The Registry of Toxic Effects of Chemical Substances

2 - Benzimidazolecarbamic acid, 1 - (butylcarbamoyl) - , methyl ester

RTECS #: DD6475000

CAS #: 17804-35-2

UPDATE: February 2005 MW: 290.36 MF: C14H18N4O3


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. SKIN AND EYE IRRITATION DATA:
  3. MUTATION DATA:
  4. REPRODUCTIVE EFFECTS DATA:
  5. ACUTE TOXICITY DATA:
  6. OTHER MULTIPLE DOSE DATA:
  7. REVIEWS:
  8. STANDARDS AND REGULATIONS:
  9. NIOSH DOCUMENTATION AND SURVEILLANCE:
  10. STATUS IN FEDERAL AGENCIES:
  11. REFERENCES:

SYNONYMS:

  1. 1 - (Butylcarbamoyl) - 2 - benzimidazol - methylcarbamat (German)
  2. 1 - (Butylcarbamoyl) - 2 - benzimidazolecarbamic acid, methyl ester
  3. 1 - (N - Butylcarbamoyl) - 2 - (methoxy - carboxamido) - benzimidazol (German)
  4. Agrocit
  5. BBC
  6. BC 6597
  7. Benlate
  8. Benlate 50
  9. Benlate 50 W
  10. Benomyl
  11. Benomyl (ACGIH:OSHA)
  12. Benomyl 50W
  13. Benomyl - Imex
  1. Carbamic acid, (1 - ( (butylamino) carbonyl) - 1H - benzimidazol - 2 - yl) - , methyl ester (9CI)
  2. Chinoin - fundazol
  3. D 1991
  4. Du Pont 1991
  5. Fundazol
  6. Fungicide D - 1991
  7. Fungochrom
  8. MBC
  9. NS 02
  10. NS 02 (fungicide)
  11. Tersan 1991
  12. Uzgen


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
skin
man 		0.1% mild LANCAO 2,1252,1980


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
cytogenetic analysis hamster lung 100 µmol/L MUREAV 26,177,1974
cytogenetic analysis human liver 100 µmol/L MUREAV 26,177,1974
cytogenetic analysis human HeLa cell 100 µmol/L MUREAV 26,177,1974
cytogenetic analysis human lymphocyte 10 mg/L CYGEDX 17(1),29,1983
cytogenetic analysis oral
mouse 		1 gm/kg MUREAV 300,15,1993
cytogenetic analysis intraperitoneal
rat 		1 gm/kg MUREAV 26,177,1974
DNA inhibition oral
mouse 		375 mg/kg FCTOD7 28,701,1990
DNA repair Salmonella typhimurium 250 µg/disc JPFCD2 21,319,1986
mutation in microorganisms Aspergillus nidulans 250 µg/L (-enzymatic activation step) MUREAV 91,115,1981
mutation in microorganisms Bacillus subtilis 5,000 ppm (-enzymatic activation step) MUREAV 53,209,1978
mutation in microorganisms Escherichia coli 125 µg/L (-enzymatic activation step) MUREAV 40,379,1976
mutation in microorganisms other microorganisms 5 mg/L (-enzymatic activation step) MUREAV 21,119,1973
mutation in microorganisms Salmonella typhimurium 125 µg/L (+enzymatic activation step) MUREAV 40,379,1976
mutation in microorganisms Saccharomyes cerevisiae 50 ppm (-enzymatic activation step) RSTUDV 6,161,1976
micronucleus test hamster ovary 34,400 nmol/L MUREAV 224,517,1989
micronucleus test human lymphocyte 10 mg/L MUREAV 388,27,1997
micronucleus test intraperitoneal
mouse 		500 mg/kg/24 hour NTIS** PB84-138973
micronucleus test oral
mouse 		2,500 mg/kg MUREAV 310,143,1994
micronucleus test mouse other cell types 10 mg/L JNCIAM 56,357,1976
micronucleus test oral
rat 		3,500 mg/kg/10 week- continuous EMMUEG 16,32,1990
micronucleus test rat liver 500 µg/L MUREAV 324,59,1994
gene conversion and mitotic recombination Aspergillus nidulans 250 ppb NATUAS 226,771,1970
mutation in mammalian somatic cells mouse lymphocyte 15 mg/L NTIS** PB84-138973
morphological transform hamster embryo 2 mg/L MUREAV 343,7,1995
other mutation test systems human lymphocyte 2 mg/L EMMUEG 16,32,1990
sister chromatid exchange hamster ovary 375 mg/L NTIS** PB84-138973
sister chromatid exchange human lymphocyte 250 µg/L EMMUEG 16,32,1990
sex chromosome loss and nondisjunction Aspergillus nidulans 200 µg/L EVHPAZ 31,81,1979
sex chromosome loss and nondisjunction hamster ovary 34,400 nmol/L MUREAV 224,517,1989
sex chromosome loss and nondisjunction human lymphocyte 1 mg/L MUREAV 121,139,1983
sex chromosome loss and nondisjunction oral
mouse 		1 gm/kg MUREAV 300,15,1993
sex chromosome loss and nondisjunction Saccharomyes cerevisiae 123 ppm ANYAA9 407,186,1983


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
oral
mouse 		lowest published toxic dose: 250 mg/kg (11 day pregnant) Reproductive: Effects on embryo or fetus: Fetal death JHEMA2 24,295,1980
oral
mouse 		lowest published toxic dose: 1,100 mg/kg (7-17 day pregnant) Reproductive: Effects on embryo or fetus: Fetotoxicity (except death, e.g., stunted fetus)

Reproductive: Specific developmental abnormalities: Central nervous system

Reproductive: Specific developmental abnormalities: Craniofacial (including nose and tongue) 		TXAPA9 62,44,1982
oral
mouse 		lowest published toxic dose: 1,100 mg/kg (7-17 day pregnant) Reproductive: Specific developmental abnormalities: Musculoskeletal system

Reproductive: Specific developmental abnormalities: Urogenital system 		TXAPA9 62,44,1982
oral
mouse 		lowest published toxic dose: 2,200 mg/kg (7-17 day pregnant) Reproductive: Effects on embryo or fetus: Fetal death

Reproductive: Specific developmental abnormalities: Body wall 		TXAPA9 62,44,1982
oral
mouse 		lowest published toxic dose: 500 mg/kg (13 day pregnant) Reproductive: Specific developmental abnormalities: Central nervous system

Reproductive: Specific developmental abnormalities: Musculoskeletal system 		JHEMA2 24,295,1980
oral
mouse 		lowest published toxic dose: 1 gm/kg (8-12 day pregnant) Reproductive: Effects on newborn: Live birth index (Litter size (e.g., # fetuses per litter; measured after birth)

Reproductive: Effects on newborn: Viability index (e.g., # alive at day 4 per # born alive)

Reproductive: Effects on newborn: Growth statistics (e.g., reduced weight gain) 		JTEHD6 10,541,1982
oral
rat 		lowest published toxic dose: 3,500 µg/kg (70 day male) Reproductive: Effects on fertility: Male fertility index (e.g., # males impregnating females per # males exposed to fertile nonpregnant females) TXCYAC 28,103,1983
oral
rat 		lowest published toxic dose: 936 mg/kg (7-21 day pregnant) Reproductive: Effects on fertility: Post- implantation mortality (e.g., dead and/or resorbed implants per total number of implants)

Reproductive: Effects on embryo or fetus: Fetotoxicity (except death, e.g., stunted fetus)

Reproductive: Specific developmental abnormalities: Eye, ear 		CEYRDM 10,601,1991
oral
rat 		lowest published toxic dose: 250 mg/kg (12 day pregnant) Reproductive: Effects on fertility: Post- implantation mortality (e.g., dead and/or resorbed implants per total number of implants)

Reproductive: Other developmental abnormalities 		BEXBAN 83,247,1977
oral
rat 		lowest published toxic dose: 1,250 mg/kg (5 day male) Reproductive: Paternal effects: Spermatogenesis (including genetic material, sperm morphology, motility, and count)

Reproductive: Paternal effects: Testes, epididymis, sperm duct 		JTEHD6 13,53,1984
oral
rat 		lowest published toxic dose: 625 mg/kg (7-17 day pregnant) Reproductive: Effects on embryo or fetus: Fetotoxicity (except death, e.g., stunted fetus)

Reproductive: Specific developmental abnormalities: Central nervous system 		TXAPA9 62,44,1982
oral
rat 		lowest published toxic dose: 156 mg/kg (7-16 day pregnant) Reproductive: Specific developmental abnormalities: Musculoskeletal system TXAPA9 62,44,1982
oral
rat 		lowest published toxic dose: 85 gm/kg (multigenerations) Reproductive: Effects on newborn: Weaning or lactation index (e.g., # alive at weaning per # alive at day 4) ATSUDG 4,459,1980
parenteral
rat 		lowest published toxic dose: 250 mg/kg (10 day pregnant) Reproductive: Effects on embryo or fetus: Fetal death

Reproductive: Specific developmental abnormalities: Central nervous system 		40YJAX -,127,1979
unreported route
rat 		lowest published toxic dose: 250 mg/kg (12 day pregnant) Reproductive: Effects on fertility: Post- implantation mortality (e.g., dead and/or resorbed implants per total number of implants)

Reproductive: Other developmental abnormalities 		GISAAA 41(12),32,1976


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
inhalation
rat 		lethal concentration (50 percent kill): >2 gm/m3/4 hour N/R PEMNDP 9,59,1991
oral
wild bird 		lethal dose (50 percent kill): 100 mg/kg N/R TXAPA9 21,315,1972
oral
rat 		lethal dose (50 percent kill): 10 gm/kg N/R JHEMA2 24,295,1980
oral
rat 		lowest published toxic dose: 400 mg/kg Reproductive: Paternal effects: Spermatogenesis (including genetic material, sperm morphology, motility, and count)

Reproductive: Paternal effects: Testes, epididymis, sperm duct

Related to Chronic Data: Changes in testicular weight 		REPTED 6,491,1992
skin
rat 		lethal dose (50 percent kill): >1 gm/kg N/R WRPCA2 9,119,1970
skin
rabbit 		lethal dose (50 percent kill): >10 gm/kg N/R PEMNDP 9,59,1991
unreported route
mammal (species unspecified) 		lethal dose (50 percent kill): 10 gm/kg N/R GISAAA 41(8),82,1976
unreported route
rat 		lethal dose (50 percent kill): 9,920 mg/kg N/R EQSSDX 3,618,1975


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
inhalation
rat 		lowest published toxic concentration: 200 mg/m3/6 hour/14 week- intermittent Olfaction: Other olfaction effects

Nutritional and Gross Metabolic: Weight loss or decreased weight gain 		FAATDF 12,333,1989
oral
dog 		lowest published toxic dose: 1,800 mg/kg/90 day- intermittent Endocrine: Changes in adrenal weight

Blood: Changes in serum composition (e.g. TP, bilirubin, cholesterol)

Blood: Changes in leukocyte (WBC) count 		BECTA6 41,704,1988
oral
guinea pig 		lowest published toxic dose: 33,750 mg/kg/60 day- intermittent Immunological Including Allergic: Decreased immune response KHZDAN 21,52,1978
oral
mouse 		lowest published toxic dose: 1,800 mg/kg/15 day- continuous Liver: Changes in liver weight

Blood: Changes in serum composition (e.g. TP, bilirubin, cholesterol)

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Peptidases 		BECTA6 42,301,1989
oral
mouse 		lowest published toxic dose: 163,800 mg/kg/104 week- continuous Liver: Tumors HBPTO* 1,814,2001
oral
rat 		lowest published toxic dose: 2,520 mg/kg/7 day- continuous Liver: Other changes AEHLAU 47,314,1992
oral
rat 		lowest published toxic dose: 3 gm/kg/15 day- continuous Liver: Changes in liver weight

Blood: Changes in serum composition (e.g. TP, bilirubin, cholesterol)

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Peptidases 		BECTA6 42,301,1989
oral
rat 		lowest published toxic dose: 42 gm/kg/30 day- continuous Brain and Coverings: Changes in brain weight

Liver: Changes in liver weight

Blood: Changes in other cell count (unspecified) 		APTOD9 19,A97,1980
oral
rat 		lowest published toxic dose: 3,420 mg/kg/76 day- intermittent Reproductive: Paternal effects: Spermatogenesis (including genetic material, sperm morphology, motility, and count)

Reproductive: Paternal effects: Testes, epididymis, sperm duct

Related to Chronic Data: Changes in testicular weight 		JTEHD6 25,285,1988


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 10 mg/m3 DTLVS* TLV/BEI,2003
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value Not Classifiable as a Human Carcinogen DTLVS* TLV/BEI,2003
TOXICOLOGY REVIEW
MUREAV 557,109,2004
TOXICOLOGY REVIEW
RREVAH 63,1,1976
TOXICOLOGY REVIEW
TOLED5 140-141,53,2003
TOXICOLOGY REVIEW
MUREAV 562,77,2004


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC 54,7740,1989
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF PESTICIDES: Supported RBREV* -,89,1998
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) 8 hour time-weighted average 15 mg/m3, total dust CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) 8 hour time-weighted average 5 mg/m3, respirable fraction CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) 8 hour time-weighted average 15 mg/m3, total dust CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) 8 hour time-weighted average 5 mg/m3, respirable fraction CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) 8 hour time-weighted average 15 mg/m3, total dust CFRGBR 29,1915.1000,1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) 8 hour time-weighted average 5 mg/m3, respirable fraction CFRGBR 29,1915.1000,1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors) 8 hour time-weighted average 15 mg/m3, total dust CFRGBR 41,50-204.50,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors) 8 hour time-weighted average 5 mg/m3, respirable fraction CFRGBR 41,50-204.50,1994
Occupational Exposure Limit - AUSTRALIA time-weighted average 0.8 ppm (10 mg/m3), JAN1993
Occupational Exposure Limit - BELGIUM time-weighted average 0.84 ppm (10 mg/m3), JAN1993
Occupational Exposure Limit - DENMARK time-weighted average 5 mg/m3, JAN1999
Occupational Exposure Limit - FINLAND time-weighted average 0.8 ppm (10 mg/m3), short term exposure limit 2.4 ppm (30 mg/m3), Skin, JAN1993
Occupational Exposure Limit - FRANCE VME 0.8 ppm (10 mg/m3), JAN1999
Occupational Exposure Limit - SWITZERLAND MAK- week 0.8 ppm (10 mg/m3), JAN1999
Occupational Exposure Limit - UNITED KINGDOM time-weighted average 10 mg/m3, short term exposure limit 15 mg/m3, SEP2000
Occupational Exposure Limit - THE NETHERLANDS MAC-TGG 10 mg/m3, 2003
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN, KOREA American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

Not Classifiable as a Human Carcinogen
Occupational Exposure Limit IN NEW ZEALAND, SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
Not Classifiable as a Human Carcinogen


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: X2223;
Number of Industries 4;
Total Number of Facilities 361;
Number of Occupations 2;
Total Number of Employees Exposed 4,189;
Total Number of Female Employees Exposed 378


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA GENETOX PROGRAM 1988, Positive: Aspergillus-aneuploidy; TRP reversion
EPA GENETOX PROGRAM 1988, Negative: Aspergillus-recombination; Host-mediated assay
EPA GENETOX PROGRAM 1988, Negative: S cerevisiae gene conversion
EPA GENETOX PROGRAM 1988, Inconclusive: TRP reversion
EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used as an agricultural chemical and pesticide, pharmaceutical and veterinary drug
EPA TSCA Section 8(d) unpublished health/safety studies
On EPA IRIS database
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE
40YJAX "Evaluation of Embryotoxicity, Mutagenicity and Carcinogenicity Risks In New Drugs, Proceedings of the Symposium on Toxicological Testing for Safety of New Drugs, 3rd, Prague, 1976," Benesova, O., et al., eds., Prague, Czechoslovakia, Univerzita Karlova, 1979
AEHLAU Archives of Environmental Health. (Heldref Pub., 4000 Albemarle St., NW, Washington, DC 20016) V.1- 1960-
ANYAA9 Annals of the New York Academy of Sciences. (New York Academy of Sciences, 2 E. 63rd St., New York, NY 10021) V.1- 1877-
APTOD9 Abstracts of Papers, Society of Toxicology. Annual Meetings. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802)
ATSUDG Archives of Toxicology, Supplement. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) No.1- 1978-
BECTA6 Bulletin of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1966-
BEXBAN Bulletin of Experimental Biology and Medicine (English Translation). Translation of BEBMAE. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) V.41- 1956-
CEYRDM Current Eye Research. (IRL Press Inc., POB 1, Enysham, Oxford OX8 1JJ, UK) V.1- 1981-
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402)
CYGEDX Cytology and Genetics (English Translation). Translation of TGANAK. (Allerton Press Inc., 150 Fifth Ave., New York, NY 10011) V.8- 1974-
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987-
EQSSDX Environmental Quality and Safety, Supplement. (Stuttgart, Fed. Rep. Ger.) V.1-5, 1975-76. Discontinued.
EVHPAZ EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.1- 1972-
FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1-40, 1981-97. For publisher information, see TOSCF2
FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982-
FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936-
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
HBPTO* Handbook of pesticide toxicology. Robert Krieger ed, Academic press, 2001
JHEMA2 Journal of Hygiene, Epidemiology, Microbiology, and Immunology. (Avicenum, Malostranske namesti 28, 11802 Prague 1, Czechoslovakia) V.1- 1957-
JNCIAM Journal of the National Cancer Institute. (Washington, DC) V.1-60, 1940-78. For publisher information, see JJIND8.
JPFCD2 Journal of Environmental Science and Health, Part B: Pesticides, Food Contaminants, and Agricultural Wastes. (Marcel Dekker, 270 Madison Ave., New York, NY 10016) V.B11- 1976-
JTEHD6 Journal of Toxicology and Environmental Health. (Hemisphere Pub., 1025 Vermont Ave., NW, Washington, DC 20005) V.1- 1975/76-
KHZDAN Khigiena i Zdraveopazvane. Hygiene and Sanitation. (Hemus, Blvd. Russki 6, Sofia, Bulgaria) V.9- 1966-
LANCAO Lancet. (7 Adam St., London WC2N 6AD, UK) V.1- 1823-
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964-
NATUAS Nature. (Nature Subscription Dept., POB 1018, Manasguan, NJ 08736) V.1- 1869-
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968-
RBREV* Status of Pesticides in Registration, Reregistration, and Special Review (Rainbow Report), Special Review and Reregistration Division Office of Pesticide Programs U.S. Environmental Protection Agency, 401 M. Street, S.W., Washington, D.C. 20460, Spring 1998
REPTED Reproductive Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1987-
RREVAH Residue Reviews. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1962-
RSTUDV Rivista di Scienza e Technologia degli Alimenti e di Nutrizione Umana. Review of Science and Technology of Food and Human Nutrition. (Bologna, Italy) V.5-6, 1975-76. Discontinued.
TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977-
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959-
TXCYAC Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973-
WRPCA2 World Review of Pest Control. (London, UK) V.1-10, 1962-71. Discontinued.

Used as an agricultural chemical and pesticide, pharmaceutical and veterinary drug

RTECS Compound Description:
   Agricultural Chemical
   Mutagen
   Reproductive Effector
   Primary Irritant

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