The Registry of Toxic Effects of Chemical Substances
Benzenesulfonic acid, dodecyl - , sodium salt |
UPDATE: August 2003 | MW: 348.52 | MF: C18H29O3S•Na |
SYNONYMS: | |
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SKIN AND EYE IRRITATION DATA AND REFERENCES: | |||
ROUTE/ ORGANISM | DOSE |
EFFECT | REFERENCE |
eye rabbit | 250 µg/24 hour | severe | 85JCAE -,1063,1986 |
eye rabbit | 1% | severe | JAPMA8 38,428,1949 |
skin rabbit | 20 mg/24 hour | moderate | 85JCAE -,1063,1986 |
MUTATION DATA AND REFERENCES: | |||
SYSTEM TEST |
ROUTE/ ORGANISM/ TISSUE | DOSE | REFERENCE |
N/R | N/R | N/R | N/R |
REPRODUCTIVE EFFECTS DATA AND REFERENCES: | |||
ROUTE/ ORGANISM | DOSE |
EFFECT | REFERENCE |
N/R | N/R | N/R | N/R |
TUMORIGENIC DATA AND REFERENCES: | |||
ROUTE/ ORGANISM | DOSE |
EFFECT | REFERENCE |
N/R | N/R | N/R | N/R |
ACUTE TOXICITY DATA AND REFERENCES: | |||
ROUTE/ ORGANISM | DOSE |
EFFECT | REFERENCE |
intravenous mouse | lethal dose (50 percent kill): 105 mg/kg | N/R | JAPMA8 38,428,1949 |
oral mouse | lethal dose (50 percent kill): 1,330 mg/kg |
Peripheral Nerve and Sensation: Spastic paralysis with/without sensory change Behavioral: Convulsions or effect on seizure threshold Gastrointestinal: Hypermotility, diarrhea | TRENAF 24,397,1972 |
oral rat | lethal dose (50 percent kill): 438 mg/kg |
Eye: Lacrimation Behavioral: Somnolence (general depressed activity) Gastrointestinal: Hypermotility, diarrhea | TRENAF 24,397,1972 |
OTHER MULTIPLE DOSE DATA AND REFERENCES: | |||
ROUTE/ ORGANISM | DOSE |
EFFECT | REFERENCE |
oral mouse | lowest published toxic dose: 5 gm/kg/30 day- intermittent | Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field | JAPMA8 38,428,1949 |
oral rat | lowest published toxic dose: 3,040 mg/kg/30 day- continuous |
Liver: Other changes Blood: Changes in serum composition (e.g. TP, bilirubin, cholesterol) Nutritional and Gross Metabolic: Changes in: Fe | AECTCV 3,115,1975 |
REVIEWS: | ||
ORGANIZATION | STANDARD |
REFERENCE |
N/R | N/R | N/R |
STANDARDS AND REGULATIONS: | ||
ORGANIZATION | STANDARD |
REFERENCE |
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1988 | PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION | FEREAC 54,7740,1989 |
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF | PESTICIDES: Supported | RBREV* -,294,1998 |
NIOSH DOCUMENTATION AND SURVEILLANCE: | ||
ORGANIZATION | STANDARD or SURVEY |
REFERENCE |
National Occupational Hazard Survey 1974 |
National Occupational Hazard Survey 1974: Hazard Code: 69000; Number of Industries 207; Total Number of Facilities 52,395; Number of Occupations 127; Total Number of Employees Exposed 367,710 | |
National Occupational Exposure Survey 1983 |
National Occupational Exposure Survey 1983: Hazard Code: 69000; Number of Industries 284; Total Number of Facilities 56,584; Number of Occupations 163; Total Number of Employees Exposed 977,517; Total Number of Female Employees Exposed 423,998 |
STATUS IN FEDERAL AGENCIES: | |
ORGANIZATION |
REFERENCE |
EPA TSCA Section 8(b) CHEMICAL INVENTORY | |
Used as an anionic detergent | |
EPA TSCA Section 8(d) unpublished health/safety studies | |
EPA TSCA Section 8(e) Risk Notification, 8EHQ-0892-9017;8EHQ-0892-8846 | |
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001 |
REFERENCES: | |
CODEN |
REFERENCE |
85JCAE | "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 |
AECTCV | Archives of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 070944) V.1- 1973- |
FEREAC | Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- |
JAPMA8 | Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. |
RBREV* | Status of Pesticides in Registration, Reregistration, and Special Review (Rainbow Report), Special Review and Reregistration Division Office of Pesticide Programs U.S. Environmental Protection Agency, 401 M. Street, S.W., Washington, D.C. 20460, Spring 1998 |
TRENAF | Kenkyu Nenpo--Tokyo-toritsu Eisei Kenkyusho. Annual Report of Tokyo Metropolitan Research Laboratory of Public Health. (Tokyo-toritsu Eisei Kenkyusho, 24-1, 3-chome, Hyakunin-cho, Shin-juku-ku, Tokyo 160, Japan) V.1- 1949/50- |