The Registry of Toxic Effects of Chemical Substances

Benzylamine, N,N - dimethyl -

RTECS #: DP4500000

CAS #: 103-83-3


UPDATE: July 2000 MW: 135.23 MF: C9H13N


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. SKIN AND EYE IRRITATION DATA:
  3. ACUTE TOXICITY DATA:
  4. OTHER MULTIPLE DOSE DATA:
  5. STANDARDS AND REGULATIONS:
  6. NIOSH DOCUMENTATION AND SURVEILLANCE:
  7. STATUS IN FEDERAL AGENCIES:
  8. REFERENCES:

SYNONYMS:

  1. Araldite accelerator 062
  2. BDMA
  3. Benzenemethanamine, N,N - dimethyl - (9CI)
  4. Benzyl - N,N - dimethylamine
  5. N - Benzyldimethylamine
  1. N - (Phenylmethyl) dimethylamine
  2. N,N - Dimethylbenzenemethanamine
  3. Dimethylbenzylamine
  4. N,N - Dimethylbenzylamine
  5. Sumine 2015


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
eye
rabbit
5 mg severe DCTODJ 8,43,1985
skin
rabbit
500 mg/4 hour severe DCTODJ 8,43,1985


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE
DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
inhalation
mouse
lowest published lethal concentration: 1,200 mg/m3/2 hour Behavioral: Somnolence (general depressed activity)

Behavioral: Ataxia

Lung, Thorax, or Respiration: Dyspnea
TPKVAL 5,6,1963
inhalation
rat
lowest published lethal concentration: 1,200 mg/m3/2 hour Behavioral: Somnolence (general depressed activity)

Behavioral: Ataxia

Lung, Thorax, or Respiration: Dyspnea
TPKVAL 5,6,1963
oral
rat
lethal dose (50 percent kill): 265 mg/kg N/R KorCJ# 22AUG1974
skin
rabbit
lethal dose (50 percent kill): 1,660 mg/kg Behavioral: Tremor

Behavioral: Excitement
DCTODJ 8,43,1985


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
inhalation
rat
lowest published toxic concentration: 30 mg/m3/4 hour/26 week- intermittent Brain and Coverings: Recordings from specific areas of CNS

Kidney, Ureter, and Bladder: Other changes in urine composition
TPKVAL 5,6,1963


REVIEWS:

ORGANIZATION STANDARD
REFERENCE

N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE

Occupational Exposure Limit - RUSSIA short term exposure limit 5 mg/m3, JAN1993


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE

National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 83034;
Number of Industries 5;
Total Number of Facilities 142;
Number of Occupations 34;
Total Number of Employees Exposed 23,940
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 83034;
Number of Industries 8;
Total Number of Facilities 110;
Number of Occupations 8;
Total Number of Employees Exposed 2,150;
Total Number of Female Employees Exposed 249


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE

EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used as catalyst for EPOXY and POLYURETHANE resin systems
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE

DCTODJ Drug and Chemical Toxicology. (Marcel Dekker, 270 Madison Ave., New York, NY 10016) V.1- 1977/78-
KorCJ# Personal Communication from C.J. Korpics, Sherwin-Williams Chemicals, 1310 Expressway Drive, Toledo, OH 43608, Aug. 22, 1974
TPKVAL Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. (Izdatel'stvo Meditsina, Moscow, USSR) No.1- 1961-

Used as catalyst for EPOXY and POLYURETHANE resin systems

RTECS Compound Description:
   Primary Irritant

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