The Registry of Toxic Effects of Chemical Substances

Benzoic acid, benzyl ester

RTECS #: DG4200000

CAS #: 120-51-4

UPDATE: August 2003 MW: 212.26 MF: C14H12O2


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. ACUTE TOXICITY DATA:
  3. OTHER MULTIPLE DOSE DATA:
  4. STANDARDS AND REGULATIONS:
  5. NIOSH DOCUMENTATION AND SURVEILLANCE:
  6. STATUS IN FEDERAL AGENCIES:
  7. REFERENCES:

SYNONYMS:

  1. Ascabin
  2. Ascabiol
  3. Benylate
  4. Benzyl alcohol benzoic ester
  5. Benzyl benzenecarboxylate
  6. Benzyl benzoate
  7. Benzylester kyseliny benzoove (Czech)
  8. Benzylets
  1. Benzyl phenylformate
  2. Benzoic acid, phenylmethyl ester
  3. Colebenz
  4. Novoscabin
  5. Peruscabin
  6. Scabanca
  7. Vanzoate
  8. Venzonate


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
intraperitoneal
mouse 		lethal dose (50 percent kill): >500 mg/kg N/R 14CYAT 2,1897,1963
oral
cat 		lethal dose (50 percent kill): 2,240 mg/kg Behavioral: Tremor

Behavioral: Muscle weakness

Gastrointestinal: Changes in structure or function of salivary glands 		JPETAB 84,358,1945
oral
dog 		lethal dose (50 percent kill): >22,440 mg/kg N/R JPETAB 84,358,1945
oral
guinea pig 		lethal dose (50 percent kill): 1 mL/kg N/R JPETAB 93,26,1948
oral
mouse 		lethal dose (50 percent kill): 1,400 µL/kg N/R JPETAB 93,26,1948
oral
rat 		lethal dose (50 percent kill): 1,700 µL/kg N/R JPETAB 93,26,1948
oral
rabbit 		lethal dose (50 percent kill): 1,680 mg/kg N/R FCTXAV 11,1015,1973
skin
rat 		lethal dose (50 percent kill): 4 mL/kg N/R JPETAB 93,26,1948
skin
rabbit 		lethal dose (50 percent kill): 4 gm/kg N/R FCTXAV 11,1015,1973


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
skin
rabbit 		lowest published toxic dose: 180 mL/kg/13 week- intermittent Behavioral: Muscle weakness

Nutritional and Gross Metabolic: Weight loss or decreased weight gain

Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field 		JPETAB 93,26,1948


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC 54,7740,1989
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF PESTICIDES: Supported RBREV* -,297,1998


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 11590;
Number of Industries 7;
Total Number of Facilities 264;
Number of Occupations 38;
Total Number of Employees Exposed 11,292
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 11590;
Number of Industries 28;
Total Number of Facilities 5,972;
Number of Occupations 50;
Total Number of Employees Exposed 83,538;
Total Number of Female Employees Exposed 44,948


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY


REFERENCES:

CODEN
REFERENCE
14CYAT "Industrial Hygiene and Toxicology," 2nd ed., Patty, F.A., ed., New York, John Wiley & Sons, Inc., 1958-63
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7.
FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936-
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
RBREV* Status of Pesticides in Registration, Reregistration, and Special Review (Rainbow Report), Special Review and Reregistration Division Office of Pesticide Programs U.S. Environmental Protection Agency, 401 M. Street, S.W., Washington, D.C. 20460, Spring 1998

Used on animals as spot treatment in mange control; repellent for chiggers, mosquitoes, ticks

FDA-over the counter and proprietary drug

RTECS Compound Description:
   Agricultural Chemical
   Drug
   Natural Product

 Click Here for Additional Information about RTECS