The Registry of Toxic Effects of Chemical Substances
Benzenesulfonic acid, dodecyl - , sodium salt |
UPDATE: August 2003 | MW: 348.52 | MF: C18H29O3S•Na |
SYNONYMS:
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SKIN AND EYE IRRITATION DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
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eye | rabbit
250 µg/24 hour
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severe
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85JCAE -,1063,1986
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eye | rabbit
1%
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severe
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JAPMA8 38,428,1949
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skin | rabbit
20 mg/24 hour
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moderate
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85JCAE -,1063,1986
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MUTATION DATA AND REFERENCES:
SYSTEM TEST
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ROUTE/ | ORGANISM/ TISSUE
DOSE
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REFERENCE
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N/R
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N/R
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N/R
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N/R
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REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
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N/R |
N/R
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N/R
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N/R
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TUMORIGENIC DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
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N/R |
N/R
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N/R
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N/R
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ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
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intravenous | mouse
lethal dose (50 percent kill): 105 mg/kg
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N/R
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JAPMA8 38,428,1949
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oral | mouse
lethal dose (50 percent kill): 1,330 mg/kg
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Peripheral Nerve and Sensation: Spastic paralysis with/without sensory change | Behavioral: Convulsions or effect on seizure threshold Gastrointestinal: Hypermotility, diarrhea
TRENAF 24,397,1972
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oral | rat
lethal dose (50 percent kill): 438 mg/kg
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Eye: Lacrimation | Behavioral: Somnolence (general depressed activity) Gastrointestinal: Hypermotility, diarrhea
TRENAF 24,397,1972
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OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
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oral | mouse
lowest published toxic dose: 5 gm/kg/30 day- intermittent
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Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field
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JAPMA8 38,428,1949
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oral | rat
lowest published toxic dose: 3,040 mg/kg/30 day- continuous
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Liver: Other changes | Blood: Changes in serum composition (e.g. TP, bilirubin, cholesterol) Nutritional and Gross Metabolic: Changes in: Fe
AECTCV 3,115,1975
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REVIEWS:
ORGANIZATION
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STANDARD
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REFERENCE
N/R
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N/R
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N/R
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STANDARDS AND REGULATIONS:
ORGANIZATION
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STANDARD
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REFERENCE
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1988
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PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION
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FEREAC 54,7740,1989
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Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF
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PESTICIDES: Supported
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RBREV* -,294,1998
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NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION
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STANDARD or SURVEY
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REFERENCE
National Occupational Hazard Survey 1974
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National Occupational Hazard Survey 1974: Hazard Code: 69000; | Number of Industries 207; Total Number of Facilities 52,395; Number of Occupations 127; Total Number of Employees Exposed 367,710
National Occupational Exposure Survey 1983
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National Occupational Exposure Survey 1983: Hazard Code: 69000 |
![]() Number of Industries 284; Total Number of Facilities 56,584; Number of Occupations 163; Total Number of Employees Exposed 977,517; Total Number of Female Employees Exposed 423,998 |
STATUS IN FEDERAL AGENCIES:
ORGANIZATION
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REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
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Used as an anionic detergent
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EPA TSCA Section 8(d) unpublished health/safety studies
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EPA TSCA Section 8(e) Risk Notification, 8EHQ-0892-9017;8EHQ-0892-8846
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EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
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REFERENCES:
CODEN
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REFERENCE
85JCAE
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"Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia,
Avicenum, 1986
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AECTCV
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Archives of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc.,
Service Center, 44 Hartz Way, Secaucus, NJ 070944) V.1- 1973-
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FEREAC
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Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402)
V.1- 1936-
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JAPMA8
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Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC)
V.29-49, 1940-60. For publisher information, see JPMSAE.
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RBREV*
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Status of Pesticides in Registration, Reregistration, and Special Review (Rainbow Report),
Special Review and Reregistration Division Office of Pesticide Programs U.S. Environmental
Protection Agency, 401 M. Street, S.W., Washington, D.C. 20460, Spring 1998
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TRENAF
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Kenkyu Nenpo--Tokyo-toritsu Eisei Kenkyusho. Annual Report of Tokyo Metropolitan Research
Laboratory of Public Health. (Tokyo-toritsu Eisei Kenkyusho, 24-1, 3-chome, Hyakunin-cho,
Shin-juku-ku, Tokyo 160, Japan) V.1- 1949/50-
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