The Registry of Toxic Effects of Chemical Substances

Benzin

RTECS #: DE3030000

CAS #: 8030-30-6

UPDATE: May 2004 MW: N/R MF: N/R


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. SKIN AND EYE IRRITATION DATA:
  3. TUMORIGENIC DATA:
  4. ACUTE TOXICITY DATA:
  5. OTHER MULTIPLE DOSE DATA:
  6. REVIEWS:
  7. STANDARDS AND REGULATIONS:
  8. NIOSH DOCUMENTATION AND SURVEILLANCE:
  9. STATUS IN FEDERAL AGENCIES:
  10. REFERENCES:

SYNONYMS:

  1. Amsco H - J
  2. Amsco H - SB
  3. Benzin B70
  4. Benzyna DO lakierow C (Polish)
  5. HI - Flash naphtha
  6. Hydrotreated naphtha
  7. Naphtha
  8. Naphtha (OSHA)
  9. Naphtha coal tar (OSHA)
  1. Naphtha, hydrotreated
  2. Petroleum benzin
  3. Petroleum distillates (naphtha) (OSHA)
  4. Petroleum naphtha
  5. Petroleum - derived naphtha
  6. Rubber solvent
  7. Rubber solvent (ACGIH)
  8. Super VMP


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
eye
rabbit 		100 µL mild JJATDK 9,59,1989
skin
rabbit 		500 µL moderate JJATDK 9,59,1989


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
skin
mouse 		lowest published toxic dose: 330 gm/kg/88 week- intermittent Tumorigenic: Carcinogenic by RTECS criteria

Skin and Appendages: Tumors 		FAATDF 9,297,1987


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
inhalation
human 		lowest published lethal concentration: 3 pph/5 minute N/R TABIA2 3,231,1933
inhalation
mouse 		lowest published lethal concentration: 10,600 mg/m3/6 hour N/R JJATDK 9,59,1989
inhalation
rat 		lowest published lethal concentration: 1,600 ppm/6 hour Behavioral: Somnolence (general depressed activity) CHINAG (17),1078,1939
intraperitoneal
mammal (species unspecified) 		lowest published lethal dose: 2,500 mg/kg Peripheral Nerve and Sensation: Flaccid paralysis without anesthesia (usually neuromuscular blockage)

Behavioral: Somnolence (general depressed activity)

Behavioral: Tremor 		AJHYA2 7,276,1927
intravenous
man 		lowest published lethal dose: 27 mg/kg Lung, Thorax, or Respiration: Dyspnea

Lung, Thorax, or Respiration: Respiratory stimulation

Lung, Thorax, or Respiration: Other changes 		CTOXAO 16,335,1980
oral
rat 		lethal dose (50 percent kill): >5 gm/kg N/R JJATDK 9,59,1989
oral
woman 		lowest published toxic dose: 20 mL/kg Lung, Thorax, or Respiration: Acute pulmonary edema

Lung, Thorax, or Respiration: Respiratory depression

Gastrointestinal: Nausea or vomiting 		JTCTDW 38,59,2000
oral
woman 		lowest published toxic dose: 20 mL/kg Behavioral: Somnolence (general depressed activity)

Lung, Thorax, or Respiration: Consolidation

Gastrointestinal: Nausea or vomiting 		JTCTDW 38,59,2000
skin
rabbit 		lethal dose (50 percent kill): >3 gm/kg Eye: Other eye effects

Behavioral: Food intake (animal) 		JJATDK 9,59,1989


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
inhalation
rat 		lowest published toxic concentration: 1,000 ppm/6 hour/12 day- intermittent Liver: Changes in liver weight

Kidney, Ureter, and Bladder: Other changes in urine composition

Kidney, Ureter, and Bladder: Changes in bladder weight 		FAATDF 9,120,1987
inhalation
rat 		lowest published toxic concentration: 1,000 ppm/6 hour/13 week- intermittent Kidney, Ureter, and Bladder: Other changes in urine composition

Kidney, Ureter, and Bladder: Changes in bladder weight

Endocrine: Changes in adrenal weight 		FAATDF 9,120,1987
inhalation
rabbit 		lowest published toxic concentration: 60 gm/m3/4 hour/26 week- intermittent Brain and Coverings: Other degenerative changes

Endocrine: Changes in pituitary weight

Endocrine: Changes in adrenal weight 		EDPKA2 29,399,1978
oral
rat 		lowest published toxic dose: 450 gm/kg/90 day- intermittent Liver: Changes in liver weight

Endocrine: Changes in adrenal weight

Nutritional and Gross Metabolic: Weight loss or decreased weight gain 		BCTKAG 21,187,1988


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 400 ppm DTLVS* TLV/BEI,2003


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
Mine Safety and Health Administration (MSHA) STANDARD - air time-weighted average 100 ppm (400 mg/m3) DTLVS* 3,176,1971
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) 8 hour time-weighted average 100 ppm (400 mg/m3) CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) 8 hour time-weighted average 100 ppm (400 mg/m3) CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) 8 hour time-weighted average 100 ppm (400 mg/m3) CFRGBR 29,1915.1000,1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors) 8 hour time-weighted average 100 ppm (400 mg/m3) CFRGBR 41,50-204.50,1994
Occupational Exposure Limit - AUSTRALIA time-weighted average 480 mg/m3, JAN1993
Occupational Exposure Limit - DENMARK time-weighted average 25 ppm (145 mg/m3), JAN1999
Occupational Exposure Limit - HUNGARY time-weighted average 300 mg/m3, short term exposure limit 800 mg/m3, JAN1993
Occupational Exposure Limit - THE PHILIPPINES time-weighted average 100 ppm (400 mg/m3), JAN1993
Occupational Exposure Limit - POLAND MAC(time-weighted average) 300 mg/m3, MAC(short term exposure limit) 900 mg/m3, JAN1999
Occupational Exposure Limit - RUSSIA short term exposure limit 100 mg/m3, JAN1993
Occupational Exposure Limit - SWITZERLAND MAK- week 300 mg/m3 (1100 mg/m3), JAN1999
Occupational Exposure Limit - TURKEY time-weighted average 100 ppm (400 mg/m3), JAN1993


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO NAPHTHA-air 10 hour time-weighted average 100 ppm NIOSH* DHHS #92-100,1992
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: M0628;
Number of Industries 225;
Total Number of Facilities 32,790;
Number of Occupations 134;
Total Number of Employees Exposed 327,083
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: M0628;
Number of Industries 232;
Total Number of Facilities 33,808;
Number of Occupations 133;
Total Number of Employees Exposed 471,013;
Total Number of Female Employees Exposed 57,366


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used as quick-drying paint solvent, manufacture of floor covering, resin solution, varnish
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NIOSH Analytical Method, 1994: Naphthas, 1550


REFERENCES:

CODEN
REFERENCE
AJHYA2 American Journal of Hygiene. (Baltimore, MD) V.1-80, 1921-64. For publisher information, see AJEPAS.
BCTKAG Bromatologia i Chemia Toksykologiczna. (Ars Polona, POB 1001, 00-068 Warsaw 1, Poland) V.4- 1971-
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402)
CHINAG Chemistry and Industry (London). (Royal Soc. of Chemistry, Distribution Centre, Blackhorse Rd., Letchworth, Herts SG6 1HN, UK) V.1- 1923-
CTOXAO Clinical Toxicology. (New York, NY) V.1-18, 1968-81. For publisher information, see JTCTDW.
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
EDPKA2 Endokrynologia Polska. (Ars Polona, POB 1001, 00-068 Warsaw, Poland) V.1- 1950-
FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1-40, 1981-97. For publisher information, see TOSCF2
JJATDK JAT, Journal of Applied Toxicology. (John Wiley & Sons Ltd., Baffins Lane, Chichester, W. Sussex PO19 1UD, UK) V.1- 1981-
JTCTDW Journal of Toxicology, Clinical Toxicology. (Marcel Dekker, 270 Madison Ave., New York, NY 10016) V.19- 1982-
NIOSH* National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda.
TABIA2 Tabulae Biologicae. (The Hague, Netherlands) V.1-22, 1925-63. Discontinued.

Used as quick-drying paint solvent, manufacture of floor covering, resin solution, varnish

NIOSH PROFILE (PAINT AND ALLIED PRODUCTS MANUFACTURING), FIRL, 4/78

NIOSH PROFILE (SPRAY PAINTING), FIRL, 4/78

NIOSH PROFILE (PAINT AND ALLIED PRODUCTS MANUFACTURING), SRI, 2/7

RTECS Compound Description:
   Agricultural Chemical
   Tumorigen
   Human Data
   Primary Irritant

ALT CAS #: 8030-31-7
ALT CAS #: 50813-73-5
ALT CAS #: 54847-97-1
ALT CAS #: 121448-83-7
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