The Registry of Toxic Effects of Chemical Substances
Benzylamine, N,N - dimethyl - |
UPDATE: July 2000 | MW: 135.23 | MF: C9H13N |
SYNONYMS:
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SKIN AND EYE IRRITATION DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
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eye | rabbit
5 mg
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severe
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DCTODJ 8,43,1985
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skin | rabbit
500 mg/4 hour
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severe
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DCTODJ 8,43,1985
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MUTATION DATA AND REFERENCES:
SYSTEM TEST
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ROUTE/ | ORGANISM/ TISSUE
DOSE
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REFERENCE
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N/R
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N/R
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N/R
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N/R
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REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
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N/R |
N/R
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N/R
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N/R
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TUMORIGENIC DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
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N/R |
N/R
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N/R
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N/R
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ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
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inhalation | mouse
lowest published lethal concentration: 1,200 mg/m3/2 hour
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Behavioral: Somnolence (general depressed activity) | Behavioral: Ataxia Lung, Thorax, or Respiration: Dyspnea
TPKVAL 5,6,1963
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inhalation | rat
lowest published lethal concentration: 1,200 mg/m3/2 hour
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Behavioral: Somnolence (general depressed activity) | Behavioral: Ataxia Lung, Thorax, or Respiration: Dyspnea
TPKVAL 5,6,1963
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oral | rat
lethal dose (50 percent kill): 265 mg/kg
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N/R
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KorCJ# 22AUG1974
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skin | rabbit
lethal dose (50 percent kill): 1,660 mg/kg
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Behavioral: Tremor | Behavioral: Excitement
DCTODJ 8,43,1985
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OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
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inhalation | rat
lowest published toxic concentration: 30 mg/m3/4 hour/26 week- intermittent
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Brain and Coverings: Recordings from specific areas of CNS | Kidney, Ureter, and Bladder: Other changes in urine composition
TPKVAL 5,6,1963
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REVIEWS:
ORGANIZATION
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STANDARD
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REFERENCE
N/R
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N/R
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N/R
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STANDARDS AND REGULATIONS:
ORGANIZATION
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STANDARD
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REFERENCE
Occupational Exposure Limit - RUSSIA
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short term exposure limit 5 mg/m3, JAN1993
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NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION
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STANDARD or SURVEY
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REFERENCE
National Occupational Hazard Survey 1974
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National Occupational Hazard Survey 1974: Hazard Code: 83034; | Number of Industries 5; Total Number of Facilities 142; Number of Occupations 34; Total Number of Employees Exposed 23,940
National Occupational Exposure Survey 1983
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National Occupational Exposure Survey 1983: Hazard Code: 83034; |
Number of Industries 8; Total Number of Facilities 110; Number of Occupations 8; Total Number of Employees Exposed 2,150; Total Number of Female Employees Exposed 249 |
STATUS IN FEDERAL AGENCIES:
ORGANIZATION
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REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
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Used as catalyst for EPOXY and POLYURETHANE resin systems
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EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
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REFERENCES:
CODEN
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REFERENCE
DCTODJ
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Drug and Chemical Toxicology. (Marcel Dekker, 270 Madison Ave., New York, NY 10016) V.1-
1977/78-
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KorCJ#
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Personal Communication from C.J. Korpics, Sherwin-Williams Chemicals, 1310 Expressway Drive,
Toledo, OH 43608, Aug. 22, 1974
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TPKVAL
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Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial
Chemical Substances. For English translation, see TNICS*. (Izdatel'stvo Meditsina, Moscow,
USSR) No.1- 1961-
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