The Registry of Toxic Effects of Chemical Substances

Benzenesulfonic acid, 4,4' - oxybis - , dihydrazide

RTECS #: DB7321000

CAS #: 80-51-3

UPDATE: May 2004 MW: 358.42 MF: C12H14N4O5S2


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. MUTATION DATA:
  3. REVIEWS:
  4. NIOSH DOCUMENTATION AND SURVEILLANCE:
  5. STATUS IN FEDERAL AGENCIES:
  6. REFERENCES:

SYNONYMS:

  1. Benzenesulfonic acid, oxybis - , dihydrazide (9CI)
  2. Cellmic S
  3. Celogen OT
  4. Cenitron OB
  5. OBSH
  1. p,p' - Oxybisbenzene disulfonylhydrazide
  2. Oxybisbenzenesulfonic acid dihydrazide
  3. Oxybis (benzenesulfonylhydrazide)
  4. p,p' - Oxybis (benzenesulfonyl hydrazide)


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
DNA repair mouse liver 100 µmol/L JJCREP 79,204,1988
DNA repair rat liver 100 µmol/L JJCREP 79,204,1988
mutation in microorganisms Salmonella typhimurium 800 µg/plate (+enzymatic activation step) NEZAAQ 33,474,1978


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 0.1 mg/m3 ( intermittent) DTLVS* TLV/BEI,2003


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 84832;
Number of Industries 5;
Total Number of Facilities 115;
Number of Occupations 10;
Total Number of Employees Exposed 1,078
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 84832;
Number of Industries 6;
Total Number of Facilities 223;
Number of Occupations 16;
Total Number of Employees Exposed 5,939;
Total Number of Female Employees Exposed 282


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY


REFERENCES:

CODEN
REFERENCE
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
JJCREP Japanese Journal of Cancer Research. (Elsevier Science Pub. BV, POB 211, 1000 AE Amsterdam, Netherlands) V.76- 1985-
NEZAAQ Nippon Eiseigaku Zasshi. Japanese Journal of Hygiene. (Nippon Eisei Gakkai, c/o Kyoto Daigaku Igakubu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.1- 1946-

Used as cellular elastomer-resin blends for pipe insulation, sporting goods

RTECS Compound Description:
   Mutagen

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