The Registry of Toxic Effects of Chemical Substances

Cadmium sulfide

RTECS #: EV3150000

CAS #: 1306-23-6

UPDATE: May 2005 MW: 144.46 MF: CdS


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. MUTATION DATA:
  3. TUMORIGENIC DATA:
  4. ACUTE TOXICITY DATA:
  5. REVIEWS:
  6. STANDARDS AND REGULATIONS:
  7. NIOSH DOCUMENTATION AND SURVEILLANCE:
  8. STATUS IN FEDERAL AGENCIES:
  9. REFERENCES:

SYNONYMS:

  1. Cadmium monosulfide
  2. Cadmium golden 366
  3. Cadmium lemon Yellow 527
  4. Cadmium Orange
  5. Cadmium primrose 819
  6. Cadmium sulphide
  7. Cadmium Yellow
  8. Cadmium Yellow 000
  9. Cadmium Yellow 892
  10. Cadmium Yellow Conc. Deep
  11. Cadmium Yellow Conc. Golden
  12. Cadmium Yellow Conc. Lemon
  13. Cadmium Yellow Conc. Primrose
  14. Cadmium Yellow 10G Conc
  1. Cadmium Yellow OZ Dark
  2. Cadmium Yellow Primrose 47 - 4100
  3. Cadmopur Golden Yellow N
  4. Cadmopur Yellow
  5. Capsebon
  6. C.P. Golden Yellow 55
  7. Ferro Lemon Yellow
  8. Ferro Orange Yellow
  9. Ferro Yellow
  10. Greenockite
  11. GSK
  12. NCI - C02711
  13. PC 108
  14. Primrose 1466


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
cytogenetic analysis human leukocyte 62 µg/L PJACAW 48,133,1972
DNA damage hamster ovary 10 mg/L CRNGDP 3,657,1982
morphological transform hamster embryo 1 mg/L CNREA8 42,2757,1982


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
intramuscular
rat 		lowest published toxic dose: 120 mg/kg Tumorigenic: Equivocal tumorigenic agent by RTECS criteria

Tumorigenic: Tumors at site of application 		BJCAAI 20,190,1966
subcutaneous
rat 		lowest published toxic dose: 90 mg/kg Tumorigenic: Carcinogenic by RTECS criteria

Tumorigenic: Tumors at site of application 		BJCAAI 20,190,1966
subcutaneous
rat 		toxic dose : 135 mg/kg Tumorigenic: Equivocal tumorigenic agent by RTECS criteria

Tumorigenic: Tumors at site of application 		PBPHAW 14,47,1978
subcutaneous
rat 		toxic dose : 250 mg/kg Tumorigenic: Equivocal tumorigenic agent by RTECS criteria

Blood: Lymphoma including Hodgkin's disease

Tumorigenic: Tumors at site of application 		NATUAS 198,1213,1963


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
inhalation
rat 		lethal concentration : >140 mg/m3/2 hour N/R NTIS** OTS0539392
oral
mouse 		lethal dose (50 percent kill): 1,166 mg/kg N/R 41HTAH -,14,1978
oral
rat 		lethal dose (50 percent kill): 7,080 mg/kg N/R 41HTAH -,14,1978


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 0.01 mg(Cd)/m3, inhalable dust DTLVS* TLV/BEI,1999
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 0.002 mg(Cd)/m3, respirable dust DTLVS* TLV/BEI,1999
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value Suspected human carcinogen DTLVS* TLV/BEI,1999
International Agency for Research on Cancer (IARC) Cancer Review Animal Sufficient Evidence IMEMDT 2,74,1973
International Agency for Research on Cancer (IARC) Cancer Review Animal Sufficient Evidence IMEMDT 11,39,1976
International Agency for Research on Cancer (IARC) Cancer Review Animal Sufficient Evidence IMEMDT 58,119,1993
International Agency for Research on Cancer (IARC) Cancer Review Human Sufficient Evidence IMEMDT 58,119,1993
International Agency for Research on Cancer (IARC) Cancer Review Group 1 IMEMDT 58,119,1993
TOXICOLOGY REVIEW
FCTXAV 9,105,1971


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
Mine Safety and Health Administration (MSHA) STANDARD - air time-weighted average 0.2 mg(Cd)/m3 DTLVS* 3,34,1971
Occupational Exposure Limit - ARAB Republic of Egypt time-weighted average 0.05 mg(Cd)/m3, JAN1993
Occupational Exposure Limit - AUSTRALIA time-weighted average 0.05 mg(Cd)/m3, JAN1993
Occupational Exposure Limit - AUSTRIA Carcinogen, JAN1999
Occupational Exposure Limit - BELGIUM time-weighted average 0.05 mg(Cd)/m3, JAN1993
Occupational Exposure Limit - DENMARK time-weighted average 0.01 mg(Cd)/m3, JAN1999
Occupational Exposure Limit - FINLAND time-weighted average 0.02 mg(Cd)/m3, Carcinogen, Jan1999
Occupational Exposure Limit - FRANCE VME 0.05 mg(Cd)/m3, JAN1999
Occupational Exposure Limit - GERMANY Carcinogen, JAN1999
Occupational Exposure Limit - THE NETHERLANDS MAC-TGG 0.005 mg(Cd)/m3, 2003
Occupational Exposure Limit - JAPAN Occupational Exposure Limit 0.05 mg(Cd)/m3, Group 1 Carcinogen, JAN1999
Occupational Exposure Limit - NORWAY time-weighted average 0.05 mg(Cd)/m3, JAN1999
Occupational Exposure Limit - THE PHILIPPINES time-weighted average 0.2 mg(Cd)/m3, JAN1993
Occupational Exposure Limit - POLAND MAC(time-weighted average) fume 0.02 mg(Cd)/m3, MAC(short term exposure limit) fume 0.05 mg(Cd)/m3, JAN1999
Occupational Exposure Limit - POLAND MAC(time-weighted average) dust 0.04 mg(Cd)/m3, MAC(short term exposure limit) dust 0.2 mg(Cd)/m3, JAN1999
Occupational Exposure Limit - RUSSIA time-weighted average 0.01 mg(Cd)/m3, short term exposure limit 0.05 mg(Cd)/m3, JAN1993
Occupational Exposure Limit - SWEDEN Carcinogen, JAN1999
Occupational Exposure Limit - SWITZERLAND MAK- week 0.05 mg(Cd)/m3, Carcinogen, JAN1999
Occupational Exposure Limit - THAILAND time-weighted average 0.2 mg(Cd)/m3, short term exposure limit 0.5 mg(Cd)/m3, JAN1993
Occupational Exposure Limit - TURKEY time-weighted average 0.2 mg(Cd)/m3, JAN1993
Occupational Exposure Limit - UNITED KINGDOM time-weighted average 0.03 mg(Cd)/m3, SEP2000
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN, KOREA American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

Suspected human carcinogen
Occupational Exposure Limit IN NEW ZEALAND, SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
Suspected human carcinogen


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO CADMIUM, dust and fume-air Carcinogen lowest feasible conc. NIOSH* DHHS #92-100,1992
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 83628;
Number of Industries 29;
Total Number of Facilities 1,041;
Number of Occupations 41;
Total Number of Employees Exposed 19,293
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 83628;
Number of Industries 32;
Total Number of Facilities 1,625;
Number of Occupations 38;
Total Number of Employees Exposed 42,562;
Total Number of Female Employees Exposed 16,685


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA GENETOX PROGRAM 1988, Positive: Carcinogenicity-mouse/rat
EPA GENETOX PROGRAM 1988, Positive: In vitro cytogenetics-human lymphocyte
EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used in pigments and as an active ingredient of shampoos
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NTP 11th Report on Carcinogens,2004:Known to be human carcinogen


REFERENCES:

CODEN
REFERENCE
41HTAH "Aktual'nye Problemy Gigieny Truda. Current Problems of Labor Hygiene," Tarasenko, N.Y., ed., Moscow, Pervyi Moskovskii Meditsinskii Inst., 1978
BJCAAI British Journal of Cancer. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants. RG21 2XS, UK) V.1- 1947-
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941-
CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980-
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7.
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972-
NATUAS Nature. (Nature Subscription Dept., POB 1018, Manasguan, NJ 08736) V.1- 1869-
NIOSH* National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda.
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
PBPHAW Progress in Biochemical Pharmacology. (S. Karger AG, Postfach CH-4009 Basel, Switzerland) V.1- 1965-
PJACAW Proceedings of the Japan Academy. (Tokyo, Japan) V.21-53, 1945-77. For publisher information, see PJABDW.

Used in pigments and as an active ingredient of shampoos

NIOSH PROFILE (HAIRDRESSING and BARBERS), SRC, 6/80

RTECS Compound Description:
   Tumorigen
   Mutagen

ALT CAS #: 106496-20-2
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