyl ester (9CI)
  4. Dipropylcarbamothioic acid S - ethyl ester
  5. N,N - Dipropylthiocarbamic acid S - ethyl ester
  6. Eptam
  7. Eptam 6E
  8. EPTC
  9. S - Ethyldipropylthiocarbamate
  10. S - Ethyl - N,N - dipropylthiocarbamate
  1. S - Ethyl N,N - di - n - propylthiocarbamate
  2. Ethyl di - n - propylthiolcarbamate
  3. Ethyl - N,N - dipropylthiolcarbamate
  4. Ethyl N,N - di - n - propylthiolcarbamate
  5. FDA 1541
  6. Genep EPTC
  7. Niptan
  8. R - 1608
  9. Stauffer R 1608
  10. Torbin


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
mutation in microorganisms Escherichia coli 5 mg/L (-enzymatic activation step) GNKAA5 22,2416,1986


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
inhalation
cat 		lowest published lethal concentration: 400 mg/m3/4 hour Eye: Lacrimation

Behavioral: Somnolence (general depressed activity)

Gastrointestinal: Changes in structure or function of salivary glands 		HYSAAV 36(1-3),196,1971
inhalation
human 		lowest published toxic concentration: 135 mg/m3/90 minute Behavioral: Headache

Behavioral: Withdrawal

Gastrointestinal: Nausea or vomiting 		HYSAAV 36(1-3),196,1971
inhalation
rat 		lowest published lethal concentration: 200 mg/m3/4 hour Eye: Lacrimation

Behavioral: Somnolence (general depressed activity)

Gastrointestinal: Changes in structure or function of salivary glands 		HYSAAV 36(1-3),196,1971
intraperitoneal
mouse 		lethal dose (50 percent kill): 58 mg/kg N/R JAFCAU 25,404,1977
intravenous
mouse 		lethal dose (50 percent kill): 320 mg/kg N/R CSLNX* NX#03907
oral
wild bird 		lethal dose (50 percent kill): 100 mg/kg N/R TXAPA9 21,315,1972
oral
cat 		lethal dose (50 percent kill): 112 mg/kg N/R HYSAAV 36(1-3),196,1971
oral
mouse 		lethal dose (50 percent kill): 750 mg/kg N/R HYSAAV 36(1-3),196,1971
oral
rat 		lethal dose (50 percent kill): 916 mg/kg N/R NTIS** PB82-913299
oral
rabbit 		lethal dose (50 percent kill): 2,640 mg/kg N/R 85JCAE -,1020,1986
skin
rat 		lethal dose (50 percent kill): 3,200 mg/kg N/R GISAAA 36(2),29,1971
skin
rabbit 		lethal dose (50 percent kill): 1,460 mg/kg N/R WRPCA2 9,119,1970
unreported route
mammal (species unspecified) 		lethal dose (50 percent kill): 1,660 mg/kg N/R GISAAA 45(5),29,1980
unreported route
rat 		lethal dose (50 percent kill): 1,660 mg/kg N/R EQSSDX 3,618,1975


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC 54,7740,1989
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF PESTICIDES: Supported RBREV* -,116,1998
Occupational Exposure Limit - RUSSIA short term exposure limit 2 mg/m3, JAN1993


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 84803;
Number of Industries 1;
Total Number of Facilities 18;
Number of Occupations 2;
Total Number of Employees Exposed 684


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA GENETOX PROGRAM 1988, Negative: N crassa-aneuploidy
EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used for control of annual grassy weeds, nutgrass, perennial weeds, etc.
On EPA IRIS database


REFERENCES:

CODEN
REFERENCE
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010)
EQSSDX Environmental Quality and Safety, Supplement. (Stuttgart, Fed. Rep. Ger.) V.1-5, 1975-76. Discontinued.
FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936-
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
GNKAA5 Genetika (Moscow). For English translation, see SOGEBZ. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) No.1- 1965-
HYSAAV Hygiene and Sanitation (USSR). English translation of GISAAA. (Springfield, VA) 1964-71. Discontinued.
JAFCAU Journal of Agricultural and Food Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) V.1- 1953-
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
RBREV* Status of Pesticides in Registration, Reregistration, and Special Review (Rainbow Report), Special Review and Reregistration Division Office of Pesticide Programs U.S. Environmental Protection Agency, 401 M. Street, S.W., Washington, D.C. 20460, Spring 1998
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959-
WRPCA2 World Review of Pest Control. (London, UK) V.1-10, 1962-71. Discontinued.

Used for control of annual grassy weeds, nutgrass, perennial weeds, etc.

RTECS Compound Description:
   Agricultural Chemical
   Mutagen
   Human Data

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