UPDATE: February 2004 | MW: 419.93 | MF: C25H22ClNO3 |
SYNONYMS:
|
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SKIN AND EYE IRRITATION DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
N/R |
N/R
|
N/R
|
N/R
|
|
MUTATION DATA AND REFERENCES:
SYSTEM TEST
|
ROUTE/ | ORGANISM/ TISSUE
DOSE
|
REFERENCE
|
N/R
|
N/R
|
N/R
|
N/R
|
|
REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
unreported route | mammal (species unspecified)
lowest published toxic dose: 5 mg/kg (multigenerations)
|
Reproductive: Effects on fertility: Litter size (e.g., # fetuses per litter; measured before birth) | Reproductive: Effects on newborn: Growth statistics (e.g., reduced weight gain)
FEREAC 63,48609,1998
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TUMORIGENIC DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
oral | rat
lowest published toxic dose: 45,600 mg/kg/2 year- continuous
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Tumorigenic: Carcinogenic by RTECS criteria
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FEREAC 63,48609,1998
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|
ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
oral | mammal (species unspecified)
lethal dose (50 percent kill): 87.2 mg/kg
|
N/R
|
FEREAC 63,48609,1998
|
oral | rat
lethal dose (50 percent kill): 325 mg/kg
|
N/R
|
FMCHA2 -,C287,1991
|
skin | mammal (species unspecified)
lethal dose (50 percent kill): 2,000 mg/kg
|
N/R
|
FEREAC 63,48609,1998
|
skin | rat
lethal dose (50 percent kill): >5 gm/kg
|
N/R
|
FMCHA2 -,C287,1991
|
skin | rabbit
lethal dose (50 percent kill): >2 gm/kg
|
N/R
|
FMCHA2 -,C27,1991
|
|
OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
N/R |
N/R
|
N/R
|
N/R
|
|
REVIEWS:
ORGANIZATION
|
STANDARD
|
|
REFERENCE
International Agency for Research on Cancer (IARC) Cancer Review
|
Animal Inadequate Evidence
|
IMEMDT 53,309,1991
|
International Agency for Research on Cancer (IARC) Cancer Review
|
Human No Available Data
|
IMEMDT 53,309,1991
|
International Agency for Research on Cancer (IARC) Cancer Review
|
Group 3
|
IMEMDT 53,309,1991
|
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STANDARDS AND REGULATIONS:
ORGANIZATION
|
STANDARD
|
|
REFERENCE
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF
|
PESTICIDES: Active registration
|
RBREV* -,368,1998
|
|
NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION
|
STANDARD or SURVEY
|
|
REFERENCE
N/R
|
N/R
|
N/R
|
|
STATUS IN FEDERAL AGENCIES:
ORGANIZATION
|
|
REFERENCE
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
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REFERENCES:
CODEN
|
|
REFERENCE
FEREAC
|
Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402)
V.1- 1936-
|
FMCHA2
|
Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094)
|
IMEMDT
|
IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications
Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972-
|
RBREV*
|
Status of Pesticides in Registration, Reregistration, and Special Review (Rainbow Report),
Special Review and Reregistration Division Office of Pesticide Programs U.S. Environmental
Protection Agency, 401 M. Street, S.W., Washington, D.C. 20460, Spring 1998
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