The Registry of Toxic Effects of Chemical Substances

Benzamide, N - (3 - (1 - methylethoxy) phenyl) - 2 - (trifluoromethyl) -

RTECS #: CV5581320

CAS #: 66332-96-5

UPDATE: February 2004 MW: 323.34 MF: C17H16F3NO2


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. ACUTE TOXICITY DATA:
  3. OTHER MULTIPLE DOSE DATA:
  4. STANDARDS AND REGULATIONS:
  5. STATUS IN FEDERAL AGENCIES:
  6. REFERENCES:

SYNONYMS:

  1. Flutolanil
  2. Moncut
  3. N - (3 - (1 - Methylethoxy) phenyl) - 2 - (trifluoromethyl) benzamide
  1. NNF - 136
  2. alpha,alpha,alpha - Trifluoro - 3' - isopropoxy - o - toluanelide
  3. alpha,alpha,alpha - Trifluoro - 3' - isopropoxy - o - toluanilide


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
inhalation
mammal (species unspecified) 		lethal concentration (50 percent kill): 5.98 gm/m3 N/R FEREAC 66,10817,2001
intraperitoneal
mouse 		lethal dose (50 percent kill): >10 gm/kg N/R NNGADV 13,153,1988
intraperitoneal
rat 		lethal dose (50 percent kill): >10 gm/kg N/R NNGADV 13,153,1988
oral
mammal (species unspecified) 		lethal dose (50 percent kill): 10 gm/kg N/R FEREAC 66,10817,2001
oral
mouse 		lethal dose (50 percent kill): >10 gm/kg N/R PEMNDP 9,426,1991
oral
rat 		lethal dose (50 percent kill): 10 gm/kg N/R FMCHA2 -,C209,1991
subcutaneous
mouse 		lethal dose (50 percent kill): >10 gm/kg N/R NNGADV 13,153,1988
subcutaneous
rat 		lethal dose (50 percent kill): >10 gm/kg N/R NNGADV 13,153,1988
skin
mammal (species unspecified) 		lethal dose (50 percent kill): 2 gm/kg N/R FEREAC 66,10817,2001
skin
rat 		lethal dose (50 percent kill): >5 gm/kg N/R JPIFAN (47),23,1985


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
oral
dog 		lowest published toxic dose: 913 gm/kg/2 year- intermittent Gastrointestinal: Ulceration or bleeding from duodeum

Gastrointestinal: Nausea or vomiting

Nutritional and Gross Metabolic: Weight loss or decreased weight gain 		NNGADV 13,153,1988
oral
dog 		lowest published toxic dose: 36,000 mg/kg/90 day- intermittent Liver: Other changes FEREAC 66,10817,2001
oral
dog 		lowest published toxic dose: 36 gm/kg/90 day- continuous Liver: Changes in liver weight HBPTO* 2,1197,2001
oral
dog 		lowest published toxic dose: 182.5 gm/kg/2 year- continuous Gastrointestinal: Changes in structure or function of salivary glands

Gastrointestinal: Nausea or vomiting

Nutritional and Gross Metabolic: Weight loss or decreased weight gain 		HBPTO* 2,1197,2001
oral
rat 		lowest published toxic dose: 18 gm/kg/30 day- continuous Liver: Other changes

Liver: Changes in liver weight

Blood: Changes in serum composition (e.g. TP, bilirubin, cholesterol) 		NNGADV 13,153,1988
oral
rat 		lowest published toxic dose: 438 gm/kg/2 year- continuous Liver: Other changes

Liver: Changes in liver weight

Kidney, Ureter, and Bladder: Changes in bladder weight 		NNGADV 13,153,1988
oral
rat 		lowest published toxic dose: 26,910 mg/kg/90 day- intermittent Liver: Changes in liver weight

Nutritional and Gross Metabolic: Weight loss or decreased weight gain 		FEREAC 66,10817,2001
oral
rat 		lowest published toxic dose: 26,910 mg/kg/90 day- intermittent Liver: Changes in liver weight FEREAC 66,10817,2001
oral
rat 		lowest published toxic dose: 18 gm/kg/90 day- continuous Liver: Changes in liver weight HBPTO* 2,1197,2001


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF PESTICIDES: Active registration RBREV* -,371,1998
Occupational Exposure Limit - JAPAN Occupational Exposure Limit 10 mg/m3, JAN1999


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
N/R N/R N/R


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
On EPA IRIS database


REFERENCES:

CODEN
REFERENCE
FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936-
FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094)
HBPTO* Handbook of pesticide toxicology. Robert Krieger ed, Academic press, 2001
JPIFAN Japan Pesticide Information. (Japan Plant Protection Assoc., 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) No.1-61, 1969-92. For publisher information, see AGJAEP.
NNGADV Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. (Nippon Noyaku Gakkai, 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) V.1- 1976-
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968-
RBREV* Status of Pesticides in Registration, Reregistration, and Special Review (Rainbow Report), Special Review and Reregistration Division Office of Pesticide Programs U.S. Environmental Protection Agency, 401 M. Street, S.W., Washington, D.C. 20460, Spring 1998

Used as systemic fungicide

RTECS Compound Description:
   Agricultural Chemical

ALT CAS #: 84461-35-8
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